No matter whether there is a good route or not, it's best not to be seen, because it's a mess.
Who can see the box under your desk? It is better not to do it, and the cost of buying such a chassis is higher. It is best to use it to add more memory.
I forgot to mention that the transparent side plates of high-grade chassis are all made of special materials and have certain anti-radiation and anti-electromagnetic interference capabilities. If it's a cheap chassis, it's better than nothing.