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What is the principle of anti-hangover drugs?
The key to solving drunkenness lies in how to make the vital organs of human body, central nervous system and blood contact with the toxic substance "acetaldehyde" produced after alcohol (ethanol) enters human body as little as possible, so as to reduce the oxidation ability of acetaldehyde to cells.

the substance that plays a major role in resisting the spread of acetaldehyde in human body is AldDGH2 produced by human body itself, which is a dehydrogenase that can actively resist acetaldehyde and decompose it into nontoxic acetic acid, carbon dioxide and water before it reaches the liver. The active components in RU21 can accelerate the decomposition of acetaldehyde and improve the metabolic ability of alcohol by stimulating human glands to produce a large number of dehydrogenases, thus essentially solving the problem of drunkenness.

When drinking, alcohol enters the blood through the stomach and intestines, which is called "absorption". Alcohol is metabolized by enzymes. This enzyme (alcohol dehydrogenase) is a chemical in the body, which can decompose other chemicals. It converts toxic substances produced by alcohol metabolism into nontoxic acetic acid. Acetic acid can be quickly converted into energy by human body and finally decomposed into water and carbon dioxide. However, no matter how much alcohol is consumed, the human body can only metabolize a certain amount of toxic substances in a certain period of time. Therefore, alcohol metabolism often causes too many toxic substances to enter the blood, which in turn leads to serious damage to important organs and functions of the human body.

ru21 balances alcohol metabolism by slowing down the process of ethanol oxidation to toxic substances, and accelerates the transformation of toxic substances into acetic acid, water and carbon dioxide, thus reducing toxic substances.

the dextrose (glucose) contained in p>ru21 can successfully complete the first step, which is to slow down the ethanol oxidation process. In the liver cell fluid, dextrose reacts with NAD pool cell fluid used for ethanol decomposition, which is rapidly oxidized, resulting in insufficient NAD cell fluid needed for the reaction.

in the second step, the matrix (succinic acid and fumaric acid) accelerates the decomposition of toxic substances into acetic acid, carbon dioxide and water. The matrix contained in ru21 can activate the second part of tricarboxylic acid circulation, which can activate the mitochondria oxidation process and play a stronger anti-toxic role. Metabolite accumulation and prevention of NADH oxidation in the respiratory chain of cells can lead to oxygen deficiency, and succinate matrix independent of NADH dehydrogenase can prevent toxins from causing oxygen deficiency.

the addition of l-glutamate to p>ru21 can accelerate the transport of mitochondrial-malic-aspartate, which plays a very important role in the production of toxins. L- glutamate can also prevent the inhibition of succinate dehydrogenase by oxalis and acetic acid, and accelerate the oxidation process of succinate. In addition, in Krebs cycle (tricarboxylic acid cycle), L- glutamate is rapidly oxidized and converted into A- ketoglutarate. Finally, the concentration of L- glutamate affects glutamate and GAMC synapses in the brain, coordinating and inhibiting the injury process caused by alcoholism.

vitamin c ascorbate contained in p>ru21 is used to maintain the antioxidant system of the central nervous system, liver and hormone-active tissues, and to maintain the adrenal cortex that produces anti-stress hormones.