Gout is a metabolic syndrome, mainly due to a decline in uric acid excretion in the body, or the body's purine metabolism is abnormal, resulting in high levels of uric acid in the blood, so that urate crystals precipitate around the joints. Gout has a long course and is divided into four periods.
One, the period of no signs
The pre-symptoms of gout are the same as in normal people, except that the uric acid in the serum is elevated.
So, nowadays, gout is not really gout, but a kind of hyperuricemia.
This period of time can be years, decades, and possibly a lifetime, and in some patients it can develop into kidney stones, arthritis, and so on.
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Two, the acute phase of gout.
If the condition continues to deteriorate and the uric acid level in the patient's body is high, it may develop into acute arthritis and early gout;
At this time, the patient tends to suffer from hot and swollen joints of the feet, intolerable pain, difficulty in moving, and it also spreads to the toes, ankles, dorsum of the feet, heels and other parts of the feet, and the symptom occurs mostly at night. The patient can't even wear shoes and must lie in bed all day.
Three, gout intermittent period.
After the gout lasts for a period of time, there will be an intermittent state, in which the symptoms of gout will be significantly relieved, but will recur soon afterward, and some people will have many repeated attacks in their whole life.
In this case, the site of gout develops from single-jointedness to multi-jointedness, which may affect all the joints of the body, causing damage to the soft tissues and bones around the joints and leading to a slight decline in kidney function.
Fourth, the chronic flare-up of the disease.
With the progress of the disease, the symptoms of gout will gradually aggravate, the deposition and increase of gout stones, the whole body joints are swollen, pain, heat, distension, and even ulcers and deformities.
In addition, hyperuricemia has a great impact on the patient's renal function, which can cause a series of complications, such as chronic arthritis, chronic interstitial nephritis, uremia and renal failure, at this time, the patient is already life-threatening.
Gout is a disease that requires long-term treatment, it is prone to recurrent attacks, it is difficult to completely cure, and has a certain heredity. In recent years, the number of gout patients in China has been increasing, which needs to be taken seriously.
Risk factors for gout include obesity, alcohol consumption, high blood pressure, high blood sugar, and high purine content in the diet.