About 285.5 kilometers and about 303.3 kilometers. According to Baidu Maps, the total driving distance from Sanya City to Haikou City is about 285.5 kilometers, which takes about 3 hours and 25 minutes. It passes through the Hainan Island Ring Expressway.

Another self-driving route from Sanya City to Haikou City is about 303.3 kilometers, takes about 3 hours and 33 minutes, and passes through: Shanhai Expressway and Haisan Expressway.