Urticaria is a common skin allergic disease. The main performance is that the skin suddenly itches, and then bright red or pale white wind masses appear, which come and go like the wind, spread all over the body quickly when they come, and disappear quickly after a few hours, but as soon as the old wind masses disappear, new wind masses come again, one after another, repeatedly many times a day. Urticaria that does not heal for several months will become chronic. About 15% ~ 20% people have at least once in their lives, and it can happen at any age.

So, why is urticaria so difficult to treat?

Etiology of urticaria

Urticaria is an abnormal immune response caused by external environmental factors. Mainly due to the disorder of immune response mechanism, the body interacts with antigen substances to produce specific antibodies (such as IgE and IgA antibodies), which, if combined with re-entered antigens, can lead to antigen-antibody reaction, leading to the release of inflammatory mediators by mast cells and basophils, resulting in physiological dysfunction and tissue damage, mainly manifested as wheal.

It is difficult to change the environment, such as the fluttering of pollen, the amount of dust, the level of temperature and humidity, and whether there is a special body odor, which may induce allergies.

There are many foods with allergens, such as eggs, milk, wine, peppers, cabbage, seafood and so on. Even frozen products are possible.

Infection can also lead to duplication. Sometimes it's okay, and the result is an allergic reaction, because skin infection, which may be caused by viruses or bacteria, stimulates tissues and cells.

Urticaria also has genetic factors. One of the causes of urticaria is genetic factors, so some parents with a history of urticaria are likely to pass it on to their children, which is also relatively common. Many children of several years old have symptoms of urticaria. Asking about the medical history shows that both his parents have some history of urticaria.

How to treat urticaria?

1. First, find the cause.

Recall the situation before the onset, including special food, drugs, changes in the surrounding environment, climate impact, personal living habits, mental state and whether there are other diseases. , provide clues, with the help of doctors, analyze which allergens are most likely to suffer from the disease, line up in turn, and then try not to contact or less contact with possible allergens. If the lesions and symptoms are alleviated or disappeared, it is proved that the suspected substance may be an allergen in turn. For example, after careful memory, patients find that it is likely to be caused by certain foods, so they should stop all foods that they don't eat often, start with the simplest foods that generally don't cause allergies, and supplement one food every few days. When it is added to food that suddenly causes urticaria, they should be highly suspicious of it, then stop the food, and the urticaria will disappear and try again if necessary. If the same result occurs, food is undoubtedly the "curse" of urticaria. You should avoid eating this kind of food in the future.

2. Immune antiallergic therapy

Urticaria mostly belongs to type I immune allergic reaction. When allergen enters human body, it will stimulate blood to produce IgE antibody. After the concentration of this antibody in blood is greatly increased, it can cause strong resistance of immune cells such as mast cells and eosinophils, thus releasing allergic inflammatory mediators such as histamine and leukotrienes, leading to allergic reactions in human bodies. These inflammatory mediators are over-secreted due to the increase of IgE antibody, which will damage the barrier function of human skin and mucosa and cause wheal rash or vascular edema.

Studies have shown that antihistamines and other western medicines are effective in acute treatment of allergic symptoms at present, but since Th2 cannot be inhibited, symptoms will reappear as long as drugs are stopped. If we want to balance immune cells and inhibit Th2, we can use Xinmin Kang anti-allergic probiotics to regulate it. Xinminkang, an antiallergic probiotic, can participate in IgE-mediated immune allergic reaction. Co-culture of human dendritic cells with anti-allergic probiotics * * * has an effect on the immunity of Th 1 regulated by interleukin (IL- 12), thus screening an anti-allergic probiotic strain with anti-allergic ability. Using active and non-pathogenic microorganisms to improve the ecological balance of intestinal microorganisms, the largest immune organ of human body, and then promote the immune tolerance function. After continuous supplementation for more than three months, the concentration of IgE in the body decreased, so that allergens could not combine with IgE antibodies in the body, and thus allergic series of biochemical reactions no longer occurred.

3. Insist on strengthening physical fitness and improving immunity.

Insist on proper physical exercise every day, develop good living habits, eat lightly, work and rest regularly, avoid overeating and often stay up late, and keep healthy. It is a good way to reduce the probability of urticaria by improving immunity and enhancing one's disease resistance.

4, diet, don't blindly avoid eating.

Many foods are really the cause of urticaria. When we find these induced foods, we should avoid eating them again. Many times, we can't find it for the time being. Doctors often warn patients to avoid eating some common allergic foods, such as fish, shrimp, crabs and other seafood, as well as beef and mutton, which is called taboo. But don't be blind. After individual patients get urticaria, their daily diet is rice porridge except cabbage and radish, as if all foods will be allergic to him. Miss Liu adopted this method, which is a very bad taboo method. Not only can we not find allergens fundamentally, but it will also affect the nutritional intake of patients themselves, which will lead to malnutrition in the long run.

Urticaria patients should be conscientious people in their daily lives, that is, carefully observe which foods can induce allergies and which foods can't. For foods that don't cause allergies, it's not necessary to "throw away my food bar and cup, I can't eat or drink, pull out my chopsticks and look around". For foods that seem to be allergens, we should also carefully test and observe them. For example, a patient with urticaria was allergic to grilled fish fillets once, thinking that he was allergic to this kind of fish. Later, he ate this kind of boiled fish and found no allergy. Careful observation, it turned out that he was allergic to the seasoning in the grilled fish fillet. So there is no need to blindly avoid eating, but you must be a conscientious person, and food will not stay away from urticaria patients.