I don't know if my buddies have noticed that as our standard of living improves day by day, a lot of our friends and relatives are told to have "higher uric acid" during the medical checkups and the "high uric acid" is also becoming more and more popular among the people.
According to the "The Killer of Silent Health", the "Killer of Silent Health" has become a major killer.
According to the White Paper on Gout Status Report, the number of patients with high uric acid in China has exceeded 170 million, and the prevalence rate is 10 times more than 20 years ago. It is clear that the disease of high uric acid can no longer be ignored.
What is uric acid? And how to treat and prevent it? Dr. Wheat will bring you together today to find out.
First, what is uric acid?
Uric acid is a metabolite of purine, purine is divided into endogenous and exogenous purine, exogenous mainly through the food intake, endogenous refers to the body's metabolites, purine is ultimately metabolized into uric acid, through the kidneys for excretion.
If the body produces too much to excrete or the uric acid excretion mechanism is degraded, then the body is too much uric acid accumulation, resulting in the body fluids become acidic, affecting the normal function of human cells.
2. What are the symptoms of high uric acid?
1. Gout
The most obvious symptom of high uric acid should be gout, which is due to when uric acid is high, urate is easy to crystallize and precipitate in the body of the various joints, which triggered the occurrence of gout, serious destruction of the joints, resulting in joint deformity.
2. Soreness in the waist
When the uric acid value in our body is high, it is very harmful to the kidneys, and in the long run, it will aggravate the burden on the kidneys and reduce the renal function, which in turn affects the waist.
The main reason is that the kidneys are in the waist, and the waist is the gatehouse of the kidneys, once the kidneys are out of order the waist will become weak because of a long time without the nourishment of the kidneys, and there will be soreness in the waist.
3. Blood glucose
When blood glucose is abnormally high, it is necessary to go to the hospital in a timely manner, to be vigilant is due to high uric acid.
Three, why is uric acid high?
1. Heredity
60% of high uric acid or genetically related, mainly due to an inborn defect in enzyme metabolism caused by a genetic disease.
2. Weakened kidney function
Weakened kidney function can lead to increased uric acid secretion from the glomeruli.
And for people with impaired kidney function, it will make the urinary function much weaker.
80% of the uric acid in the body is excreted by urine, and a decrease in urination means a decrease in the amount of uric acid excreted.
3. Purine metabolism is abnormal
Purine is a necessary substance for the synthesis of RNA and DNA in the body, nucleic acid will be metabolically decomposed into part of the purine, and then a series of metabolic decomposition ultimately produce uric acid.
The level of uric acid in the body depends on its own production and excretion of uric acid, the synthesis of uric acid is more, but the excretion of less will form hyperuricemia, which will accumulate into the limbs, metatarsal end, knuckles, and so on the formation of the daily common gout.
4. Excessive drinking
Excessive drinking can lead to elevated uric acid, mainly because the main component of alcohol is ethanol, ethanol can inhibit the excretion of uric acid, excessive alcohol consumption will break the balance of this inhibition.
5. Improper diet
As the saying goes, "Illness comes in through the mouth". Improper diet can also lead to elevated uric acid, mainly due to the usual regular large fish and meat, eat all kinds of high purine food, which is also the biggest trigger of high uric acid.
Four, how to prevent high uric acid?
1. Drink less
Alcohol intake will make the body of uric acid accumulation, thus inhibiting the uric acid discharge, but also increase the probability of gout, so drink less or do not drink.
2. Reduce the intake of purine substances
Purine substances are a very "unreliable" substance that affects the level of uric acid in the body, and the dietary process should be paid extra attention to;
Limit the intake of high-calorie, high-protein, and high-fat foods in your diet.
3. Drink more water
High uric acid in the body can be helped by drinking more water, because drinking water can promote the metabolism of uric acid, and flush the kidneys, relieve the pressure on the kidneys, so as not to let too much uric acid in the kidneys to accumulate.
It is recommended that people with high uric acid drink 2000ml of water a day and urinate more.
4. Do not stay up late
People with high uric acid must not stay up late. Staying up late and going to bed late can lead to endocrine disorders, and the metabolism of purine substances in the body will be disturbed, resulting in the body of uric acid can not be discharged in a timely manner.
5. Control your weight
Research has shown that excessive obesity inhibits insulin secretion, restricts purine discharge, and is not conducive to uric acid metabolism.
If you have high uric acid, you must control your weight, and obese people are prone to excess uric acid.
However, when gout, arthritis, renal colic, etc., it is already too late.
6. Adhere to exercise
Uric acid is high must not be too lazy, pay attention to the legs. Usually you can reasonably adjust your lifestyle, more aerobic exercise, such as riding, jogging, fast walking, playing ball and so on.
Once the uric acid is high, it is necessary to pay attention to regular examination. Most of the high uric acid early no obvious discomfort, easy to be ignored.
But when there are obvious symptoms, such as gout, arthritis, renal colic and so on, it is already too late.
Normal value of blood uric acid:Normal male is 150~380μmol/L (2.5~6.4mg/dl), female is 100~300μmo/l (1.6~5.0mg/dl),
2017 Kidney Disease Guidelines for men's blood uric acid maximum upper limit value 420 μmol/l and 360 μmol/l for women, above which hyperuricemia is diagnosed.
Once you find high uric acid, you must adjust your lifestyle and habits in time, and consult a doctor if necessary, so that you can find and treat it in time.
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