2 English reference Daphnium Myrrha [Landau Chinese-English Dictionary]
Viville Linderae. Landau Chinese-English Dictionary
Landau Chinese-English dictionary
Lindera root [Xiangya medical dictionary]
Xiangya Medical Dictionary
Committee on terminology of traditional Chinese medicine. Terminology of Traditional Chinese Medicine (2004)]
Committee on terminology of traditional Chinese medicine. Terminology of Traditional Chinese Medicine (2004)]
3 Overview of Linderae
Lindera root is the name of traditional Chinese medicine, which comes from Compendium of Materia Medica [1]. It is the dried root of Lindera root. [2].
Pharmacopoeia of People's Republic of China (PRC) (20 10 edition) records the pharmacopoeia standard of this Chinese medicine.
4 Latin scientific name Lindera root (Chinese medicine terminology (2004)).
5 English name bined Lindera (Chinese Medicine Terminology (2004))
6 alias of Lindera root [1].
Cinnamomum camphora var. Cinnamomum camphora var. humicola. Strawberries
7. Lindera root tuber. [1]. Location: Zhejiang, Hunan, Anhui, Guangdong, Guangxi [1].
8 Plant morphology Evergreen shrubs or small trees, up to 4m. The leaves are leathery, ovoid or ovoid, the tail tip is tapered or short, the upper part is shiny, the lower part is densely gray and white, and the veins are three. Dioecious; Umbellies axillary, peduncle short or absent; Tepals 6, yellow-green; Male flowers have stamens 9; The female flower has staminodes and the ovary is superior. Drupe is spherical and black. Flowering in March-April and fruiting in September-65438+1October.
Born in sunny slopes, foothills and wild bushes. Location: Anhui, Zhejiang, Hunan, Guangdong and Guangxi.
9. You can dig, remove fine roots, slice or directly dry them all year round.
10 characteristics: the root tuber is spindle-shaped, slightly curved, and some parts contract into beads in the middle. The surface is yellowish brown or yellow, with longitudinal wrinkles and sparse fine root marks. Hard, yellow-white or yellow-brown, radial, ring-shaped, with dark center. Delicious, slightly bitter and spicy, with a cool feeling.
1 1 Xinwen [1]. Into spleen, lung, kidney and bladder meridian [1].
The main functions of 12 are to relieve pain, dispel cold and warm kidney [1]. Indications: Abdominal distension and abdominal pain, nausea and vomiting, dyspepsia, syncope, headache, colic, dysmenorrhea, frequent urination and enuresis [1].
13 usage and dosage of Lindera root decoction: 3 ~ 9g [1].
14 chemical constituents This product contains volatile oil and many sesquiterpenes: Lindera lactone, linalool lactone and Lindera ene; Linderenol), Lindenene, Lindestrene, etc. It also contains azone, linalool, linderamic acid and sitosterol [1].
15 pharmacological action this product contains borneol, which has sweating, excitement, spasmolysis and anthelmintic effects; Chamaznlene contained in it has anti-inflammatory and antifungal effects [1].
16 Lindera root 16. 1 is called Lindera root.
Wuyao
root of three-nerved spicebush
16.2 Source This product is the dried root tuber of Lindera root. You can dig, remove fine roots, wash, slice when fresh, dry in the sun or directly dry in the sun all year round.
Features 16.3 Most products are spindle-shaped, slightly curved, and some of them are beaded in the middle, with a length of 6 ~ 15 cm and a diameter of 1 ~ 3 cm. The surface is yellowish brown or yellowish brown, with longitudinal wrinkles and sparse fine root marks. It's hard. Slices are 0.2~2mm thick, with yellow-white or yellow-brown section, radial rays, visible noon ring and dark central color. Delicious, slightly bitter and spicy, with a cool feeling.
Old, spindle-shaped straight roots are not used in medicine.
16.4 Identification (1) This product is yellow and white. There are many starch granules, and a single granule is spherical, oblong or oval, with a diameter of 4 ~ 39 μ n, and the umbilical point is forked, herringbone or cracked. Composite particles are composed of 2 ~ 4 parts. Wood fibers are light yellow, mostly in bundles, with a diameter of 20 ~ 30μ m and a wall thickness of about 5 μ m. There are simple pits and starch granules in the cell cavity. The bast fibers are nearly colorless, long, spindle-shaped, and scattered, with a diameter of 15 ~ 17 microns, extremely thick walls and inconspicuous pores and grooves. The diameter of the duct with edge holes is about 68μm, and the edge holes are closely arranged. The cell wall of wood ray is slightly thickened and the pits are dense. Oil cells are rectangular and contain brown secretions.
