Vitamin B6 and vitamin B12 are common water-soluble vitamins and are indispensable substances for the human body to convert sugar, fat, protein and other substances into calories. Insufficient intake of vitamin B6 and vitamin B12 for a long time can lead to vitamin B6 and vitamin B12 deficiency. We know that when the human body is deficient in nutrients, there are often some warning signs or symptoms. So, what are the symptoms if the human body is deficient in vitamin B6 and vitamin B12?

What are the symptoms of vitamin B6 and vitamin B12 deficiency in the body?

Vitamin B6 has two derivatives, namely pyridoxal and pyridoxamine, which are substances with the same effect and can be converted into each other in the human body. Vitamin B6 is converted into pyridoxal phosphate in red blood cells. Pyridoxal phosphate can participate in the normal metabolism of amino acids, carbohydrates and fats. Vitamin B6 is mainly used clinically for the prevention and treatment of vitamin B6 deficiency, prevention and treatment of isoniazid poisoning, seborrheic dermatitis, and chapped lips. It can also be used for vomiting caused by pregnancy, radiotherapy and chemotherapy, and neonatal hereditary vitamin B6 Dependence syndrome.

The symptoms of vitamin B6 deficiency in the human body are:

(1) Skin: When the human body is deficient in vitamin B6, seborrheic skin of the eyes, nose and mouth can appear within a few weeks. Similar skin lesions, often accompanied by glossitis and stomatitis.

(2) Nervous system: Mainly manifested as peripheral neuritis, accompanied by joint swelling and tenderness.

What are the symptoms of vitamin B12 deficiency in the body?

Vitamin B12, also known as cobalamin, is a vitamin containing mineral elements and is not easily absorbed by the body. Vitamin B12 becomes physiologically active only after it is converted into methylcobalamin and coenzyme B12 in the body. The mechanism of action of vitamin B12 is similar to that of folic acid. Deficiency can lead to deoxyribonucleotide synthesis disorders, thereby affecting the maturation of red blood cells and ultimately leading to megaloblastic anemia. Vitamin B12 is mainly used clinically for megaloblastic anemia, neuritis and other diseases caused by vitamin B12 deficiency.

The symptoms of vitamin B12 deficiency in the human body are:

(1) Anemia: When vitamin B12 is lacking, symptoms such as fatigue, weakness, and anorexia will appear early. Hyperbilirubinemia, mild jaundice, and, in severe cases, leukopenia and thrombocytopenia may subsequently occur.

(2) Gastrointestinal symptoms: Some patients may experience anorexia, indigestion, diarrhea, glossitis and other symptoms.

(3) Skin symptoms: can lead to pigmentation of skin and mucous membranes.

(4) Nervous and psychiatric symptoms: Most patients present with numbness of the hands and feet, abnormal sensation or tingling in the extremities, and even abnormal gait, and loss of control of the bladder and anal sphincter. In addition, there is a kind of "megaloblastic dementia", which shows symptoms such as mania, depression, disorientation and memory loss.

It is worth noting that vitamin B12 deficiency is often accompanied by folic acid deficiency, so folic acid should be supplemented at the same time to obtain better curative effects.

Conclusion

When the human body is deficient in vitamin B6 and vitamin B12, supplementing it with food is a simple, effective and safe method. Fruits, nuts, cereals and meats all contain a certain amount of vitamin B6, while meat, fish, shellfish, eggs and dairy products are daily food sources of vitamin B12. If your daily diet cannot meet the body's needs for vitamin B6 and vitamin B12, you can choose to take vitamin B complex medications. It is recommended to consult a physician or pharmacist before taking them.