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What are the symptoms of Gardner syndrome? How is Gardner syndrome treated? What are the precautions?

Manifestations of Gardner syndrome: multiple visceral polyps, mostly in the colorectum, but also in the stomach, duodenum, and small intestine. Various soft tissue tumors: such as fibromas, lipomas, neurofibromas, epidermoid cysts, sebaceous cysts, and thyroid cancer. Desmoid tumors are rare, slow-growing tumors. Desmoid tumors are considered one of the most difficult to treat symptoms of Gardner syndrome and are the leading cause of death after colon resection. Multiple osteoma: Osteoma is a benign, slow-growing bone disease that commonly occurs in people with Gardner syndrome. Skin lesions: The most common are sebaceous cysts, and common locations are the face, scalp, upper and lower limbs.

Treatment of intestinal polyps: Untreated colorectal polyps in patients with Gardner syndrome have a high possibility of malignant transformation, with almost 100% malignant transformation, and the average age of malignant transformation is 36 years old. Therefore, preventive colorectal resection should be performed for patients with multiple colorectal polyps detected by fiberoptic colonoscopy. Treatment of desmoid tumors: The treatment of desmoid tumors is controversial. Current recommendations are based on the experience of a small number of familial cases of hereditary adenomatous polyposis associated with and sporadic desmoid tumors. Treatment methods mainly include surgery, chemotherapy and radiotherapy. Treatment of other complications: Patients with osteomas and odontoma that are symptomatic or affect their appearance should be treated surgically, and other soft tissue tumors of the skin can also be surgically removed.

Gardner syndrome is an autosomal dominant genetic disorder. The probability of their offspring being affected is 50%. Patients and high-risk individuals should undergo genetic testing: family members of those with APC gene mutations should undergo genetic screening and follow-up. Clinical examination of gene carriers should begin at age 5 years, with annual full colon or sigmoidoscopy until age 65 years.

Eat more vitamin-rich foods and try to reduce spicy and irritating foods. Keep warm, avoid cold and wind, maintain a regular daily routine, avoid overwork and lack of sleep, and quit smoking and drinking. Eat more bamboo attached foods such as bamboo fungus, bamboo shoots, etc., which have high fiber content, can promote gastrointestinal peristalsis, and can also improve the body's immunity, thus promoting the repair of joint pain. Eating more foods rich in selenium has a good nourishing effect on lung function and can also reduce the risk of tumor diseases.