There is no difference, almost all medications can be taken with warm or cool water.

Cool water is generally preferred to avoid the breakdown of certain medications in a hot water environment. The normal human oral temperature is 36.2℃~37.2℃, below this temperature is "cool water", close to this temperature is "warm water", higher than this temperature is "hot water". The heat-resistant temperature of the human mouth is 50 ℃ ~ 60 ℃, so, higher than 60 ℃ of water will make people feel "hot".

Water temperature will be affected by the efficacy of common drugs are as follows:

1, live bacterial preparations

According to the instructions, live bacterial preparations should be kept refrigerated, with cool water or warm water (<37 ℃). Therefore, it is best to take the live bacterial preparation with cool water.

2, soft capsule

Soft capsule is a special dosage form, generally need to be in a "cool, dry place" to save, the Pharmacopoeia requires that the storage temperature is 8 ℃ ~ 20 ℃, this environment is most conducive to the stabilization of the soft capsule. This environment is the most favorable for the stability of soft gelatin capsules. High temperature will lead to adhesion between soft gelatin capsules, affecting capsule stability and drug release. Therefore, soft capsules are suitable for delivery with warm and cool water, hot water will increase the viscosity of the capsule shell, making it easy to adhere to the esophageal mucosa thus causing esophageal damage.

3, vitamin C

There are many factors that affect the oxidative decomposition of vitamin C, temperature, light, air exposure. Vitamin C will oxidize and decompose in hot water above 40 degrees Celsius, so vitamin C effervescent tablets should be brewed with cool water. Dry vitamin C doesn't show much oxidative breakdown until it's above 80°C, so vitamin C tablets taken orally don't need to be overly concerned with water temperature.

4, digestive enzymes

The literature reports that sugar-containing pepsin is unstable when exposed to heat, and is prone to decomposition and failure above 70 degrees Celsius. However, there is no need to worry too much about the general delivery of warm water, even with 40 ℃ ~ 60 ℃ of hot water delivery, the extent of the impact on the drug is not great.

Extended information:

How much water to drink also has a relationship with the nature of the drug:

1, never dry swallowing of tablets

This is just like the dry river rowing boat, tablets or capsules are easy to the esophagus in the "The first thing you need to do is to take the pills and swallow them. Usually take the medicine to drink enough 60 to 100 milliliters of water. Some drugs on the esophageal mucosa damage is more obvious, like potassium chloride, aspirin, aminophylline, pau d'arco, anti-inflammatory pain, prednisone, etc., take these drugs should drink more than 200 milliliters of water.

2, taking some drugs should drink more water

such as salt laxatives, antipyretics and sulfonamides should drink as much water as possible. Because, laxatives, antipyretics due to diarrhea or sweat loss of water need to be supplemented. Sulfonamide drugs (sulfadiazine, cotrimoxazole, etc.), due to its metabolites low solubility, easy to precipitate crystals in the urinary tract, resulting in crystalluria, hematuria, dysuria, etc., so it is also necessary to drink more water during the drug, at least 1500 milliliters per day.

3, then there are certain drugs should not drink more water

such as aluminum hydroxide gel, Led gastric, mazurin granules and other gastric drugs, its role is to put a layer of protective film on the gastric mucosa or ulcer surface, so you can not drink too much water.

For example, when taking Mazillin granules, each bag needs only 15-30 ml of water, which is conducive to the formation of a protective effect on the gastric mucosa at a higher concentration.

Smiletta is a digestive mucosal protection agent, has a strong adsorption, the drug can be uniformly covered in the entire surface of the intestinal lumen, in order to adsorption of disease-causing microorganisms, so each bag of 3 grams of only 50 ml of water.

Serving cough syrup is to let part of the medicine stay on the surface of the inflamed pharyngeal mucosa, the formation of a protective film to reduce mucosal inflammation, blocking irritation, relieve coughing, and water will dilute the medicine, weakening the effect of coughing, so don't drink water within 5 minutes of drinking the syrup.

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