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Introduction of Hemp Seed Pills
Table of Contents 1 Pinyin 2 English Reference 3 General Introduction 4 Ma Zi Ren Wan (麻子仁丸), a formula from "The Treatise on Typhoid Fever" (伤寒论) for the diagnosis of yangming disease (阳明病). 4.1 Alias of Ma Zi Ren Wan (麻子仁丸) 4.2 Prescription 4.3 Method of Preparation 4.4 Efficacy and Indications 4.5 Usage of Ma Zi Ren Wan (麻子仁丸). 4.6 Formulas and Explanations 4.7 Clinical Use 4.7.1 Methods of Addition and Subtraction 4.7.2 Taboos of Use 4.8 Contraindications for Use 4.8. 4.8.3 Post-partum constipation 4.8.4 Others 4.9 Pharmacological effects of Ma Zi Ren Wan 4.9.1 Effects on liver, gallbladder and gastrointestinal functions 4.9.2 Effects on heart, circulatory system and blood rheology 4.9.3 Antipathogenic microorganisms 4.9.4 Effects on immune functions 4.9.5 Anti-inflammatory, antioxidant and antiallergenic effects 4.10 Songs and phrases 4.11 Sources 5 Ma Zi Ren Wan Drug Instruction 5.1 Drug Description 5.1 Ma Zi Ren Wan Drug Instruction 5.1 Additions and Additions 4.7 Contraindications 4.7 Contraindications for Use Maziren Wan 5.1 Name of the Medicine 5.2 Classification 5.3 Formulations 5.4 Main Ingredients of Maziren Wan 5.5 Pharmacological Actions of Maziren Wan 5.6 Functions and Indications of Maziren Wan 5.7 Dosage and Administration of Maziren Wan 5.8 Precautions 5.9 Comments 6 References Attachment 1 Maziren Wan in Ancient Texts 1 Pinyin

má zǐ rén wán

2 English Reference

Maziren Wan [21st Century]. Maziren Wan [21st Century Bilingual Dictionary of Science and Technology]

maziren pills [Nomenclature Review Committee of Chinese Medicine. Nomenclature of Chinese Medicine (2004)]

3 Overview

Maziren Pills is recorded in the Treatise on Typhoid Fever, which consists of 500g of maziren, 250g of peony, 250g of citrus aurantium, 500g of rhubarb, 250g of thick park, 250g of apricot, and 250g of almonds, which is effective in moistening the intestines and draining heat and moving the qi to pass stools, and it is mainly used in the treatment of the spleen syndrome due to the dryness of heat in the stomach and intestine, the insufficiency of spleen and fluid, and the obstruction of qi. Habitual constipation, drug constipation, post-partum intestinal constipation, also used for *** disease pain and bleeding caused by dry stools after surgery identification belongs to the intestines and stomach dry heat, fluid deficiency.

4 "Typhoid Fever" identification of Yangming disease pulse evidence and treatment formula of hemp seed kernel pill

The formula laxative, laxative effect can be said to be a symptomatic treatment, so that constipation is immediately improved, but its regulation of cardiac vascular, blood rheology, improve rectal cushion venous circulatory disorders, anti-infective, anti-inflammatory, to improve the maternal post-partum infections and inflammation of the birth canal lacerations, regulating immune function is the root of the treatment, which is the Chinese medicine. This is the so-called traditional Chinese medicine, both the treatment of the root cause and the treatment of the symptoms. [1]

4.1 Synonyms of Hemp Seed Ren Pills

Hemp Seed Ren Pills (《类證活人书》卷十五), Spleen About Hemp Seed Ren Pills (《太平惠民和剂局方》卷六), Hemp Seed Ren Nourishing the Spleen Pills (麻仁滋脾丸)[2], and Spleen About Pills (脾约丸)[2].

4.2 Prescription

Two liters of hemp seed kernel, half a catty of peony, half a catty of Citrus aurantium (sizzling), one catty of rhubarb (peeled), one foot of Houpao (sizzling, peeled), and one liter of almonds (peeled and tipped, boiled, and not made into fat) [3].

hemp seed kernel two liters, peony half a catty, Citrus aurantium (roasted) half a catty, rhubarb (peeled) a catty, thick Park (roasted, peeled) a foot, almonds (peeled tip, fried) a liter [2].

