Contents 1 Pinyin 2 English reference 3 Overview 4 "Ti Ren Compilation" Volume Liufang Baizi Yangxin Pills 4.1 Alias ??of Baizi Yangxin Pills 4.2 Composition 4.3 Usage and dosage of Baizi Yangxin Pills 4.4 Efficacy and indications 5 Volume 70 of "Encyclopedia of Ancient and Modern Medical Traditions" cites "Collected Prescriptions" of Baizi Yangxin Pills 5.1 Prescription name 5.2 Composition 5.3 Indications 5.4 Usage and dosage of Baizi Yangxin Pills 5.5 Preparation method 5.6 Note 6 "Complete Records of the Ministry of Medicine" Volume 331 Baizi Yangxin Pills 6.1 Prescription Name 6.2 Composition 6.3 Efficacy 6.4 Usage and Dosage of Baizi Yangxin Pills 6.5 Preparation Method 7 Baizi Yangxin Pills 7.1 Composition of "National Formulary of Traditional Chinese Medicines" (Beijing, Chengde) 7.2 Usage and dosage of Baizi Yangxin Pills 7.3 Efficacy and indications 8 Pharmacopoeia standards of Baizi Yangxin Pills 8.1 Product name 8.2 Prescription 8.3 Preparation method 8.4 Properties 8.5 Identification 8.6 Inspection 8.7 Function and indications 8.8 Usage and dosage 8.9 Specifications 8.10 Storage 8.11 Version 9 Baizi Yang Instructions for the drug of Baixin Pill 9.1 Drug name 9.2 Chinese Pinyin of the drug 9.3 Dosage form 9.4 Properties 9.5 Main ingredients of Baizi Yangxin Pill 9.6 Function and indication of Baizi Yangxin Pill 9.7 Usage and dosage of Baizi Yangxin Pill 9.8 Precautions 10 References attached: 1 Ancient books Seminis Biotae Pill for Nourishing Heat [Xiangya Medical Professional Dictionary]
baizi yangxin pills [Traditional Chinese Medicine Terminology Approval Committee. Traditional Chinese Medicine Terminology (2004)]
baizi yangxin wan [Traditional Chinese Medicine Terminology Approval Committee. Terminology of Traditional Chinese Medicine (2004)]
3 Overview
Baizi Yangxin Pill is the name of a prescription, and there are about 4 prescriptions with the same name.
The main ingredients of the Chinese patent medicine Baizi Yangxin Pills are Baiziren, Codonopsis pilosula, Astragalus membranaceus, Chuanxiong, Angelica sinensis, Poria cocos, Polygala root (made), Ziziphus kernel, cinnamon, Schisandra chinensis (steamed), Pinellia ternata, Zhigancao, cinnabar [1]. It has the effects of nourishing qi, nourishing blood and calming the mind. It is used for deficiency and cold heart qi, palpitations and easy fright, insomnia, dreaminess, and forgetfulness.
"The Pharmacopoeia of the People's Republic of China" (2010 edition) records the pharmacopoeial standards of Baizi Yangxin Pills. 4 "Tiren Compilation" Volume Liufang Baizi Yangxin Pills 4.1 Alias ??of Baizi Yangxin Pills
Baizi Yangxin Pills[2]. 4.2 Composition
Four liang of Bai Ziren, three liang of Lycium barbarum, one liang each of Ophiopogon japonicus, Angelica sinensis, Acorus calamus, and Fushen, two liang each of Scrophulariaceae and Rehmannia glutinosa, and five qian licorice [2]. 4.3 Usage and dosage of Baizi Yangxin Pills
Take powder, refine honey into pills, and take 40 to 50 pills each time [2]. 4.4 Efficacy and Indications
Functions: nourish the heart and calm the mind, nourish the kidneys and nourish yin [2].
