The artificial bezoar metronidazole capsule with metronidazole and artificial bezoar as the main components has the following pharmacological effects: metronidazole has a strong antibacterial effect on most anaerobic bacteria. Antibacterial spectrum includes Bacteroides fragilis and other Bacteroides, Bordetella, Bordetella aerogenes, Eubacterium, Veillococcus, Digestive coccus, and Digestive Streptococcus. Its bactericidal concentration is slightly higher than its bacteriostatic concentration. The bactericidal mechanism of metronidazole has not been fully clarified. Nitro reductase of anaerobic bacteria plays an important role in energy metabolism of sensitive strains. The nitro group of this product is reduced to a cytotoxicity, which acts on the DNA metabolism process of cells and promotes the death of bacteria. Drug-resistant bacteria often lack nitroreductase and are resistant to metronidazole. Artificial bezoar has antipyretic and anti-inflammatory effects.

Therefore, artificial bezoar metronidazole capsule can be used to treat acute pericoronitis of wisdom teeth, local alveolar abscess, pulpitis, periapical periodontitis and other diseases by using antibacterial, bactericidal, antipyretic and anti-inflammatory effects. However, the side effects of artificial bezoar metronidazole capsules are still obvious.

For example, artificial bezoar metronidazole capsules have harmful effects on the stomach, which will cause gastrointestinal reactions in patients taking the medicine, such as nausea, loss of appetite, vomiting, diarrhea, abdominal discomfort, taste changes, dry mouth and metallic taste in the mouth. In addition, allergic reactions such as rash, urticaria and itching may occur, as well as central nervous system symptoms such as headache, dizziness, syncope, paresthesia, numbness of limbs, ataxia and insanity. These adverse reactions are reversible and will recover by themselves after stopping the drug.

However, the most serious adverse reaction of taking artificial Niuhuang metronidazole capsule is that it can cause seizures and peripheral neuropathy at high dose, and the latter is mainly manifested as numbness and paresthesia of extremities. In some cases, persistent peripheral neuropathy can occur when taking drugs for a long time. It is suggested that once the patient is out of danger, he should stop taking the medicine immediately and seek medical treatment in time.

Patients who are allergic to metronidazole or pyrrole drugs, pregnant women and drinkers should not take artificial bezoar metronidazole capsules. Ask other patients to consult a professional doctor if they want to take them.