The disease can be divided into three types according to the course of the most acute, acute and chronic. The most acute type, does not show any abnormality, often in the process of driving, running, jumping suddenly died. Acute type, the sick cattle spirit depressed, visible mucous membrane staining or yellow staining, appetite greatly reduced, intestinal sound weak, diarrhea, feces mixed with blood and mucus, body temperature does not rise. The back and waist are hard, the gait is strong and constrained, the hindquarters are shaking, and in the late stage, they often lie down on the ground, and the buttocks are swollen and hard and solid when touched. Respiration is accelerated, pulse rate increases, and calves reach more than 120 times/minute. Chronic type, slow movement, unsteady gait, like lying down. The spirit is depressed, appetite decreases, and there is heterophilia. Coat rough, lack of luster, yellow and white mucous membranes, diarrhea and polyuria, pulse rate increases, respiration accelerated. _