Henoch-Schonlein Purpura Henoch-Schonlein Purpura, also known as self-limited acute hemorrhagic disease, is an allergic vasculitis that invades arterioles and capillaries of skin and other organs. The cause of the disease may be pathogen infection, some drugs, allergies, etc. This leads to the formation of IgA or IgG circulating immune complex in the body and deposits on the capillaries in the upper dermis, thus causing vasculitis.
The etiology of Henoch-Schonlein Purpura is a small vasculitis in which immunoglobulin A(IgA), C3 and immune complex are deposited in arterioles, capillaries and venules. Henoch-Schonlein purpura and IgA nephropathy are two related diseases. Both diseases have elevated serum IgA levels, and renal biopsy also has the same findings. IgA nephropathy almost only occurs in young people, and mainly involves the kidneys. Henoch-Schonlein purpura mainly occurs in children, and its symptoms can involve skin and connective tissue, joints, gastrointestinal tract, scrotum and kidney.
How to treat allergic purpura? 1, people with allergies should pay special attention. Henoch-Schonlein purpura is a common hemorrhagic disease in school-age children. Most children are allergic themselves. Under the action of some external allergens, the body has allergic reaction, causing massive vasculitis, leading to the increase of fragility and permeability of small blood vessels, and exudative purpura and edema.
2, infection, drugs, etc. It may be the cause of sensitization. The pathogenesis of the disease is not completely clear, and it is thought to be related to the autoimmune reaction mediated by an immunoglobulin called IgA in human body. Diseases caused by various bacterial, viral and parasitic infections, such as colds, tonsillitis, measles, chickenpox, rubella and intestinal ascariasis; Eat fish, shrimp, crab, eggs, milk and other foods rich in animal protein, as well as spicy foods such as pepper, wine and raw garlic; And taking antibiotics (such as penicillin, streptomycin, chloramphenicol, cephalosporin, etc. ), antipyretic and analgesic drugs (salicylic acid, phenylbutazone, etc. ), sedatives, sulfonamides, atropine, etc. , can be a pathogenic factor. In addition, some children are prone to allergic purpura after contact with pollen, dust, colds, mosquito bites or vaccination.
3, the condition can be light or heavy. The disease has obvious seasonality. Generally, it happens more in winter and spring and less in summer. Most children will have general malaise, low fever, fatigue and upper respiratory tract infection before onset 1~2 weeks, followed by skin purpura, which is more common in lower limbs, ankles and buttocks.
4, self-limited diseases, no preventive prescription. At present, the disease is mainly based on symptomatic and supportive treatment, including bed rest in acute stage, choosing appropriate antibiotics for infected people, and avoiding and eliminating allergic factors. Only skin purpura symptoms can be treated with compound rutin, calcium, vitamin C and antihistamines. If you have symptoms of fever and arthritis, you can use corticosteroids; For recurrent and severe Henoch-Schonlein purpura nephritis, immunosuppressants can be added. The disease is self-limited. Most children have a good prognosis, and some of them may recur in a few weeks or months. Therefore, after getting sick, you must follow the doctor's advice and review it on time.
Peanut coat soup, a prescription for treating allergic purpura, consists of 50 grams of peanut coat and 50 grams of red dates. Usage: decoct the first two herbs in water, daily 1 dose, twice. Efficacy: enriching blood, cooling blood and stopping bleeding. Indications: Henoch-Schonlein purpura is a blood-heat type rash with cyanosis or plaque, fever, thirst, red tongue with ecchymosis, yellow fur and rapid pulse.
Malan egg: Ingredients: 60g of Malantou whole grass, 2 green shell duck eggs. Usage: Cook the two flavors together. Boil the eggs, shell them, and then cook them until they are black. Eat egg soup, daily 1 dose, on an empty stomach. Efficacy: clearing away heat, cooling blood and stopping bleeding. Indications: Henoch-Schonlein purpura is a blood-heat rash with purple spots on the skin, accompanied by fever, thirst, constipation, red tongue and yellow fur.
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