麻子仁500g 芍药250g 枳实250g(炙)大黄500g(去皮)厚朴250g(炙,去皮)杏仁250g(去皮、尖,熬,别作脂)

麻子仁500g、芍药250g、枳实250g、大黄500g、厚朴250g、杏仁250g[4]

麻子 Ren 20g, Paeonia lactiflora 9g, Citrus aurantium dulcis 9g, Rheum palmatum 12g, Magnolia officinalis 9g, almonds 10g[5]

4.3 Method of Preparation

The above is minced, and made into pills of condensed honey as big as a sycamore seed[3].

6 flavors for the end of the honey as pills, such as a sycamore seed large, 10 pills each time, 3 times a day, gradually increase the amount, to the extent that the soft stools are easy to discharge. [5]

4.4 Efficacy and Indications

"Typhoid Fever" of hemp seed kernel pill has the efficacy of moistening the intestines and draining the heat, moving the qi to pass the bowels. It can be used to treat spleen contraction due to dryness and heat in the intestines and stomach, insufficiency of spleen and fluid, and obstruction of qi. Symptoms include dryness and heat in the intestines and stomach, insufficiency of fluid, constipation, frequent urination, distension of the epigastrium and abdomen, thirst and bad smell of the mouth, with a red tongue, thin yellow fur, and number of pulses [4].

Ma Zi Ren Wan functions to moisten the intestines and laxative [2]. It treats the spleen about, hard stools, counting of urine, floating and astringent pulse in the tarsus [2].

4.5 Usage and dosage of Ma Zi Ren Pill

Drink ten pills, three times a day, gradually increased to know the extent[3]

The medicine is ground into powder, and made into pills with condensed honey. 9g each time, 1 to 2 times a day, warm water. It can also be made into soup, and the dosage is reduced according to the proportion of the original formula. [4]

4.6 Explanation of the formula

Ma Zi Ren Wan treats the evidence of spleen about. It is caused by dryness and heat in the intestines and stomach, and insufficient spleen fluid. Spleen for the stomach line its fluid, now dry heat in the stomach, the spleen is constrained, fluid can not be four cloth, but lose bladder, so frequent urination; dry heat injuries, intestinal loss of moistening, then constipation. The treatment is to moisturize the intestines and diarrhea heat, and to move the qi to pass stools. [6]

The formula is heavy with hemp seed kernel texture moist and fat, nourishing the spleen and intestines, moistening dryness and laxative as the monarch drug. Rheumatism is bitter and cold to drain the heat, attack the accumulation of laxative; almonds, lung lowering the gas, moistening dryness and laxative; white peony nourishing Yin convergence of fluid, soften the liver and the spleen, *** for the subject medicine. Citrus aurantium under the gas to break the knot, thick Park to move gas in addition to full, in order to strengthen the power of descending and excreting laxative, used as a support. Make honey to moisten the dryness of the intestines, and harmonize the medicines. Looking at the whole formula, the heavy use of hemp seed kernel nourish the spleen and lubricate the intestines, with rhubarb, Citrus aurantium dulcis, thick Park to drain heat and stagnation, the composition of the attack and moist with the agent. So that the internal organs gas smooth, sufficient fluid, the next does not hurt the positive, the main treatment of spleen and Jin insufficient, intestinal and gastrointestinal dryness and heat of the spleen about the evidence. [6]

Hemp seed kernel pill is small Chengqi Tang plus hemp kernel, almonds, white peony, honey and become. Although also use small Cheng Qi Tang diarrhea stomach dry heat stagnation, but the actual serving size is less, and more to take the quality of the wet more fat hemp kernel, almonds with honey, white peony, can benefit from the yin moistening dryness in order to laxative, but also slow down the small Cheng Qi Tang attack and attack the power to make the next does not hurt the right, and the formula is only 10 pills, the dosage gradually increased, all show that this formula is intended to moisten the intestines and diarrhea, and is the slow down the agent. [6]

Hemp seed kernel pill in the formula of hemp kernel texture moist lipid, laxative; almonds to lower the gas laxative; peony yin and Li; rhubarb, thick park, hedge hedgehog (i.e., a small Chengqi Tang) drain heat stagnation; honey lubricate dryness and slippery intestines [2]. Combined into a pill, it has the functions of moistening the intestines, laxative, and slowing down the bowel[2]

