Agrimonia pilosa is one of the commonly used Chinese medicines. The research shows that the whole grass of Agrimonia pilosa contains n-nonacosane, β-sitosterol, caffeic acid, ellagic acid, catechin, etc. besides Agrimonol A, Agrimonol B, Agrimonol C, Agrimonol D, Agrimonol E and Agrimonolide. Has insecticidal (schistosome, tapeworm and ascaris lumbricoides), spermicidal, hemostatic and antitumor effects. Clinically, it is mainly used for schistosomiasis, taeniasis and ascariasis; Family planning, birth control and contraception can be made into external suppository and effervescent tablet for vaginal administration to achieve the purpose of contraception. In the aspect of anti-tumor, it is mainly achieved through the gap between nuclear membranes. At the same time, agrimony is also used for many kinds of hemorrhagic diseases. Its decoction and agrimony have cardiotonic effects on isolated frog hearts, while the alcohol extract has inhibitory effects. Agrimonia pilosa is cheap and easy to get, and has many clinical uses, but its compound preparation is few, which needs further development and research.