Abdominal pain, chest and abdomen tingling, heat arthralgia, sore swelling, upset and sleepless; Hepatosplenomegaly, angina pectoris.
Can be used for treating chest pain, hypochondriac pain, rheumatic arthralgia, abdominal mass, sores, traumatic stress, irregular menstruation, amenorrhea, dysmenorrhea, and postpartum stasis pain. It has good curative effect on chest and rib pain, abdominal mass, irregular menstruation and amenorrhea pain, and is often used in combination with Chuanxiong. For pain in chest and abdomen, it belongs to qi stagnation and blood stasis. It is often used with Amomum villosum and Sandalwood.
Can be used for treating epidemic febrile disease, heat entering blood, rash, dizziness, and dysphoria. Often used with fresh rehmannia root, buffalo horn and Scrophularia root.
Used for palpitation and insomnia. It is often used with Ziziphus jujuba seed and Semen Platycladi.
Usage and dosage: decoction, 9 ~ 15g.
Promoting blood circulation and removing blood stasis should be roasted with wine.
Pay attention to anti-veratrum.
Pregnant women should use it with caution. [Adverse reactions] 1) Some patients may have stomach pain, loss of appetite, dry mouth and throat, nausea and vomiting, which is related to the fact that Salvia miltiorrhiza can inhibit the secretion of digestive juice. It is advisable to stop taking drugs, such as metoclopramide and propofol, and atropine can be injected subcutaneously in severe cases. 2) Individual patients with advanced schistosomiasis hepatosplenomegaly will suffer from upper gastrointestinal bleeding after taking large doses of Salvia miltiorrhiza. Salvia miltiorrhiza should be stopped and given hemostatic drugs and vitamins. 3) Salvia Miltiorrhiza can cause allergic reactions, such as itchy skin, rash, urticaria, some accompanied by chest tightness, dyspnea, even aversion to cold, dizziness, nausea and vomiting, irritability, and then pale face, cold sweat on limbs, blood pressure drop, and even syncope and shock. Adrenaline, dexamethasone, phenamine and other antiallergic drugs should be injected immediately and conditioned with Shengmai Powder. Report to the authorities
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Pharmacological study (1) The role of cardiovascular system
①
Strengthening the heart strengthens myocardial contractility, improves cardiac function, and does not increase myocardial oxygen consumption.
②
Effect on blood vessels
Dilating coronary artery and increasing myocardial blood flow; Dilate peripheral blood vessels and increase blood flow; Decreased cerebral blood flow
③
Anti-thrombosis
Improve fibrinolytic enzyme activity; Prolonging bleeding and coagulation time; Inhibit platelet aggregation (increase the level of camp in platelets and inhibit txa2 synthesis); Improve hemorheological characteristics (reduce blood viscosity and shorten erythrocyte electrophoresis time)
④
Improve microcirculation
(b) Promoting tissue repair and regeneration.
①
Promote tissue repair and regeneration
Salvia miltiorrhiza preparation treatment: necrotic myocardium is cleared quickly; Fibroblast differentiation and collagen fiber formation were obvious; Granulation is mature. Local congestion is relieved, blood circulation is improved and healing time is shortened.
②
Inhibit hyperproliferation
It can inhibit the excessive proliferation of fibroblasts. (3) Protect the liver
Improve liver microcirculation.
(4) Antibacterial activity
Salvia miltiorrhiza preparation contains cryptotanshinone and dihydrotanshinone, which have inhibitory effects on staphylococcus, Escherichia coli and denatured bacteria in vitro.