Table of Contents 1 Pinyin 2 English Reference 3 General 4 Latin Name 5 English Name 6 Alias of Ligusticum 7 Source 8 Place of Origin 9 Taste and Meridian 10 Efficacy and Indications of Ligusticum 11 Chemical Composition of Ligusticum 12 Pharmacological Actions of Ligusticum 13 Pharmacopoeial Standard of Ligusticum 13.1 Name 13.2 Source 13.3 Character 13.3.1 Ligustrum 13.3.2 Liao Ligustrum 13.4 Identification 13.5 Examination 13.5. 1 Moisture 13.5.2 Total Ash 13.5.3 Acid-insoluble Ash 13.6 Leachate 13.7 Content Determination 13.7.1 Chromatographic Conditions and System Suitability Tests 13.7.2 Preparation of Control Solution 13.7.3 Preparation of Supplementary Solution 13.7.4 Assay 13.8 Ligusticum Drinking Tablets 13.8.1 Concoction 13.8.1.1 Ligustrum Ligusticum Tablets 13.8.1.2 Liao Ligustrum lucidum tablets 13.8.2 Examination 13.8.2.1 Total ash 13.8.2.2 Acid-insoluble ash 13.8.3 Identification, examination 13.8.4 Leachate, determination of content 13.8.5 Taste and attribution 13.8.6 Functions and Indications 13.8.7 Methods of use and dosage 13.8.8 Storage 13.9 Provenance 14 References Attachments: 1 Formulas using Chinese medicine ligustrum lucidum 2 Proprietary Chinese medicines using ligustrum lucidum [Landau Chinese-English Dictionary]

rhizoma et radix ligustici [Landau Chinese-English Dictionary]

rhizoma et radix ligustici sinensis [Landau Chinese-English Dictionary]

Chinese lovage [Xiangya Medical Professional Dictionary]

ligustici sinensis [Longman Chinese-English Dictionary]

ligustici sinensis [Longman Chinese-English Dictionary]

ligustici sinensis [Longman Chinese-English Dictionary] <

ligustici sinensis,radix [Xiangya Medical Dictionary]

ligustici,rhizoma [Xiangya Medical Dictionary]

Chinese ligusticum rhizome [Xiangya Medical Dictionary]

ligusticum [Xiangya Medical Dictionary]

ligusticum [Xiangya Medical Dictionary]

ligusticum [Xiangya Medical Dictionary]

Rhizoma Ligustici(la) [Nomenclature Review Committee of Chinese Medicine. Chinese Medicine Nomenclature (2004)]

Chinese lovage [中中醫学名词审定委员会. Chinese Medicine Nouns (2004)]

3 Overview

Ligusticum is the name of the Chinese medicine, out of the "Shennong Ben Cao Jing" [1]. It is the dried rhizome and root of Ligusticum sinense Oliv. or Ligusticum jeholense Nakai et Kitag. of Umbelliferae[2].

The Pharmacopoeia of the People's Republic of China (2010 edition) contains pharmacopoeial standards for this herb.

4 Latin name

Rhizoma Ligustici (拉) ("Nomenclature of Chinese Medicine (2004)")

5 English name

Chinese lovage ("Nomenclature of Chinese Medicine (2004)")

6 Alias of Ligustici

Wild celery, mountain parsley [1].

7 Source

Ligusticum is the dried rhizome and root of Ligusticum sinense Oliv. or Ligusticum jeholense Nakai et Kitag. of the family Umbelliferae[2].

Ligusticum is the rhizome and root of Ligusticum *** ense Oliv. or Liao Ligusticum L. jeholense Nakai et Kitag. of the Umbelliferae family [1].

8 Place of origin

Ligusticum is mainly produced in Hubei, Hunan, Sichuan; Liao Ligusticum is mainly produced in Hebei, Liaoning [1].

9 Sexual flavor and attribution

Ligusticum officinale is pungent in flavor and warm in nature; it enters the bladder meridian [1].

10 Ligustrum efficacy and treatment

Ligustrum has the efficacy of expelling wind, winning dampness, and relieving pain[1]:

Ligustrum treatment of wind-cold cold, summit pain, migraine, wind-dampness, bone pain, cold-dampness, abdominal pain, and diarrhea: decoction, 3 to 9g[1].

Ligustrum cure scabies acne, rosacea: decoction wash [1].

Ligustrum is commonly used in ophthalmology to dispel wind and cold, has the effect of dispelling wind and dampness, dispersing cold and relieving pain, used for wind-cold-induced pain in the head and eyes, the top of the top of the severe pain, pain even teeth and cheeks and migraines, etc. The product has the effect of dispelling wind and dampness, dispersing cold and relieving pain. This product is pungent and warm, good to reach the top of the roof, pain relief, often with chuanxiong, dahuric dahurica, such as Shenjusan ("Hejiaobu Fang").

11 Chemical constituents of Ligusticum

Ligusticum contains volatile oil, which mainly contains 3-butylphthalide, Chuanxiong lactone (Cnidilide), eugenol methyl ether, etc. [1].

Liao Ligustrum root contains volatile oil [1].

12 Pharmacological effects of Ligustrum officinale

Ligustrum officinale decoction has inhibitory effects on certain pathogenic skin fungi in vitro [1].

