National Standard No. 32127
CAS No. 141-78-6
Chinese name ethyl acetate
English name ethyl acetate; acetic ester
Alias ethyl acetate
Molecular formula C4H8O2; CH3COOCH2CH3 Appearance and properties Colorless clarified liquid, aromatic odor, volatile
Molecular weight 88.10 Vapor pressure 13.33kPa/27℃ Flash point:-4℃
Melting point -83.6℃ Boiling point:77.2℃ Solubility Slightly soluble in water, soluble in alcohols, ketones, ethers, chloroform and other most of the organic solvents
Density Relative density Relative density (water=1)0.90; Relative density (air=1)3.04 Stability Stable
Hazardous labeling 7 (flammable liquids) Main uses Wide range of uses, mainly used as a solvent, and used in the synthesis of dyes and some pharmaceutical intermediates
2.Impact on the environment:
I. Health hazards
Invasive pathways: inhalation, ingestion, percutaneous absorption. .
Health Hazards:
It is irritating to eyes, nose and throat. High concentration of inhalation can cause progressive anesthesia, acute pulmonary edema, liver and kidney damage. Continuous inhalation of large quantities can cause respiratory paralysis. Misuse can produce nausea, vomiting, abdominal pain, abdominal pain, diarrhea and so on. There is a sensitizing effect, bleeding gums due to vascular nerve disorder; can cause eczema-like dermatitis.
Chronic effects: long-term exposure to the product can sometimes lead to corneal clouding, secondary anemia, leukocytosis and so on.
II. Toxicological information and environmental behavior
Toxicity: low toxicity category.
Acute toxicity: LD505620mg/kg (rat oral); 4940mg/kg (rabbit oral); LC505760mg/m3, 8 hours (rat inhalation); human inhalation of 2000ppm × 60 minutes, severe toxic reaction; human inhalation of 800ppm, with disease; human inhalation of 400ppm for a short period of time, the eyes, nose, throat irritation.
Subacute and chronic toxicity: guinea pig inhalation 2000ppm, or 7.2g/m3, 65 funded exposure, no significant effects; rabbit inhalation 16000mg/m3 × 1hour/day × 40 days, anemia, leukocyte increase, organ edema and lipoatrophy.
Mutagenicity: sex chromosome deletion and non-segregation: Brewer's yeast 24400ppm. cytogenetic analysis: hamster fibroblasts 9g/L.
Hazardous properties: flammable, its vapor and air can form explosive mixtures. When exposed to open flame and high heat, it can cause combustion and explosion. Contact with oxidizer will react violently. In the fire, the heated container has the danger of explosion. The vapor is heavier than air, can be diffused to a considerable distance at a lower place, when the open fire will lead back to combustion.
Combustion (decomposition) products: carbon monoxide, carbon dioxide.
3. On-site emergency monitoring methods:
Gas Detection Tube Method
Gas Rapid Detection Tube (product of Beijing Labor Protection Institute, product of German Dr?ger)
4. Laboratory Monitoring Methods:
Gas Chromatography Method for Pump-less Sampling (WS/T155-1999, Air in the Workplace)
Gas Chromatography Method for the Determination of Harmful Substances in the Air. Determination of Hazardous Substances in Air (Second Edition), edited by Hang Shiping
Hydroxylamine-Ferric Chloride Colorimetric Method Determination of Hazardous Substances in Air (Second Edition), edited by Hang Shiping
5. Environmental Standards:
China (TJ36-79) Maximum Permissible Concentration of Hazardous Substances in Workplace Air 300mg/m3
Former USSR (1977) Atmospheric Quality Standard 0.5 mg/m3
The former Soviet Union ( 1977) Atmospheric Quality Standard 0.1mg/m3
The former Soviet Union (1975) Maximum Allowable Concentration of Hazardous Substances in Water 0.1mg/L
The former Soviet Union (1975) Sewage Discharge Standard 10mg/L
Olfactory Threshold Concentration 270mg/m3
6. Emergency Treatment and Disposal Methods:
I, Emergency treatment of leakage
Rapidly evacuate people in the leakage contaminated area to the safe area and isolate them, strictly limit the access. Cut off the source of ignition. It is recommended that emergency personnel wear self-contained positive-pressure respirators and fire protective clothing. Cut off the source of leakage as far as possible and prevent access to restricted spaces such as sewers and flood drains. SMALL SPILL: Absorb with activated carbon or other inert material. It can also be flushed with a large amount of water, and the wash water diluted and put into the wastewater system. Large quantity leakage: construct a dike or dig a pit to shelter; cover with foam to reduce vapor hazard. Use explosion-proof pumps to transfer to tanker trucks or special collectors, recycling or transported to the waste treatment site for disposal.
Two, protective measures
Respiratory protection: may be exposed to its vapors, you should wear a self-absorbing filtering gas mask (half mask). In case of emergency rescue or evacuation, it is recommended to wear an air respirator.
Eye protection: Wear chemical safety glasses.
Body protection: wear anti-static work clothes.
Hand protection: Wear rubber gloves.
Others: Smoking is strictly prohibited at the work site. After work, shower and change clothes. Attention to personal hygiene.
Three, first aid measures
Skin contact: remove contaminated clothing, use soapy water and water to rinse the skin thoroughly. Seek medical attention.
Eye contact: Lift eyelids and flush with running water or saline. Seek medical attention.
Inhalation: Remove from scene quickly to fresh air. Keep airway open. If breathing is difficult, give oxygen. If breathing stops, immediately perform artificial respiration. Seek medical attention.
Eating: drink enough warm water, induce vomiting, seek medical attention.
Fire extinguishing methods: fire extinguishing agent: anti-soluble foam, carbon dioxide, dry powder, sand. Ineffective to extinguish fire with water, but water can be used to keep the container in the fire cool.