Nanjing Long-distance East Railway Station operates nearly 140 lines, mainly undertaking long-distance passenger transport in southern Jiangsu, Yangzhou and Taizhou, as well as seven provinces and regions including Zhejiang, Fujian, Guangdong, Hebei, Jiangxi, Hunan and southern Anhui. It covers nearly 100 cities and counties in Jiangsu, Zhejiang, Fujian, Jiangxi, Henan, Hebei, Anhui, Guangdong and other provinces. Shuttle buses in the camp include Hyundai, Daewoo, Volvo, Caspar, Jinlong and Yutong. There are more than 500 flights every day, with an average of10.5 million passengers per day, and the passenger export volume during peak hours can reach 60,000 passengers.

The station adopts advanced computer fare collection system and voice broadcast system. On the basis of realizing the online ticket sales in the whole city, it has successfully realized the online ticket sales with the first-class bus terminal and some second-class bus terminals under the jurisdiction of the whole province. The waiting hall of East Station is spacious and bright, with dining and shopping places. Equipped with large cold and heat exchange air conditioning. The luxury waiting room is equipped with central air conditioning and rear projection TV to meet the waiting needs of luxury car passengers.

In order to ensure the safety of passengers, the station also has a dangerous goods detector, and an electronic monitoring system covering the whole station is installed to implement 24-hour monitoring to create a safe and comfortable riding environment.