Specifications: 5mg*15 tablets
Manufacturer: Chongqing Huabang Pharmaceutical Co.
Approval information: H20040249
Qualification: Qualified
This product is a prescription drug, and the State Pharmaceutical Administration stipulates that prescription drugs are not allowed to be sold on the Internet, so if you already have a prescription from your doctor, you can go to BAYAN with the prescription. If you have a prescription from a doctor, you can buy it from a physical pharmacy of Baiyang Health Pharmacy with this prescription.
Baiyang health pharmacy online legal online pharmacy all products authenticity guarantee, and provide you with the most comprehensive levocetirizine hydrochloride tablets instructions. The price of Levocetirizine Hydrochloride Tablets from BAYANG online pharmacy is $23.90, and the effects of Levocetirizine Hydrochloride Tablets are as follows:
Generic Name: Levocetirizine Hydrochloride Tablets
Ingredients:
Levocetirizine Hydrochloride Tablets. Chemical name:R-(-)2-[2-[4-[4-(chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]acetic acid dihydrochloride.
CharacteristicsThis product is white or off-white tablets.
Pharmacology:This product is an oral selective histamine H1 receptor antagonist. There is no obvious anticholinergic and anti-5-hydroxytryptamine effect, the central inhibition effect is small. Toxicological studies: Genotoxicity: Ames test, human lymphocyte aberration test, mouse lymphoma test and rat micronucleus test were all negative. Reproductive toxicity: The results of fertility and general reproductive toxicity tests in mice indicate that cetirizine does not impair fertility when administered orally at doses up to 64 mg/kg (approximately 25 times the maximum recommended daily oral dose for adults, based on body surface area). No teratogenic effects were observed in mice, rats and rabbits when administered orally at doses up to 96, 225 and 135 mg/kg (approximately 40, 180 and 220 times the maximum recommended daily oral clinical dose for adults, respectively, based on body surface area). However, there is no information available on adequate and tightly controlled clinical studies in pregnant women. Since animal reproduction studies are not always predictive of human effects, the drug should be administered during pregnancy only when indicated. Oral administration to lactating mice (females) at doses up to 96 mg/Kg (approximately 40th percentile of the clinically recommended maximum daily oral dose for adults, converted to body surface area) resulted in delayed growth of pups.Studies in Beagler dogs have shown that approximately 3% of the administered dose is excreted in milk. Carcinogenicity:In a carcinogenicity test in rats administered orally for 2 consecutive years, no carcinogenicity was observed at doses up to 20 mg/Kg (approximately 15 times the clinically recommended maximum daily oral dose for adults or 10 times the clinically recommended maximum daily dose for children when converted to body surface area). In the carcinogenicity test in mice administered orally for 2 consecutive years, a dose of 16 mg/Kg (equivalent to approximately 6 times the clinically recommended maximum daily oral dose for adults or 4 times the clinically recommended maximum daily dose for children when converted to body surface area) induced an increase in the incidence of benign tumors in males; a dose of 4 mg/Kg (equivalent to approximately 2 times the clinically recommended maximum daily oral dose for adults or 4 times the clinically recommended maximum daily dose for children when converted to body surface area) induced an increase in the incidence of benign tumors in males, while a dose of 4 mg/Kg (equivalent to approximately 2 times the clinically recommended maximum daily oral dose for adults or 2 times the clinically recommended maximum daily dose for children when converted to body surface area) caused no carcinogenicity. At a dose of 4 mg/Kg (approximately 2 times the maximum recommended daily oral dose for adults or the maximum recommended daily dose for children), no increase in the incidence of liver tumors was observed. The clinical significance of these findings is not clear.
PharmacokineticsOral absorption is rapid, with a peak time of tmax=0.7-1 hour and a bioavailability of >96%. Coadministration of the drug with food slightly prolongs the time of onset of action and reduces the peak concentration (approximately 20%). The protein binding rate of this product is 96%, the average performance of the volume of distribution 26.9L, the concentration in the brain is less than 1/10 of the plasma concentration, this product does not go through the hepatic metabolism, elimination half-life of 7-8 hours, the vast majority of the drug in the form of prophylactic form of excretion through the kidneys, the urinary excretion accounted for 85%, fecal excretion accounted for 13%.
Indications:
It is used to relieve allergic symptoms of allergic diseases, such as allergic rhinitis (including eye allergy), urticaria, angioneurotic edema, contact dermatitis, insect bite dermatitis and other allergic diseases of the skin and mucous membranes; used to alleviate allergic symptoms of colds.
Use and dosage orally, adults and children over 6 years of age, the dosage is once a day, each time a prescription. 2-6 years of age, once a day, each time half a tablet.
Adverse effectsThis product is well tolerated, adverse effects are mild and can be self-cured, common adverse effects include drowsiness, dry mouth, headache, fatigue and so on.
ContraindicationsAllergy to this product and other excipients is prohibited.
Precautions 1. Use with caution if you have a history of liver dysfunction or disorders.
2. Use with caution during work at height, driving or operating machinery.
3. Avoid taking with sedatives.
4. Avoid using this product after drinking.
5. Reduce the dosage of this product in patients with impaired renal function.
Pregnant women and lactating women should not use this product during pregnancy and lactation.
Children The safety of this drug in children under 2 years of age has not been established.
Elderly patients Usually the physiological functions of the elderly decline, need to be careful with the use of this product.
Drug Interactions No drug interaction studies have been conducted with this product. There are no interactions between cetirizine and pseudoephedrine, cimetidine, ketoconazole, erythromycin, azithromycin, glipizide and Valium.
Overdose There is no specific antagonist for this product, and gastric lavage should be performed immediately for severe overdose.
Storage: Sealed and kept in a dry place.
Temporary expiration date of 24 months
The above is the instruction of Levocetirizine Hydrochloride Tablets, we hope that you can know more about this product. The price of Levocetirizine Hydrochloride Tablets is $23.90, which is reasonable.