pharmacological action
1, anti-tumor effect: anti-tumor effect, cicada flower anti-tumor, preventing the spread and metastasis of cancer cells is achieved by improving the immunity of patients. Director Derek lv of China Cancer Prevention Network and authoritative cancer experts at home and abroad believe that the fundamental cause of cancer is the decline of patients' immunity. The immune system is the natural barrier of human body, which can produce immune protection such as anti-cancer and maintain the physiological balance and stability of the body. For patients receiving radiotherapy and chemotherapy, it can improve the tolerance to the toxicity of radiotherapy and chemotherapy, eliminate the special pain of cancer, alleviate or eliminate the side effects such as leukopenia, alopecia, anorexia and vomiting caused by radiotherapy and chemotherapy, improve cachexia, improve the quality of life and prolong life. Galactomannan also has anti-tumor effect. 2. Regulation of central nervous system: intraperitoneal injection of natural cicada flower or artificially cultured diluted alcohol extract can obviously reduce spontaneous activity of mice, prolong the sleep time caused by pentobarbital sodium and chloral hydrate, and improve the sleep rate of mice with subthreshold hypnotic dose of pentobarbital sodium; Prolonging the latent period of convulsion induced by central excitatory drugs strychnine and pentylenetetrazol in mice It is proved by chemical stimulation and hot plate method that both of them have obvious analgesic effect. It has obvious cooling effect on normal and yeast-induced intraperitoneal injection in rats. Other data further prove that cicada flower and its artificial culture have obvious analgesic, sedative and antipyretic effects. 3. Toxic and side effects: Acute toxicity test showed that 1 died in 20 mice after 72 hours of intragastric administration of 60g/kg ethanol extract of cicada flower. After administration, the activity of animals only decreased, and all animals returned to normal after 24 hours. The ld50 of intraperitoneal injection was12.5 2.1g/kg, and the toxic reactions were writhing, decreased activity, dyspnea and even death. Subacute toxicity test showed that three groups of rats were given 1g/kg, 3g/kg and 9g/kg respectively for 28 days. Results There were no abnormal changes in blood routine, liver, renal function and electrocardiogram, and there were no obvious abnormal changes in pathological examination of important organs such as heart, liver, spleen, lung and kidney.