(2) Take 65438+0g of this product powder, add 30 ml of petroleum ether (30 ~ 60℃), stand for 30min, perform ultrasonic treatment (keep the water temperature below 30℃) for 65438+00min, filter, evaporate the filtrate, and add 65438±0ml of ethyl acetate to the residue to dissolve it, which will be used as the test solution. In addition, 65438 0 g of Lindera root was taken as the control medicinal material, and the control medicinal material solution was prepared by the same method. Dissolve linderaine reference substance in ethyl acetate to prepare a solution containing 0.75mg reference substance per 1ml. According to the thin-layer chromatography test (Appendix Ⅵ d), take 4μl of test solution, 4μl of control medicinal solution and 3μl of control medicinal solution, respectively, and spot them on the same silica gel H thin-layer plate, with toluene-ethyl acetate (15: 1) as the developing agent, unfold, take out, dry and spray with1. In the chromatogram of the test sample, spots with the same color appear at the positions corresponding to the chromatograms of the reference medicinal materials and the reference substance.
The water content of 16.51shall not exceed 1 1.0% (appendix ⅸ h, second method).
16.5.2 the total ash content shall not exceed 4.0% (appendix ⅸ k).
16.5.3 the acid-insoluble ash content shall not exceed 2.0% (appendix ⅸ k).
16.6 extract is determined by the hot soaking method under the alcohol-soluble extract determination method (appendix X A), with 70% ethanol as the solvent, which shall not be less than 12.0%.
16.7 content determination 16.7. 1 lindane was determined by high performance liquid chromatography (appendix 6 d).
16.7. 1. 1 chromatographic conditions and system applicability test with octadecylsilane bonded silica gel as filler; Acetonitrile-water (56: 44) was used as the mobile phase. The detection wavelength is 235 nm. The theoretical plate number should be not less than 2000 calculated by the peak of Lindane.
16.7. 1.2 preparation of control solution take 10mg of lindane control substance, accurately weigh it, put it in a 100ml volumetric flask, dissolve it in methanol and dilute it to scale, shake it evenly, accurately measure 10ml, and put it in a 25ml volumetric flask.
16.7.10.3 Preparation of test solution Take about 1g of the crude powder of this product, weigh it accurately, put it in Soxhlet extractor, add 50 ml of ether, extract for 4 hours, volatilize the extract, dissolve the residue in methanol for several times, transfer it to a 50 ml volumetric flask, add methanol to the scale, shake well, filter, and take it.
16.7. 1.4 determination method accurately absorbs 10μl control solution and test solution respectively, injects them into a liquid chromatograph, and measures them.
In terms of dry products, the content of Lindane (C 15H 1604) in this product shall not be less than 0.030%.
16.7.2 determination of norisoproterenol by high performance liquid chromatography (appendix ⅵ d).
16.7.2. 1 chromatographic conditions and system applicability test with octadecylsilane bonded silica gel as filler; Acetonitrile was used as mobile phase A, and a solution containing 0.5% formic acid and 0. 1% triethylamine was used as mobile phase B, and gradient elution was carried out according to the regulations in the following table; The detection wavelength is 280 nm. According to the peak setting calculation of Novipol, the theoretical plate number should be not less than 5000.
Time (minutes): mobile phase A(%) mobile phase B (%) 0 ~13/kloc-0 → 22 90 → 7813 ~ 22 22 7816.7.2.2 Preparation of reference solution.
16.7.2.3 preparation of test solution take about 0.5g of this product powder (pass through No.3 sieve), weigh it accurately, put it in a round-bottomed flask, add 25ml of mixed solution of methanol-hydrochloric acid solution (0.5 → 100) (2: 1), and plug it accurately.
16.7.2.4 determination method accurately suck 5μl of control solution and 5 μ l of test solution respectively, and inject them into liquid chromatograph for determination.
This product contains no less than 0.40% of norisopropylidene (C 18H 19N04), calculated as a dry product.
16.8 Radix Linderae decoction pieces 16.8. 1 If not sliced, remove the fine roots, size them, soak them, slice them and dry them.
This product is round and flaky. The skin is yellow-brown or yellow-brown. The section is yellow-white or yellow-brown, with radial rays and visible annual rings. Crispy. Delicious, slightly bitter and spicy, with a cool feeling.
16.8.2 Identification, inspection, extract and content determination are the same as those of the medicinal materials.
16.8.3 Sexual taste and pungent and warm meridian tropism. Enter lung, spleen, kidney and bladder meridian.
16.8.4 Functions and indications: activating qi and relieving pain, warming kidney and dispelling cold. It can be used for cold coagulation, qi stagnation, chest pain, dyspnea due to qi, bladder deficiency and cold, enuresis and frequent urination, hernia pain, and abdominal pain during menstruation.
16.8.5 Usage and dosage 6 ~ 10g.
16.8.6 Store in a cool and dry place to prevent insects from eating.
16.9 Source