With the changes in the consumption demand of FMCG products by Chinese residents, FMCG enterprises are facing challenges in terms of more segmented market and more rapid response. At the same time, the process of economic globalization has accelerated, foreign enterprises have landed in China's fast moving consumer goods market, the national enterprises have a huge impact. The traditional management mode has been difficult to adapt to the competitive requirements of the information age, supply chain management as an important part of modern enterprise management, with advanced concepts and flexible response mechanism, has become the preferred program for the reform of China's FMCG industry. The implementation of supply chain management has become an inevitable means for China's FMCG industry to meet the domestic market demand and compete with the international companies. This paper first analyzes the production and sales characteristics of China's FMCG, as well as the market development trend according to the changes in consumer consumption structure and habits, and reconstructs the agile supply chain management system of FMCG after the transformation of the distribution channel by combining with the agile supply chain construction method. Then it puts forward the demand of management information system under the new mode, analyzes and discusses the key computer and communication technologies, such as mobile commerce, RFID technology, system integration technology based on webSerVice, etc., and designs the relevant system realization scheme. Finally, a supply chain management system platform centered on FMCG manufacturers is constructed. The research results of this paper provide a new management mode and application solution for the supply chain management of FMCG industry, and construct a highly efficient integrated operation system. The program in the implementation of the existing system and equipment as the basis, with a small investment, fast, easy to apply and so on, to achieve the information resources **** enjoy and business interoperability function, the fast moving consumer goods industry supply chain transformation and management has a wide range of reference and application value.