This kind of allergic reaction has no rash, only acupuncture and severe itching, but also red wind masses of about 2 mm can appear on the skin near the trunk and limbs (except armpits and palms and soles). This kind of wind mass comes quickly and leaves no trace. Mild cholinergic urticaria can occur in adolescence of ordinary people. Generally, after stopping exercise or calming down, the symptoms can subside, so it is not easy to attract attention. The whole process can range from months to years, and those with frequent attacks should go to dermatology for diagnosis and treatment in time. After treatment with antihistamines and anticholinergic drugs, the condition can be alleviated or alleviated.
Mental stress, body heat or exercise can often induce skin lesions. The biggest clinical feature of the disease is that the wind mass damage is quite small, about1~ 3 mm, and the surrounding area is flushed, which is extremely itchy and often accompanied by headache, dizziness, salivation, sweating and other symptoms. Satellite-like wind masses can sometimes be seen. The intradermal test with1:5000 acetylcholine can be positive, that is, intense erythema appears. This type of palmoplantar is usually not involved, and the disease can recur for months or years.
Six suggestions for patients with cholinergic urticaria.
1, pay attention to diet and avoid incentives. The incidence of urticaria has a certain relationship with diet, and some foods may be the inducement. For example, fish, shrimp and seafood, canned food containing artificial additives such as artificial pigments, preservatives and yeasts, preserved food and beverages can all induce urticaria. In addition, irritating foods such as too hot and sour will also reduce the digestive function of the gastrointestinal tract, making food residues stay in the intestine for too long, thus producing peptones and peptides, increasing the probability of human allergies.
2. Pay attention to hygiene and avoid bad stimulation. People with a history of urticaria should pay attention to keeping indoor and outdoor cleanliness, and keep fewer pets such as cats and dogs at home. Avoid inhaling pollen, dust, etc. Avoid wind, cold, summer, dampness, dryness, fire and insect poison. Adapt the law of life to the changes in the external environment. Drinking, heating, emotional excitement, exertion, etc. will aggravate skin vasodilation and stimulate or aggravate urticaria. Rubber gloves, hair dye, perfumed soap and detergent, chemical fiber and wool clothing may all be bad stimuli for people with allergies or urticaria and should be avoided. People suffering from cold urticaria should not go to the bathing beach or take a cold bath. Pay attention to keep warm in winter. Cholinergic urticaria should keep the body cool and avoid sweating. According to relevant research, the positive rate of IgE in blood and skin test of smokers is obviously higher than that of non-smokers, and the allergic phenomenon caused by passive smokers such as their children is also relatively increased. Therefore, people with urticaria should quit smoking.
3, pay attention to allergies caused by drug factors. In clinic, some drugs can cause urticaria, such as penicillin, tetracycline, chloramphenicol, streptomycin, sulfonamides, polymyxin and other antibiotics, analgin, aspirin and other antipyretic and analgesic agents. Some Chinese patent medicines, such as Ganmaoqing and Niuhuang Jiedu tablets, can also cause allergies and urticaria. When you are taking a variety of drugs and suspect that urticaria is caused by one of them, the simplest and most effective way is to stop taking the drugs in time.
4. Actively treat the original diseases. Urticaria is not only an independent disease, but also a skin manifestation of some diseases. There are many diseases that can lead to urticaria, such as infectious diseases: parasitic infections such as intestinal roundworms and pinworms; Bacterial infections such as dental caries, alveolar abscess, tonsillitis, otitis media, sinusitis, etc. Viral infections like hepatitis B; Fungal infections such as tinea of hands and feet. In addition, diabetes, hyperthyroidism, menstrual disorders, and even potential tumors in the body may cause urticaria. Therefore, effective diagnosis and treatment of the original diseases will help to eliminate urticaria.
5. Maintain a healthy attitude and improve physical resistance. The attack and aggravation of chronic urticaria have a certain relationship with people's emotional or psychological stress. Traditional Chinese medicine has the theory of "being indifferent and nihilistic, being safe from illness" in preventing and treating diseases. It holds that keeping a pure mind and lacking desires can make the human body's qi flow harmoniously, the blood vessels flow smoothly, and the healthy qi is abundant. Over time, urticaria will naturally disappear invisibly.
6, anti-allergic probiotics. Xinminkang anti-allergic probiotics can participate in IgE-mediated immune allergic reaction. By measuring that human dendritic cells can produce organic acids, free fatty acids, hydrogen peroxide and bacteriocin after co-culture with anti-allergic probiotics, the growth of other harmful bacteria can be inhibited. After "biological oxygen deprivation", aerobic pathogenic bacteria are greatly reduced, and probiotics can colonize mucosa, skin and other surfaces or cells to form biological barriers, which can hinder the colonization of pathogenic microorganisms and play a role in occupying space, robbing nutrients, and benefiting each other. Xinminkang, an antiallergic probiotic, can also affect the nonspecific immune function of the body, thereby naturally killing the activity of NK cells, enhancing the excretion of immunoglobulin IgA, and improving the barrier function of skin appearance or cells. Can effectively treat various types of allergies, including urticaria, allergic rhinitis, conjunctivitis, atopic dermatitis, allergic asthma, food, pollen and other allergic symptoms.
7. Cholinergic urticaria: In addition to routine antihistamines, atropine, propofol and reserpine are often added to get satisfactory results.