Treats deficiency of nutrients and blood, disorders of the heart and kidneys, trance, palpitations, sleeplessness, forgetfulness and night sweats [2]. 5 Baizi Yangxin Pills 5.1 from "Collected Prescriptions" cited in Volume 70 of "Ancient and Modern Medical Traditions". Prescription name
Baizi Yangxin Pills 5.2 Composition
Baiziren (fresh white but not smoked) If it is hot, beat it with a paper bag to remove the oil) 2 liang, white Poria Shen 2 liang, jujube kernels 2 liang, Schisandra chinensis half a liang, Angelica sinensis 2 liang, raw rehmannia glutinosa 2 liang, licorice half a liang, cinnabar (finely grind) half a liang, Rhino horn (pound) half a tael. 5.3 Indications
Volume 70 of "Encyclopedia of Ancient and Modern Medical Traditions" cites Baizi Yangxin Pills from "Collected Prescriptions", which is mainly used to treat excessive mental fatigue, lack of concentration, dreams when eyes are closed, and infrequent discharge. 5.4 Usage and Dosage of Baizi Yangxin Pills
Take 1 pill each time and chew it in the afternoon or when lying down. 5.5 Preparation method
The upper part is the powder, and the refined honey is made into pills, which are as big as gorgon seeds, and the gold foil is made into pellets. 5.6 Notes
"Wan San Yu Dan Ji Ji" contains Huang Qi. It can be used to treat blood deficiency and internal heat, insomnia and palpitations, as well as omenorrhea, weight loss and hot flashes in women. 6. Volume 331 of "Comprehensive Records of the Ministry of Medicine" quoted from "Tiren Collection" Baizi Yangxin Pill 6.1 Prescription name
Baizi Yangxin Pill 6.2 Composition
Baiziren (steamed, Sun-dried and shelled) 4 taels, wolfberry (washed in wine and dried) 3 taels, Ophiopogon japonicus (heart removed) 1 tael, Angelica sinensis (soaked in wine) 1 tael, Acorus calamus (hairless, washed) 1 tael, Poria Shen (peeled and heart removed) 1 tael, Rehmannia glutinosa (steamed with wine) 2 taels, Yuanshen 2 taels, licorice (coarse skin removed) 5 qian. 6.3 Efficacy
"The Complete Records of the Ministry of Medicine" Volume 331 quoted from "Tiren Collection", Baizi Yangxin Pills have the functions of calming the heart and protecting the body, benefiting the blood and strengthening essence, dispelling irritability, heat and palpitation, and keeping the mind from forgetting. effect. 6.4 Usage and dosage of Baizi Yangxin Pills
Take 4050 pills each time and give it as white soup before going to bed. 6.5 Preparation method
Take the powder above, remove the cypress kernels and cooked rehmannia glutinosa, steam them, pound them into mud in a stoneware, mix the rest of the medicine into powder, add refined honey to make pills, as big as sycamore seeds. 7. Baizi Yangxin Pills 7.1 in the "National Formulary of Traditional Chinese Medicines" (Beijing, Chengde) Composition
7.5g each of Baiziren, Polygala, Ziziphus seed, Schisandra chinensis, ginseng, cinnamon, 60g Poria, Ligusticum chuanxiong, 30g each of Astragalus membranaceus, Angelica sinensis, and Pinellia ternata, and 3g licorice [2]. 7.2 Usage and dosage of Baizi Yangxin Pills
It is made into fine powder, refined honey is made into pellets, and cinnabar is made into clothes. Take 9g each time, 2 times a day [2]. 7.3 Efficacy and indications
Functions: nourish qi and blood, strengthen the heart and calm the mind [2]. Treats loss of effort, confusion, palpitations, insomnia and forgetfulness [2]. 8 Pharmacopoeia standard 8.1 of Baizi Yangxin Wan
Baizi Yangxin Wan
Baizi Yangxin Wan 8.2 Prescription
Baiziren 25g, Codonopsis pilosula 25g, Zhihuangqi 100g , Ligusticum chuanxiong 100g, angelica 100g, poria 200g, polygala 25g, jujube kernel 25g, cinnamon 25g, vinegar schizandra 25g, pinellia koji 100g, licorice 10g, cinnabar 30g 8.3 Preparation method
The above thirteen flavors , cinnabar water flies into very fine powder; the remaining cypress seeds and other twelve flavors are crushed into fine powder, grind with the above powder, sieve and mix. For every 100g of powder, add 25 to 40g of refined honey and appropriate amount of water to make water honey pills and dry; or add 100 to 130g of refined honey to make small honey pills or large honey pills. 8.4 Properties
This product is brown water honey pills, brown to tan small honey pills or large honey pills; the taste is sweet at first and then bitter and slightly numb. 8.5 Identification
(1) Take this product and observe it under a microscope: the irregular branched clumps are colorless and dissolve when exposed to chloral hydrate test solution; the hyphae are colorless or light brown, with a diameter of 4~ 6μm (Poria cocos).
