Freckles are a kind of autosomal dominant hereditary pigmentation spots, which are derived from the genetic inheritance from the previous generation. Everyone in the freckle family has this freckle fragment in their genes, which is passed down from generation to generation, but not everyone shows it. Freckles, like the five human fingers, the color of the skin, the size of the eyes, and many other human genetic features, are a characteristic manifestation of genetic influences from previous generations.

These human genetic features are subjected to artificial modification, which can change their manifestation characteristics, such as surgical removal of diseased tissues, Jacobson's bleaching of the skin for the sake of beauty, contemporary artificial beauty with double eyelids and so on, and the same reasoning for removing freckles for the sake of beauty. When this artificial modification (medical practice) is successful in a particular person, it does not mean that the person's genes have changed, and his or her offspring will continue to exhibit the genetic traits of their predecessors as usual, because their genes have not changed.

"Incurable" means, precisely, that current science has not been able to solve the problem of the transmission of freckle genes from one generation to the next, not the restoration of artificially modified traits to their original state (recurrence). Can a traumatized missing finger grow back? Can an inflamed appendix grow back after removal? The answer is no. However, their offspring will still exhibit the genetic characteristics of the five-fingered appendix intact. The same is true for freckles.

Getting rid of freckles for people who exhibit them has long been a fait accompli. But it is not yet possible to block the transmission of freckles from generation to generation at the genetic level.

China's scientists have recently locked the human freckle-causing gene in the region of 32-34 bands on the long arm of chromosome 4. This means that in the future, freckles can be completely eliminated from the genetic level. The "eradication" of freckles is just around the corner. But there is still a long way to go before freckles can be eliminated genetically.

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