4.7 Clinical Use

Ma Zi Ren Wan is a commonly used formula for the treatment of constipation due to stomach heat and dryness of the intestines. Whenever there is constipation, frequent urination, or epigastric distension, pain in the abdomen, thirst and halitosis, red tongue, thin yellow moss, and number of pulses, this formula can be used with additions and subtractions. [4]

4.7.1 Addition and subtraction

If the dry heat of the stomach and intestines see bleeding hemorrhoids, add acacia flowers, ground elm; hemorrhoids constipation, add peach kernel, Angelica sinensis; injury to the fluid is very serious, the tongue is red with little moss, add the raw land, XuanShen, Maidong, etc.; stools are dry and hard, can be added with manganese nitrate in order to soften and disperse the knot, diarrhea and laxative heat. [4]

4.7.2 Contraindications

Pregnant women, the elderly and people with constipation due to blood deficiency and fluid deficiency should be cautious in the use of Ma Zi Ren Wan [4].

4.8 Modern indications

Ma Zi Ren Wan is commonly used in modern times for habitual constipation, the elderly and postpartum constipation [7].

4.8.1 Habitual constipation

Habitual constipation is defined as dry and hard stools that are secret and difficult to pass. The common cause of simple constipation is a small amount of diet, and less slag, digestive juices are absorbed by the intestinal tract; the food composition is not reasonable, containing more protein and less carbohydrates, the intestinal flora of the intestinal contents of the fermentation of the role of the reduction of the bowel has been alkaline; or the food of the vegetable is less, too little fiber; in addition, malnutrition or intestinal muscle tone is reduced, the contractility of the contraction force is reduced, peristaltic slow powerlessness, prone to constipation; rickets, Hypercalcemia, dermatomyositis, cretinism, congenital myasthenia gravis, etc. also often due to intestinal wall muscle weakness, dysfunction and constipation; anal fissure, *** stenosis, spina bifida, or tumor compression of the cauda equina and so on can cause constipation; some drugs such as anticholinergic drugs, antacids, some anticonvulsant drugs, diuretics, iron, etc. can also make the intestinal peristalsis reduce and trigger constipation; irregular life, mental ***, immune deficiency, defecation, etc. are also cause constipation. Irregular life, mental ***, low immune function, defecation is also a common cause of constipation, its **** the same mechanism are intestinal peristalsis dysfunction, intestinal water absorption and secretion of reduced. [7]

4.8.2 Geriatric constipation

The elderly due to age factors, metabolic function is weakened, intestinal peristalsis and absorption dysfunction, cardiac and circulatory dysfunction, intestinal circulatory insufficiency, peristalsis and secretion can also be limited, the elderly renal deficiency is mainly manifested in the loss of fluids and functional failure, which is commonly seen in the geriatrics, especially drinking less water, physical weakness, less exercise. The elderly is even more so. [7]

4.8.3 Postpartum constipation

Postpartum constipation is mostly due to *** and perineal lacerations during labor, and if it reaches the third degree of laceration, it damages the *** external sphincter, and if it reaches the fourth degree, it damages the rectal *** septum, the mucous membranes of the rectal wall, and it can also be attributed to puerperal infections, especially pelvic inflammatory disease and pelvic thrombophlebitis, which makes the subrectal veins stagnant, and the reflux is impeded, and the postnatal exhaustion, the intestinal peristalsis, and abnormal intestinal absorption function, which can lead to the death of the patient and the death of the patient. The result is constipation. [7]

4.8.4 Others

Often used in the treatment of pain and bleeding caused by dryness of stool after surgery for *** diseases. [7]

4.9 Pharmacological effects of hemp seed kernel pills

[8]

