Quinine contained in bitter gourd has the side effect of stimulating uterine contraction and causing abortion. Pregnant women should eat less bitter gourd. Bitter gourd is cold, but children's gastrointestinal function is weak. Long-term consumption of bitter gourd will affect children's appetite. In addition, bitter gourd also contains an insulin-like substance called "polypeptide-P", which has the function of lowering blood sugar, and people with hypoglycemia should not eat bitter gourd in large quantities for a long time.

If it weren't for the above people, eating more bitter gourd wouldn't do any harm.