There are two sources of uric acid in human body, one is endogenous and the other is exogenous.
80% uric acid is endogenous, which is the product of nucleic acid metabolism in the body, and 20% is exogenous, which comes from the food we eat.
13 uric acid is excreted through the intestine and 2/3 through the kidney, and the amount of uric acid produced is equivalent to the amount excreted, so that the body is in a balanced state.
How high is uric acid?
Due to different constitutions, the uric acid values in men and women are slightly different.
The normal value of serum uric acid in adult males is 149~4 16μmol/L;
The normal value of serum uric acid in adult women is 89 ~ 357 μ mol/L;
Men over 60 years old: 250~476μmol/L;
Women over 60 years old are:190 ~ 434 μ mol/L.
In general, if the uric acid content in blood exceeds 420μmol/L, it is defined as hyperuricemia, which is the "fourth highest".
The data shows that there are about10.2 billion people with high uric acid in China at present, and it is still growing.
The harm of high uric acid
Once the urine acid is high, it will cause systemic diseases.
The first thing to bear the brunt is joint diseases. When uric acid crystal salt accumulates in joints, it will lead to arthritis, swelling, tophus and so on.
Secondly, there are different degrees of damage to blood vessels, and uric acid exceeding the standard for a long time will increase the risk of angina pectoris, myocardial infarction and stroke.
Thirdly, there is serious damage to the kidneys. Long-term high uric acid can easily lead to kidney calculi's disease, renal colic, hematuria, gouty nephropathy and even uremia, which is harmful to life and health.
Finally, it will affect blood sugar, induce diabetes, or aggravate diabetes. A study in the United States found that the risk of new diabetes increased by 18% for every 60 μmol/ L increase in blood uric acid level.
People with high uric acid will have four kinds of abnormalities, so don't ignore them.
1: joint pain and swelling
When uric acid accumulates to a certain extent, firstly, it is easy to deposit in joints, cartilage and other positions, which are mostly manifested as joint pain, swelling and acute onset.
Most of the time in the night, the joints are suddenly painful and awakened by pain, and the condition is repeated. It may also be accompanied by symptoms such as headache, brain fever, fatigue, anorexia and so on.
2. Abnormal urination at night
The frequency of getting up at night increases, and the night of urination is deep and even turbid, so be wary of uric acid exceeding the standard.
Uric acid is excreted mainly through urine. Once uric acid is excessive, it will damage kidney function and affect urination.
If this happens frequently, you should be careful that uric acid exceeds the standard, which has damaged kidney health.
3. Frequent low back pain
When you sleep at night, you often feel backache and lumbago, but you should also be alert to high uric acid and damage the kidneys.
When the human body sleeps, uric acid is easy to form urate crystals and accumulate in the kidney, which will easily lead to kidney calculi and renal colic, which will endanger the health of the kidney.
Kang, which in turn leads to pain in the waist.
If uric acid exceeds the standard seriously, at this time, it is easy to cause insomnia, so pay special attention.
4. Body edema
Uric acid crystals are the easiest to precipitate when sleeping at night.
If uric acid crystal salt blocks the glomerulus, even necrosis occurs, then the water in the body cannot be filtered and excreted normally, which leads to body edema.
If you want to reduce uric acid, stick to 8 things and reduce complications.
1, drink plenty of water
High uric acid, pay attention to drink more water, boiled water, is the best choice.
Drink at least 2000 ml of water every day to increase urine output and discharge as much uric acid as possible.
If you sweat a lot, you should increase the amount of drinking water appropriately, pay attention to drinking slowly with a small mouth and take the initiative to drink water.
2, often drink tea
Using diuretic plants and soaking in water instead of tea can better promote uric acid excretion.
Jinlanju is a kind of "medicinal and edible" food introduced from Europe, and then recorded in Pharmacopoeia.
Wash its leaves, dry them into cymbidium leaf tea, and soak them in water to reduce uric acid and gout attacks.
Chinese medicine believes that Cymbidium album has the effects of clearing away liver-fire, benefiting gallbladder, inducing diuresis and reducing swelling, and has high medicinal value.
Modern pharmacological research shows that the effective components of Cymbidium longiflorum can inhibit the action of enzymes in the process of uric acid synthesis, reduce the synthesis of uric acid, and can significantly reduce it. Hypertriglyceridemia combined with hyperuricemia can reduce uric acid and hypertriglyceridemia, and the effect is lasting and stable.
In addition, it can also improve hyperuricemia and abdominal obesity caused by high purine diet, and comprehensively adjust the interaction disorder of fat, sugar and uric acid to reduce the number of gout attacks.
3. Keep your mouth shut
Eat less foods with high purine and fructose, and limit the intake of high purine foods from the source.
Like animal viscera, roe, seafood, thick broth, beer, etc., eat less ultra-high purine foods.
High-purine foods such as livestock meat (pigs, cows, sheep, etc.), poultry meat (chickens, ducks, geese, etc.) and fish can be eaten appropriately.
However, in the period of acute attack, we should also avoid eating properly.
4. Don't drink
Alcohol is the "catalyst" of uric acid, which will inhibit uric acid metabolism and aggravate the condition.
Whether it's beer, white wine, red wine, etc., as long as it contains alcohol, you should stay away.
5. Do exercise
Choose aerobic exercise and stay away from anaerobic exercise.
The purpose of exercise is to keep fit and lose weight, and choose aerobic exercise that can consume fat.
Jogging, Tai Ji Chuan, radio exercises, brisk walking, table tennis and other items are more suitable for people with high uric acid.
Exercise for more than 30 minutes every day. If you don't exercise regularly, you can do it step by step, that is, exercise 4 to 5 times a week for 20 minutes each time, and then gradually increase the exercise time.
6. Lose weight
Studies have shown that obesity is a factor leading to many chronic diseases. Obesity can inhibit insulin secretion and limit purine excretion, which is not conducive to uric acid metabolism.
Therefore, controlling weight and not being too fat is very important for lowering uric acid and preventing gout!
7. Don't hold your urine
Holding urine can lead to uric acid retention, damage the kidney and induce renal lesions.
Kidney damage will further affect the excretion of uric acid, such a vicious circle.
Therefore, drinking more water and not holding your urine is the healthiest way.
8. Don't stay up late
People with high uric acid and gout must pay attention to controlling their sleep and don't stay up late.
Once staying up late, it will easily lead to endocrine disorders in the body, which will lead to the disorder of purine metabolism in the body, and eventually lead to the inability to excrete uric acid in the body in time, which will have a certain impact on uric acid.
In addition, lack of sleep will also lead to impaired renal function, which is not conducive to the excretion of uric acid.