The thin-walled cells are spindle-shaped, with slightly thick walls and extremely fine diagonal staggered textures (Angelica sinensis). The fibers are bundled or scattered, the wall is thick, there are longitudinal cracks on the surface, and the two ends are broken into broom-like or relatively flat sections (burned astragalus). The parenchyma cells around the fiber bundles contain calcium oxalate square crystals, forming fine fibers (Glycyrrhiza uralensis). The stone cells are round or square, 32 to 88 μm in diameter, with thin walls (cinnamon) on one side. The epidermal stone cells of the seed coat are light yellowish brown, with a quasi-polygonal surface appearance, thick walls, fine pores and grooves, and a dark brown substance (vinegar Schisandra chinensis) in the cell cavity. The endotesta cells are yellow, rectangular or polygonal in surface view, and have microwave-like curved walls (Bai Ziren). The endotesta cells are brownish-yellow, rectangular or quasi-square in surface appearance, and the vertical wall is thickened in a bead-like manner (Zoozao Seed). The connecting milk ducts are 12 to 15 μm in diameter and contain fine particles (Codonopsis pilosula). Calcium oxalate crystals are in the shape of round clumps or clusters and are found in parenchyma cells (Ligusticum chuanxiong). Calcium oxalate needle crystals are in bundles, 32 to 144 μm long, and are present in mucus cells or scattered (Panalia qu). Irregular fine particles are brownish red, shiny, with dark black edges (cinnabar).
(2) Take 12g of this product's water honey pills and grind them; or take 18g of small honey pills or large honey pills, cut them into pieces, add 10g of diatomaceous earth, and grind them evenly. Place it in a Soxhlet extractor, use ether to reflux and extract until the extract is nearly colorless, evaporate the ether in the residue, and extract with an appropriate amount of methanol until the extract is nearly colorless. Recover the methanol from the extract until it is dry. Add 40 ml of water to the residue to dissolve it. , shake and extract with water-saturated n-butanol 4 times, 30ml each time, combine the n-butanol extracts, wash with ammonia test solution 3 times, 40ml each time, discard the washing liquid, evaporate the n-butanol liquid to dryness, and add Dissolve 10 ml of 40 methanol, add it to a neutral alumina column (80 mesh, 5g, inner diameter 1.5cm), elute with 150 ml of 40 methanol, collect the eluate, evaporate to dryness, add 1 ml of methanol to the residue to dissolve, and use it as a supply Test solution. Take another astragaloside IV reference substance, add methanol to make a solution containing 1mg per 1ml, and use it as the reference substance solution. According to the thin layer chromatography test (Appendix VI B of Pharmacopoeia 2010 Edition), draw 5 μl of each of the above two solutions, respectively point on the same silica gel G thin layer plate, and use chloroform-methanol-water (13:7:2 ) is the developing agent, unfold, take out, dry, spray with 10% sulfuric acid ethanol solution, heat at 105°C for about 5 minutes, and inspect under sunlight and ultraviolet light (365nm) respectively. In the chromatogram of the test product, at the position corresponding to the chromatogram of the reference substance, spots of the same color appear under sunlight; fluorescent spots of the same color appear under ultraviolet light.
