1, the scientific name of PQQ is pyrroloquinoline quinone, which is a vitamin substance with high content in Japanese natto, traditional ganoderma lucidum and breast milk. It is a known cell mitochondrial energy optimizer, which helps to create new mitochondria and is the energy source of cells. PQQ is also widely found in fruits, vegetables, cereals, beverages and other common foods, including plant-derived foods and animal-derived foods, which can play a very important role in human growth and development. Moreover, PQQ has a strong ability to remove peroxide, which is embodied in: protecting mitochondria from oxidative damage.

Spermidine is a kind of natural polyamine, which is widely distributed in organisms and is biosynthesized by putrescine and adenosylmethionine. Spermidine can inhibit NO synthase (nNOS), bind and precipitate DNA. It can also be used to purify DNA binding proteins and stimulate T4 polynucleotide kinase activity. The food sources of spermidine are generally aged cheese, mushrooms, natto, green pepper, wheat germ, cauliflower, broccoli and so on. The content of spermidine in Grifola frondosa and Pleurotus ostreatus is also high.