4.9.1 Effects on liver and gallbladder and gastrointestinal function

The Chinese medicinal herb hemp seed kernel contains fatty oil, which has the effect of lubricating the intestinal tract, and at the same time, it produces fatty acids in the intestinal tract after encountering alkaline intestinal fluids *** intestinal wall, so that intestinal peristalsis is strengthened, and its alcoholic extracts have the effect of promoting the secretion of bile and anti-ulcer effect. The aqueous extract of Paeonia lactiflora and the total glucoside of Paeonia lactiflora have obvious protective effect on liver injury, meanwhile, it reduces the degeneration and necrosis of hepatocytes, and lowers the ALT; Paeonia lactiflora has certain curative effect on habitual constipation, and it can increase the secretion of mucus of the large intestine, promote the propulsive movement of the large and small intestines, and increase the water content of large and small intestines. The main diarrhea-causing components of rhubarb are senna glycosides, aloe barbadensis and rhubarbic acid, senna glycosides are converted to anthrone rhubarbic acid by intestinal bacterial action, which acts on the middle and distal parts of the colon to increase the tension, strengthen the movement and inhibit the absorption of Na+ and water, and at the same time, the above three components of rhubarb also inhibit the absorption of glucose in the small intestine and the colon and directly enhance the electrical excitability of the intestinal smooth muscle cells, which promotes the peristalsis of the intestines, so as to increase the volume and discharge of diluted water. At the same time, the above three components of rhubarb also inhibit glucose absorption in the small intestine and colon, and directly enhance the electrical excitability of intestinal smooth muscle cells, thus promoting intestinal peristalsis, making the intestines dilute, and these effects of rhubarb on the intestinal tubes are biphasic without affecting the nutrient absorption. At the same time, it inhibits gastric acid secretion, promotes PGE production in gastric mucosa, and enhances gastric mucosal barrier effect, thus having antiulcer effect. The Decoction of Magnolia officinalis can stimulate the intestinal tube in large doses and inhibit it in small doses. Bitter amygdalin has a promoting effect on hepatocyte proliferation, and the water-soluble part of almonds can inhibit the elevation of ALT and AST, and has a lubricating laxative effect. The adjuvant drug Citrus aurantium makes the intestinal contraction rhythm increase, both excitatory gastrointestinal, so that peristalsis enhancement, but also, reduce intestinal smooth muscle tension and antispasmodic effect; Citrus aurantium in high concentrations inhibit intestinal smooth muscle, low concentrations in the transient inhibition of excitatory effect after the emergence of; in the pathologic hyperfunction, such as intestinal cramps, diarrhea, manifested in the inhibition of antispasmodic, diarrheal and analgesic; and in the hypofunction, such as gastric dilatation, gastric ptosis, gastrointestinal weakness, When the function is low, such as gastric dilatation, gastric prolapse, gastrointestinal weakness, intestinal obstruction, it shows excitatory effect, and this biphasic regulating effect on gastrointestinal dysfunction can be effectively regulated to normalize gastrointestinal motility; at the same time, hot-water extracts of Hovenia dulcis and its volatile oils can significantly reduce gastric juice secretion and pepsin activity, and have anti-ulcer effects. The adjuvant Hederacanthus vulgaris contains Hederacanthol, which has anti-hepatitis virus effect, can reduce substantial pathological damage such as degeneration and necrosis of hepatocytes, can reduce ALT, can obviously prevent hepatic fibrosis and cirrhosis formation, and can improve immune hepatic fibrosis plasma SOD activity, and reduce the content of LPO; Decoction of Hederacanthus vulgaris can inhibit excessive secretion of gastric acid, and has antiulcer effect; Volatile oil of Hederacanthus vulgaris can reflexively increase secretion of digestive glands; Decoction of Hederacanthus vulgaris has an excitatory effect on the smooth muscle of gastrointestinal tract. Honey can promote liver cell regeneration, and has an anti-ulcer effect, can significantly promote intestinal propulsion movement, reflex inhibition of gastric secretion function.

It can be seen that this formula has hepatoprotective, anti-cirrhotic, anti-ulcer effects, especially on the gastrointestinal movement of the propulsive effect, which is conducive to defecation.

