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nephrotic syndrome
Diagnosis includes three aspects: 1. Nephrotic syndrome or not. 2. Diagnosis of etiology: Only by excluding secondary etiology and hereditary diseases can primary nephrotic syndrome be diagnosed. It is best to do a renal biopsy and make a pathological diagnosis. 3. Determine if there are any complications.

Diseases requiring differential diagnosis mainly include the following diseases:

Pay attention to rest, prevent infection and avoid going to public places. People with stable condition should take appropriate activities to prevent the formation of venous thrombosis.

Give a normal amount of high-quality protein (animal protein rich in essential amino acids) 0.8-1.0g/(kg d).

Ensure sufficient heat, not less than126-147 kj/kg (30-35 kcal/kg) every day.

Do not advocate a high-protein diet.

Low-salt diet (< 3g/d) should be adopted when edema occurs. In order to reduce hyperlipidemia, we should eat less diets rich in saturated fatty acids and more diets rich in unsaturated fatty acids.

1. diuresis and detumescence

2. Reduce proteinuria

1. glucocorticoid

2. Cytotoxic drugs

3. Calmodulin inhibitors

4. Mycophenolate mofetil

The main factors affecting the prognosis of nephrotic syndrome are: 1. Pathological types: minimal change nephropathy and mild mesangial proliferative glomerulonephritis have good prognosis, while mesangial capillary nephritis, FSGS and severe mesangial proliferative glomerulonephritis have poor prognosis. Membranous nephropathy also has a certain remission rate in the early stage, but it is difficult to relieve in the later stage. 2. Clinical manifestations: Patients with massive proteinuria, severe hypertension and impaired renal function have poor prognosis. 3. Effect of hormone therapy: The prognosis of hormone sensitive person is relatively good, and the prognosis of hormone resistant patients is poor. 4. Complications: Recurrent nephrotic syndrome caused by repeated infection has a poor prognosis.