Yes. According to the query related public information shows that grapefruit juice will be oxidized when exposed to air, resulting in the loss of nutrients and changes in taste. This is because grapefruit juice is rich in antioxidant substances such as vitamin C and flavonoids, but these substances will be oxidized and decomposed when exposed to air, thus reducing their antioxidant effect and nutritional value. In grapefruit juice contains beta-carotene and lycopene can antioxidant, help to remove free radicals in the body, improve immunity, delay aging.