Osteosarcoma is one of the most common malignant bone tumors, which often occurs in teenagers. The most common parts are the distal femur, the proximal tibia and the proximal humerus metaphyses, forming a spindle, which may involve periosteum, cortical bone and medullary cavity. The cut surface of the lesion is fish-shaped, medium red or grayish white. Fibrosarcoma of bone is a rare malignant tumor, which originates from non-osteogenic fibrous tissue and connective tissue. It mainly occurs in the metaphysis and diaphysis of long bones of limbs, especially femur. These are two completely different diseases.

Osteosarcoma accounts for 1 or the second place of primary malignant bone tumor, and its malignancy is very high, which is very harmful to the quality of life and even life of patients, and should be paid great attention to. The earliest symptom of this disease is persistent pain. At this point, the lesion may have lasted for some time. Many patients always understand the pain around the joint as a joint sprain until they have persistent pain or touch a lump. Therefore, the focus of population prevention should be the popularization of relevant knowledge, so that people can increase their knowledge and understanding of osteosarcoma and improve their vigilance. The improvement of sanitary conditions and medical quality is the guarantee of early detection, and the popularization of crowd knowledge is the basis of early detection. Therefore, it should be emphasized that when teenagers find pain around their knees without obvious trauma, they should go to a hospital with a certain level at an early stage to facilitate early detection and treatment, improve the survival rate and benefit the people.