Long-term consumption of sugar substitutes will interfere with amino acid metabolism and affect the balance of neurotransmitters, such as affecting the level of catecholamines in the brain, making the nervous system excessively excited, which is not conducive to the anti-anxiety and anti-depression function of the human body.

In terms of mechanism, sweeteners make people feel sweet, but they can't cause the corresponding increase of blood sugar, which belongs to "cheating" on the human metabolic system. This long-term and repeated cheating is easy to cause the disorder of metabolic regulation mechanism.

Extended data:

Long-term consumption of calorie-free sugar substitutes will not lose weight, but will easily increase weight and increase the prevalence of diabetes. However, the study pointed out that if only short-term consumption of sugar substitutes will not lead to excessive weight gain, only long-term consumption will have side effects.

According to the research in the journal of Nutrition and Diabetes Association, 25% of children and 40% of adults use artificial sweetener sugar to replace sugar, and it is expected that the amount of sugar substitute will continue to increase. In the study published in the journal of Canadian Medical Association, researchers tracked and compared more than 400,000 people in 10 to 30 years. The results showed that these people all had the trend of weight gain and diabetes.

People's Daily Online-Can young people really have their cake and eat it?

People's Daily Online-Research shows that eating sugar substitutes for a long time not only does not lose weight, but is easy to gain weight and get sick.