The neutral oil of Ligustrum has sedative, analgesic and antipyretic effects on experimental animals, as well as significant anti-inflammatory effects [1].

13 Pharmacopoeia standard of Ligusticum 13.1 Name

Ligusticum

Gaoben

LIGUSTICI RHIZOMA ET RADIX

13.2 Source

This product is the Umbelliferous plant Ligusticum sinense Oliv. or Liao Ligusticum Ligusticum Nakai? Ligusticum sinense Oliv. or Ligusticum liao Ligusticum jeholense Nakai? et? Kitag. Autumn stems and leaves withered or the next spring when the seedlings are dug, remove the sediment, sun-dried or dried.

13.3 Traits 13.3.1 Ligustrum

The rhizome is irregular nodular cylindrical, slightly twisted, with branches, 3-10 cm long, 1-2 cm in diameter. the surface is brown or dark brown, rough, with longitudinal wrinkles, the upper side of the residue of several depressed rounded stems, the lower side of the majority of dotted protruding root scars and root stumps. Light, hard, easy to break, yellow or yellow-white cross-section, fibrous. Gas strong aroma, taste pungent, bitter, slightly numbing.

13.3.2 Liao Ligustrum

Smaller, the rhizome is in the form of irregular lumps or columns, 1-3cm long, 0.6-2cm in diameter, with most of the slender curved roots.

13.4 Identification

Take 1g of powder, add 10ml of ether, cold soak for 1 hour, ultrasonic treatment for 20 minutes, filtration, filtrate concentrated to 1ml, as a test solution. Also take 1g of ligustrum control herb, the same method into the control herb solution. According to the thin layer chromatography (Appendix VIB) test, absorb the above two solutions of 1μl, respectively, point in the same silica gel G thin layer plate, with petroleum ether (60 ~ 90 ℃) - acetone (95:5) as the unfolding agent, unfolding, spreading distance of 10cm, remove, dry, and placed in the ultraviolet lamp (365nm) under the examination. In the chromatogram of the test article, in the corresponding position with the chromatogram of the control herb, the main fluorescent spots of the same color.

13.5 Check 13.5.1 Moisture

Not more than 10.0% (Appendix IXH second method).

13.5.2 Total ash

Not more than 15.0% (Appendix IXK).

13.5.3 Acid-insoluble ash

Not more than 10.0% (Appendix IXK).

13.6 Leachate

Determined according to the alcohol soluble leachate method (Appendix XA) under the hot leaching method, with ethanol as a solvent, not less than 13.0%.

13.7 Content determination

Determined by high performance liquid chromatography (Appendix VI D).

13.7.1 Chromatographic conditions and system suitability test

Octadecylsilane-bonded silica gel as filler; methanol-water (40:60) (pH adjusted to 3.5 with phosphoric acid) as the mobile phase; detection wavelength of 320 nm. the theoretical number of plates according to the ferulic acid peaks should not be less than 2,500.

13.7.2 Preparation of control solution

Precision weighing of the control solution as a solvent. Preparation

Precision weighing of ferulic acid control appropriate amount, add methanol to make a solution containing 15μl per 1ml, that is obtained.

13.7.3 Preparation of test solution

Take about 0.1g of crude powder of this product, weigh it precisely, put it in 10ml centrifugal tube with stopper, add 5ml of methanol precisely, weigh it, immerse it in cold water overnight, ultrasonic treatment (power 250W, frequency 40kHz) for 20 minutes, weigh it again, make up the lost weight with methanol, shake, centrifugation, aspirate the supernatant, that is, get it.

13.7.4 Determination

Precisely aspirate 10μl each of the control solution and test solution, inject into the liquid chromatograph, determination, that is obtained.

This product is calculated according to the dry product, containing ferulic acid (C10H10O4) shall not be less than 0.050%.

13.8 Ligustrum tablets 13.8.1 Concoction

Remove impurities, wash, moisten, cut thick slices, sun-dried.

13.8.1.1 Ligustrum lucidum slices

The product is irregular thick slices. The outer skin is brown to black brown, rough. The cut surface is yellowish white to light yellowish brown, with fissures or holes, fibrous. Gas strong aroma, taste pungent, bitter, slightly numbing.

13.8.1.2 Liao Ligustrum Slices

Root scars and stubs protruding in the form of burrs can be seen on the outer epidermis, or there are old stem stumps in the form of withered cavities. The wood of the cut surface has radial texture and fissures.

13.8.2 Inspection 13.8.2.1 Total ash

Same as the herbs, not more than 10.0%.

13.8.2.2 Acid insoluble ash

The same herbs, not more than 5.0%.

13.8.3 Identification, inspection

(moisture) with the herbs.

13.8.4 Leachate, content determination

Same as the herbs.

13.8.5 Flavor and Meridian

Pungent, warm. Attributed to the bladder meridian.

13.8.6 Functions and Indications

Dispelling wind, dispersing cold, removing dampness and relieving pain. It is used in treating wind-cold and flu, pain in the top of the head, and rheumatism and paralysis.

13.8.7 Method of use and dosage

3~10g.

13.8.8 Storage

In a cool and dry place, moisture-proof, moth-proof.

13.9 Provenance