Acne is a chronic inflammatory skin disease involving sebaceous glands in hair follicles, and its pathogenesis has not been fully clarified. Heredity, androgen-induced sebum secretion, keratosis of sebaceous ducts in hair follicles, propagation of Propionibacterium acne, immune inflammatory reaction and other factors may all be related to it. The treatment principle of acne is mainly to remove fat, dissolve keratin, sterilize, diminish inflammation and adjust hormone level. General treatment includes cleaning skin moderately, avoiding squeezing and scratching, reducing the intake of high-sugar food and milk, developing good defecation habits and avoiding staying up late. Topical drugs mainly include tretinoin, benzoyl peroxide, antibiotics such as fusidic acid, erythromycin, lincomycin, clindamycin and chloramphenicol. Patients with severe symptoms can take isotretinoin orally under the guidance of a doctor or take antibiotics such as doxycycline and minocycline. In addition, methods such as phototherapy and chemical peeling therapy can also be used to eliminate acne on the face.