The isolated objects are transported to designated places (such as isolated hotels) by the local epidemic prevention department in a closed loop for centralized isolation medical observation and management. All isolated objects are not allowed to contact with other observed objects during the observation period, and in principle they are not allowed to leave the isolation room. According to the requirements of epidemic prevention, monitor body temperature and health status every morning and evening, collect nucleic acids regularly, and do a good job of indoor daily disinfection. After the isolation is lifted, you can decide your own travel activities.