Hello: Serum creatinine reaches 360 umol/L. Considering diabetic nephropathy, it is recommended to check urinary microalbumin. If diabetic nephropathy is diagnosed, it is suggested to strengthen the treatment with insulin pump and control the blood sugar within the ideal range, that is, strictly control the blood sugar and don't let the drugs cause damage to the kidney. In addition, traditional Chinese medicine decoction and enema therapy are needed. Of course, everyone's situation is different, so the treatment must be individualized. If the blood lipid is not well controlled for a long time, it will lead to atherosclerosis and hypertension, which will easily lead to diabetic cardiovascular and cerebrovascular diseases. In order to prevent atherosclerosis at an early stage, it is necessary to maintain normal blood lipids, reduce blood viscosity, and maintain normal blood pressure and weight. Therefore, diabetic patients should also regularly check their blood lipids, blood viscosity, blood pressure and weight. In the final analysis, diabetes is to damage the big blood vessels of the whole body, which will be complicated with cardiovascular and cerebrovascular diseases and diabetic foot; Microvessels can be complicated with diabetic nephropathy and diabetic retinopathy. Once complications occur, it means that the condition is very serious. We often say that diabetes is not terrible, but its complications. The complications of diabetes are subtle and develop slowly. Chronic complications are terrible, but they will be well controlled as long as they are treated regularly. I suggest you go to a diabetes specialist hospital for comprehensive treatment. Don't think that taking some hypoglycemic drugs can control your illness. I wish you a speedy recovery!