This is usually related to the non-liquefaction of semen. The non-liquefaction of semen is due to the insufficiency or destruction of proteolytic enzyme secretion, which leads to the imbalance of enzyme system, so that some patients' semen does not liquefy after being placed 1 hour, or the semen is not completely liquefied and the viscosity is too high. In this case, sperm cannot migrate, which will naturally lead to infertility. This disease is related to the disorder of secretion of proteolytic enzyme, fibrinolytic enzyme and semen liquefaction factor after accessory gonad infection, which makes semen unable to liquefy.