The normal value of male uric acid is150-420 μ mo1/L.
Normal value of female uric acid: 90-360μmo 1/L (the uric acid value of female menopause gradually rises, approaching that of adult male).
Normal value of uric acid in children:180-300μ m o1/l.
When uric acid is higher than normal, it can be diagnosed as hyperuricemia. When it is hyperuricemia, it may cause gout. When it continues to rise, other diseases may occur, such as renal tuberculosis, nephritis, uremia and so on. Therefore, if uric acid is higher than normal, you should seek medical advice in time.
2 What are the hazards of gout caused by high uric acid? If blood uric acid is too high, urate will be formed. Over time, urate will deposit around limbs and joints in the form of crystals with blood flow, and compress peripheral nerves, causing numbness and pain.
The urate of tophus is deposited in connective tissue, which can gradually form tophus with different sizes. Mainly occurs in the ears and joints of hands and feet.
Hyperuricemia can directly damage pancreatic β cells and induce diabetes. There are insulin antibodies in some patients with hyperuricemia, which will aggravate the condition.
Hypertension Among untreated hypertensive patients, 22%-38% suffer from hyperuricemia, both of which can cause arteriosclerosis and nephrosclerosis, resulting in decreased renal blood flow and decreased renal uric acid excretion capacity.
Hyperuricemia induced by cerebral infarction is a risk factor for arteriosclerosis, which may affect arterioles and make cerebral infarction prone.
The incidence of hyperuricemia in patients with coronary heart disease aggravated arteriosclerosis increased significantly, and the level of serum uric acid can be used as a risk marker of cardiovascular disease death.
3 What are the factors that affect the change of uric acid? The daily production and excretion of uric acid are in a dynamic balance. When uric acid changes, the reasons can be summarized as follows.
Until puberty, the serum uric acid level was lower than that of adults, and it began to rise after puberty. However, due to the decline of renal function, the blood uric acid value of the elderly is also increasing day by day.
Usually, the uric acid value of male adults is higher than that of female adults. When women enter menopause, they have a very close relationship with men. Because of the high level of estrogen in women, estrogen can promote uric acid excretion.
The uric acid value will increase with the increase of calorie intake in calorie diet. Excessive intake of protein, fat and sugar will lead to an increase in uric acid value, which means that obese people are more likely to get hyperuricemia.
If you eat too much food containing purine, uric acid will rise.
Drinking alcohol can promote the synthesis of uric acid in the body, inhibit the excretion of uric acid and increase the uric acid value in the blood. Among alcoholic beverages, beer contains the most purine.
Intense muscle exercise can promote muscle metabolism, destroy cells, release a lot of nucleic acid and increase uric acid value.
Drugs Taking some drugs will increase uric acid level. Such as thiazide antihypertensive diuretics for the treatment of hypertension and nephropathy.
4 prevention and treatment principles of high uric acid Reasonable control of diet should control calories, low purine, low protein, low fat and low sugar diet, and ban alcohol.
Adequate drinking water requires drinking a lot of water every day, about 2000 ml per day. Uric acid is excreted through the kidneys, and enough water can excrete uric acid through urine.
A regular life system keeps a regular life schedule and avoids fatigue and staying up late. Excessive mental stress can also lead to an increase in uric acid.
Proper physical activity, proper simple physical activity can effectively regulate one's state and avoid excessive strenuous exercise, which will lead to the increase of uric acid.
Effective drugs for the treatment of uric acid increase should seek medical advice, take uric acid-lowering drugs according to the doctor's advice and control uric acid.
Regular health check to prevent uric acid is too high, you should go to the hospital for blood uric acid test regularly, so that you can know the degree of uric acid control and find uric acid is too high early.