(3) Take 12g of this product's water honey pills and grind them; or take 18g of small honey pills or large honey pills, cut them into pieces, add 10g of diatomaceous earth, and grind them evenly. Add 50 ml of diethyl ether and 10 ml of ammonia test solution, shake well, leave it for 24 hours, filter, evaporate the filtrate to dryness, add 1 ml of absolute ethanol to the residue to dissolve, and use it as the test solution. Take another 1g of Chuanxiong reference medicinal material, add 10ml of diethyl ether and 2ml of ammonia test solution, and prepare the reference medicinal material solution in the same way. According to the thin layer chromatography test (Appendix VI B of the 2010 edition of the Pharmacopoeia), draw 10 μl of each of the above two solutions and spot them on the same silica gel G thin layer plate prepared with 1 sodium hydroxide solution. Use petroleum ether (30~ 60℃)-chloroform (1:1) as the developing agent, unfold, take out, dry, and spray with dilute bismuth potassium iodide test solution. In the chromatogram of the test product, spots of the same color appear at the positions corresponding to the chromatogram of the control medicinal material.
(4) Take 2.5g of this product’s water honey pills and grind them; or take 2.5g of small honey pills or large honey pills, cut into pieces, add an equal amount of diatomaceous earth, grind evenly, add 50ml of methanol, Ultrasonicate for 30 minutes, let cool, shake well, filter, and take the remaining filtrate as the test solution. Take another cinnamaldehyde reference substance, add methanol to make a solution containing 2 μg per 1 ml, and use it as the reference solution. According to the test of high performance liquid chromatography (Appendix VI D of Pharmacopoeia 2010 edition), octadecylsilane bonded silica gel is used as the filler, and acetonitrile-water (30:70) is used as the mobile phase; the detection wavelength is 290nm, theoretically The number of plates calculated based on the cinnamic aldehyde peak should be no less than 5,000. Take 10 μl of each of the above two solutions and inject it into the liquid chromatograph. In the chromatogram of the test product, there should be a chromatographic peak with the same retention time as the chromatographic peak of the reference substance.
8.6 Inspection
It should comply with the relevant regulations under pills (Appendix I A of the 2010 edition of the Pharmacopoeia). 8.7 Functions and Indications
Reinforcing Qi, nourishing blood, and calming the mind. It is used for deficiency and cold heart qi, palpitations and easy fright, insomnia, dreaminess, and forgetfulness. 8.8 Usage and Dosage
Take orally. Water honey pills are 6g at a time, small honey pills are 9g at a time, and big honey pills are 1 pill at a time, twice a day. 8.9 Specifications
Each pill of Dami Pills weighs 9g. 8.10 Storage
Sealed. 8.11 version
"Chinese Pharmacopoeia" 2010 Edition 9 Baizi Yangxin Pills Instructions 9.1 Drug Name
Baizi Yangxin Pills 9.2 Drug Chinese Pinyin
Baizi Yangxin Wan 9.3 Dosage Form
Damee Pills: Each pill weighs 9g. 9.4 Properties
Baizi Yangxin Pills are brown water honey pills, brown to tan small honey pills or large honey pills; the taste is sweet at first and then bitter and slightly numb. 9.5 The main ingredients of Baizi Yangxin Pills
Baiziren, Codonopsis pilosula, Astragalus membranaceus, Ligusticum chuanxiong, Angelica sinensis, Poria cocos, Polygala root (made), Ziziphus kernel, cinnamon, Schisandra chinensis (steamed), Pinellia qu, Zhigancao , cinnabar. 9.6 Functions and Indications of Baizi Yangxin Pills
Replenishing qi, nourishing blood, and calming the mind. It is used for deficiency and cold heart qi, palpitations and easy fright, insomnia, dreaminess, and forgetfulness. 9.7 Usage and dosage of Baizi Yangxin Pills
Shuimi Pills are 6g each time, Xiaomi Pills are 9g each time, and Dami Pills are 1 pill each time; 2 times a day. 9.8 Precautions
1. It is contraindicated for those with excessive liver yang.