The reward for a drug test is at least 1-2K and at most tens of thousands, depending on the drug risk, cycle and blood collection. In order to avoid the interaction between the two drugs, the law stipulates that only one drug test can be taken every three months.
At present, the health projects in the first stage can be roughly divided into the following categories:
1. Drugs on the market: These drugs are designed to evaluate the efficacy of two identical drugs, and their safety has generally been confirmed;
2. Foreign listed domestic unlisted drugs: When these drugs enter the China market, it is necessary to confirm their safety and metabolism in China population. Because of racial differences, it is necessary to do related safety drug research; Security is generally acceptable;
3. Innovative drugs: this is a new drug, and its safety is still being explored, so it can enter clinical medicine; Early observation in animal research.
It is a three-point poison, but the probability of serious side effects is very low. The dosage of the tested drug is low and the time is short. Take only one pill at a time, usually twice, with an interval of about a week. Each drug test item has different requirements for the subjects. Generally, the blood measurement is about 150ml, which has no influence on the human body. Generally, the blood donation amount of 200 ml-400 ml is much less than the blood measurement of blood donation. It is medically recognized that a small amount of blood donation is beneficial to human health!
The experimental base of each hospital is a national demonstration and approval base, and the medical equipment and technology are advanced and first-class! In case of emergency, you can take emergency measures quickly! In addition, it should be emphasized that the state attaches great importance to the safety of medication, and there are relevant laws and regulations to protect subjects; As the implementer of the experiment, the hospital will hold an ethics Committee with the participation of doctors, experts and the public before the consistency evaluation. Only after full discussion and approval can experiments be carried out, that is to say, all experiments are strictly controlled. Different drugs are tested, and the degree of danger is different, but medical institutions must not let volunteers take risks.
Generally, drug testers fill in the information registration first, and then wait for the hospital to call for a physical examination. After the medical examination is completed, wait for the hospital to inform the medical examination results. If qualified, you can successfully join the group (T and R drugs are in random order, TR group or RT group. Take only one drug per cycle, imported drugs already on the market, or domestic generic drugs. There are also three cycles of projects, TRR, RRT and other group tests). Generally, one day in advance notice will be given to check into the hospital, and clothes and bags will be locked when checking in. You can only wear uniform clothes provided by the laboratory, and you can carry personal items such as mobile phones.
After taking medicine in the morning, the nurse will draw blood from the drug tester every once in a while to observe the adverse reactions. Some special experiments will use special recording methods, such as subcutaneous injection of drugs will record the reaction of the injection site with a camera, and the contrast agent will observe its changes through imaging means. In order to ensure no accidents during drug testing, accommodation and meals are arranged in a unified way, and take-away food and drinks are not allowed. The experimental period is uncertain, but on the last day of discharge, there will be a physical examination to confirm that the subjects are healthy and have not been adversely affected by drugs.
Long-term participation in drug testing experiments is the most common harm to the body. It is mainly used to bury the median elbow vein and cephalic vein of venous indwelling needle. It rarely causes phlebitis, but the venous circulation is easy to rebuild, such as the vein "can't be found" or the vein is not easy to inject.