Thyroid hormone is a hormone secreted by the thyroid gland, which can effectively regulate the body's sugar, fat, protein metabolism, and promote cellular oxidation, but also plays an important role in the development of the central nervous system, congenital hypothyroidism can lead to a lack of secretion of thyroid hormone, which is commonly referred to as "cretinism," which affects the pediatrician. This will affect the growth and intellectual development of children. In adults, insufficient secretion of thyroid hormone or insufficient biological effect caused by hypothyroidism is called hypothyroidism, which can cause damage to various systems of the body, such as elevated blood lipids, abnormal sexual function, atherosclerosis, coronary heart disease, etc. Therefore, for adults with hypothyroidism and cretinism, it is very important that they have a good understanding of their condition. Therefore, for adults with hypothyroidism and cretinism, it is necessary to supplement thyroid hormone. Eugenol, commonly known as levothyroxine sodium tablets, belongs to synthetic thyroid hormone, which is similar to thyroid hormone synthesized by human body, and it can promote the synthesis of proteins and enzymes, and enhance energy metabolism. It is the first choice for the treatment of cretinism and hypothyroidism.

Oral eugenol is mainly absorbed in the small intestine, the highest absorption rate when taken on an empty stomach, up to 80%, and the maximum absorption effect can be obtained within 3 hours after taking the drug, and when taken with food, the absorption rate of eugenol will be greatly reduced, usually down to about 60%, so pharmacist Sun suggests that eugenol should be chosen to be taken on an empty stomach, so that it can be a more stable thyrotropin concentration, which is beneficial to the drug to give full play to its therapeutic effect. In order to improve medication compliance, it is best to take it early in the morning. Some studies have confirmed that Eugenol can be taken 30-60 minutes before breakfast to get the best absorption effect, in addition, taking it before going to bed can also get a higher absorption rate, which is also a good choice, and the patient can choose the time to take the medication according to their own situation.

Iron, magnesium, calcium and other metal ions in food, as well as protein, fiber and other components will have a significant impact on the absorption of eugenol, a study has confirmed that wheat bran, brown rice, oats, buckwheat, celery and other fiber-rich foods, especially wheat bran can produce a strong adsorption effect on eugenol, significantly affecting its absorption, in addition, soy products, strong coffee, In addition, soy products, strong coffee, grapefruit (grapefruit) can also significantly affect the absorption of eugenol, so if you choose to take eugenol before breakfast, then you should avoid eating the above foods at breakfast, and if you choose to take eugenol before bed, then you should avoid eating the above foods at dinner.

In addition, cruciferous vegetables such as purple kale, bok choy, cabbage, Chinese cabbage, mustard greens contain thiocyanate, which reduces the iodine uptake ability of the thyroid gland, and also has a certain effect on the efficacy of eugenol, so during the period of taking eugenol, a large amount of cruciferous vegetables should be avoided. Pharmacist Sun gives a suggestion to you to cook these cruciferous vegetables, which contain thiocyanate salt content will be significantly reduced, it is best not to eat these vegetables raw.

In addition to food, some drugs can also affect the absorption of eugenol, such as aluminum hydroxide, aluminum thioglycollate, magnesium aluminum carbonate and other drugs to treat gastric diseases, as well as iron, calcium, etc., which contain aluminum ions, iron ions and calcium ions and other high-valent cations, and eugenol in the intestinal tract to form an insoluble complex, which impedes its absorption, and also such as ranitidine, famotidine, omeprazole, lansoprazole, and other acid inhibitors can elevate gastric absorption. Acid suppressants such as ranitidine, famotidine, omeprazole, lansoprazole, etc. can elevate the pH value in the stomach, which may accelerate the release of eugenol in the gastrointestinal tract, thus hindering its absorption, so eugenol should be taken at least 4 hours apart from the above drugs.

In conclusion, Eugenol is an indispensable physiological hormone in the human body, and is the drug of choice for the treatment of cretinism and hypothyroidism. It is best absorbed on an empty stomach, and the absorption of Eugenol can be significantly affected by foods rich in dietary fiber, protein, iron, calcium, and strong coffee, and also by cruciferous vegetables that can reduce the iodine uptake of the thyroid, which can affect the efficacy of Eugenol. Therefore, during the period of taking Eucerin, you should avoid consuming a large amount of the above mentioned food and drink, and cruciferous vegetables are best consumed after being cooked, and some medications can also interact with Eucerin and affect the absorption of Eucerin, so you should avoid using them in combination.