4.9.2 Effects on heart, circulatory system and blood rheology

The kingpin drug Ma Ren has the effect of lowering blood pressure and prolonging coagulation time and inhibiting thrombosis. The subject medicine Paeonia lactiflora extract and Paeonia lactiflora total glycosides have protective effects on cardiac ischemia, Paeonia lactiflora can make blood vessels dilate, dilate coronary arteries, increase myocardial nutrient blood flow, increase myocardial contractility, fight against myocardial ischemia caused by pituitary posterior lobe hormone, inhibit platelet aggregation caused by ADP and arachidonic acid, reduce the platelet thrombosis of wet weight, and have antithrombotic effects. Rhubarb through the inhibition of angiotensin-converting enzyme and has a transient blood pressure lowering effect, and hypercholesterolemia has a lowering of lipid/phospholipid ratio and cholesterol effect; on internal bleeding and external bleeding have obvious hemostatic effect, so that the coagulation time is shortened, the capillary permeability is reduced, and to promote platelet generation; but rhubarb can inhibit the Ca2+ inward flow of blood platelet aggregation has an inhibitory effect; rhubarb can improve blood Rheology, rhubarb inhibits cell membrane Na + K + ATPase activity, increase plasma osmotic pressure, so that blood dilution, thereby reducing blood viscosity, improve microcirculation disorders; rhubarb also has a cardiotonic effect. Almonds contain trace element chromium can reduce cholesterol deposition and inhibit atherosclerosis, and unsaturated fatty acids contained in almonds also have hypolipidemic effect. The adjuvant drug Citrus aurantium injection can excite the heart, enhance myocardial contractility, increase cardiac output, significantly reduce coronary resistance, increase coronary blood flow, reduce myocardial oxygen consumption, improve myocardial metabolism, and at the same time, have the effect of elevated blood pressure, anti-shock. Magnolia arrow poison or Magnolia alkaloids contained in Magnolia have the effect of lowering blood pressure, while Magnolol has the effect of antiplatelet aggregation through the inhibition of thromboxane A2 (TXA2) production and inhibition of intracellular calcium transport. Honey reduces blood pressure, dilates coronary arteries and increases coronary blood flow, while increasing myocardial contractility and having cardiotonic effects. It can be seen that the formula can not only enhance myocardial function, improve coronary blood supply, but also improve blood rheology, to prevent thrombosis, and its effect on blood pressure most of the antihypertensive effect, only Hovenia is a pressure-raising effect, so as to also prevent the blood pressure drop is too much, in favor of the elderly and women in labor due to circulatory disorders due to constipation of the better.

4.9.3 Antipathogenic microorganisms

The formula has antipathogenic microorganisms except for Hesperidin. The decoction of Paeonia lactiflora has inhibitory effect on many kinds of pathogenic bacteria, with strong antimicrobial power and wide antimicrobial spectrum, which has inhibitory effect on Staphylococcus aureus, Streptococcus haemolyticus, Streptococcus grasshopperus, Streptococcus pneumoniae, Typhoid fever and Typhoid fever, dysentery bacillus, Staphylococcus, Escherichia coli, Pseudomonas aeruginosa as well as some fungi, such as Trichophyton coriaceum, Trichophyton congolese, Trichophyton rubrum, Trichophyton redskinensis, Nucoria asteroidea, and Trichophyton woolyi. Inhibitory effect, and has a direct antiviral effect. Rhubarb also has an inhibitory effect on most gram-positive and negative bacteria, in addition to some of the above bacteria, hemolytic streptococcus, gonococcus, diphtheria bacillus, bacillus subtilis, anthrax bacillus, typhoid fever bacillus are more sensitive to anaerobic fragile mimic bacillus, most of the fungi, helicobacter pylori, influenza virus, cytomegalovirus, herpes simplex virus, coxsackievirus and hepatitis B virus have inhibitory effect, at the same time At the same time, it has inhibitory effect on amoeba, *** Trichomonas and most of the fungi. Almond oil has inhibitory effect on roundworm, hookworm, typhoid and paratyphoid bacteria. Naringenin and hesperidin contained in the adjuvant drug Hovenia dulcis have inhibitory effects on most of the bacteria mentioned above, and have antiviral effects, especially on HIV. The decoction of Hederacanthus and the Hederacanthol contained therein have broad-spectrum antimicrobial effect, in addition to the inhibitory effect on most of the bacteria mentioned above, they also have obvious antimicrobial effect on gram-positive bacteria, acid-resistant bacteria, pneumococcus, staphylococcus aureus, common pathogenic skin fungi, caries bacteria, etc., and have antiviral effect, especially on hepatitis viruses. Honey has an inhibitory effect on most of the above bacteria, low concentration of antibacterial, high concentration of bactericidal, in addition to tuberculosis bacillus, Borrelia burgdorferi, etc. also has an inhibitory effect. This is especially important for constipation caused by various infectious diseases due to maternal and puerperal fever. For the elderly due to decreased immune function due to infectious diseases also has a preventive effect.

4.9.4 Effect on immune function

The ministerial herb Paeonia lactiflora has a biphasic regulating effect on various immune responses, firstly, total paeonia lactiflora glucoside plays a biphasic regulating effect on humoral immunity through the regulation of TH, TS, so as to maintain the antibody in the body at the normal level; at the same time, by prompting the release of PGE2 from macrophages, it plays a negative regulating effect on the B-cells; total paeonia lactiflora glucoside shows a function and concentration-dependent biphasic regulating effect on the T-cells function. Total paeoniflorin has a functional and concentration-dependent biphasic effect on T-cell function, which can promote the induction of specific and non-specific regulatory cells; total paeoniflorin also plays a biphasic regulatory effect on macrophages, which can induce interferon and activate the reticuloendothelial system. Rhubarb protects bone marrow cells from the destruction of immunosuppressants, and rhubarbin activates monocytes to secrete IL2 and IFNγ by coordinating phytohemagglutinin, so it has an immune-enhancing effect; rhubarb exerts a variety of immune-regulating effects on intestinal mucosal cells and brain cells. Bitter amygdalin has obvious promotion effect on the function of hepatic wither cell, lung macrophage and abdominal macrophage, meanwhile, bitter amygdalin can obviously promote the proliferation of splenic T-lymphocytes by mitogens and enhance the activity of splenic NK-cells; at the same time, it promotes the transformation of T-lymphocytes of PHA ***. The aqueous extract of Citrus aurantium and the contained hesperidin and chenpiin could inhibit compound 48/80-induced histamine release from mast cells, and hesperidin could inhibit type I allergic reactions. Huperzine can also powerfully enhance the body's immune function, can improve the body's cellular immune function, and has an anti-allergic effect. Honey has the effect of enhancing the function of humoral immunity and increasing the number of antibody-secreting cells. It can be seen that the formula can make the body's immune function reach normal through immune promotion and biphasic regulation, which is especially important for the elderly and women in labor.

4.9.5 Anti-inflammatory, antioxidant and anti-allergic effects

The alcoholic extract of Junmai Ma Zi Ren has the effects of inhibiting the increase of inflammatory capillary permeability and eliminating edema, as well as analgesic effects. Paeonia lactiflora contains paeoniflora total glycoside, peony phenol has obvious anti-inflammatory effect, on a variety of experimental non-specific inflammation and immune inflammation have obvious inhibition effect, so that the capillary permeability reduction, exudation, edema and hyperplasia improved; at the same time, paeoniflora total glycoside, danpi total glycoside of oxygen radicals and hydroxyl radicals have scavenging effect, enhance the activity of SOD and GSHPx, reduce the level of MDA, NO, TNF, inhibit the excessive IL1, PGE2, PGE2, PGE2 and PGE2, and inhibit the effect of the anti-oxidation, antioxidant and anti allergy. IL1, PGE2 over-secretion, and thus has the role of antioxidant damage. lindleyin isolated from rhubarb has anti-inflammatory activity against polyarthritis, and its anti-inflammatory activity is the same as that of aspirin. lindleyin reduces the synthesis and release of arachidonic acid metabolites leukotriene B4 and 5 hydroxyeicosatetraenoic acid, and activates monocytes to secrete TNFα and IL1, IL6, IL8, and at the same time, it can also inhibit endotoxin-induced secretion of the above factors, and it can also harmonize PHA activates monocyte secretion of IL2, INFγ; rhubarb can also scavenge oxygen free radicals, H2O2 and other reactive oxygen species, inhibit lipid peroxidation and show anti-inflammatory effects; rhubarb pigments have a better anti-inflammatory effect on early inflammation exudate, increased capillary permeability, leukocyte wander; rhubarb decoction of the acute inflammation of the oozing edema has a significant inhibition of the role of rhubarb decoction. Almond also has anti-inflammatory effect, the pepsin hydrolysis product of bitter almond has significant inhibitory effect on inflammatory edema, granulation tissue proliferation. Hesperidin and naringenin contained in Citrus aurantium have vitamin P-like activity, which can reduce capillary permeability and fragility, thus reducing inflammatory exudation, naringenin and hesperidin have a certain inhibitory effect on the non-enzymatic peroxidation and can inhibit the production of MDA, and hesperidin also has a stronger scavenging of oxygen free radicals. Hesperidin also has a strong scavenging effect on oxygen free radicals. Huperzine has an inhibitory effect on both type I and type IV metabolic reactions. These effects on maternal, especially with *** lacerations and pelvic inflammatory disease of maternal therapeutic effect, thus eliminating these causes and make constipation relief.

4.10 Song

Ma Zi Ren Pills for Spleen, Rhubarb, Peony, Apricot and Park Hovenia;[4]

4.11 Source

The Treatise on Typhoid Fever (伤寒论), "Discussion of Yangming Disease" (伤寒论), "Pulse and Evidence of Yangming Disease" (伤寒论), "The Treatise on Typhoid Fever" (伤寒论), "Discussing Yangming Disease" (阳明疾病), "The Treatise on Yangming Disease". 9 grams. 10 pills per box.

5.4 Main Ingredients of Ma Zi Ren Pills

Fire Ma Zi Ren, White Peony, Bitter Almond, Citrus aurantium dulcis, Magnolia officinalis, Rheum palmatum, Rheum palmatum.

5.5 The pharmacological effect of Ma Zi Ren Pills

Flaxseed kernel, almonds contain fatty oils active substances, can strengthen the peristalsis of the intestinal tube, laxative effect is obvious. Rhubarb contains anthraquinone compounds, enhance peristalsis and diarrhea, dysentery bacillus, Escherichia coli, Pseudomonas aeruginosa, Streptococcus, Diplococcus pneumoniae, and skin fungi, etc., have antibacterial effect. White peony mainly contains paeoniflorin, with antispasmodic, sedative, analgesic and elevate peripheral white blood cells, improve the conversion rate of lymphocytes and other effects. The thick Park on the intestinal smooth muscle has an excitatory effect, also has antibacterial effect on Staphylococcus aureus, S. pneumoniae and dysentery. The inhibitory effect on Staphylococcus aureus, S. pneumoniae and S. dysenteriae is obvious. Citrus aurantium can make the gastrointestinal motility contraction rhythm enhancement powerful.

5.6 Functions of Hemp Seed Pills

Moistening the intestines and draining heat, and promoting the flow of Qi and laxatives. It is used for treating dryness and heat in the intestines and stomach, and constipation in the spleen. Symptoms include dry stools, frequent urination, red face and body heat, or both abdominal distension, abdominal pain, dry mouth and halitosis, red tongue with yellow or yellow dryness, and slippery pulse. It is suitable for the treatment of the weak and the elderly intestinal dry constipation, habitual constipation, *** constipation after surgery, roundworm intestinal obstruction.

5.7 Usage and dosage of Hemp Seed Pills

1 to 2 times daily, 9 grams each time, with warm water.

5.8 Precautions

Use with caution in patients with empirical evidence.

5.9 Expert comments

1. Fire Ma Ren, almonds contain fatty oil active substances, can strengthen the peristaltic effect of the intestinal tube, laxative effect is obvious. Rhubarb contains anthraquinone compounds, enhance peristalsis and diarrhea, dysentery bacillus, Escherichia coli, Pseudomonas aeruginosa, Streptococcus, Diplococcus pneumoniae, and skin fungi, etc., have antibacterial effect. White peony mainly contains paeoniflorin, with antispasmodic, sedative, analgesic and elevate peripheral white blood cells, improve the conversion rate of lymphocytes and other effects. The thick Park on the intestinal smooth muscle has an excitatory effect, also has antibacterial effect on Staphylococcus aureus, S. pneumoniae and dysentery. The inhibitory effect on Staphylococcus aureus, S. pneumoniae and S. dysenteriae is obvious. Citrus aurantium can make the gastrointestinal motility contraction rhythm enhancement powerful. Therefore, it is mainly used for the treatment of constipation with intestinal dryness and stagnation. The elderly and postpartum intestinal dryness and constipation and habitual constipation and other diseases.

2. Clinical application: used in the treatment of the weak and the elderly intestinal constipation, habitual constipation, *** post-surgical constipation, roundworm intestinal obstruction.

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