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Causes of high alkaline phosphatase in children

Reasons for high alkaline phosphatase in children

Reasons for high alkaline phosphatase in children are divided into physiological reasons and pathological reasons.

1. Physiological reasons

Children who are in the growth and development period have very active alkaline phosphatase in bone tissue and have high levels of alkaline phosphatase. Condition.

2. Pathological causes

If the baby has bone disease, severe anemia, cholestatic hepatitis, obstructive jaundice, primary liver cancer, etc., it will cause high alkaline phosphatase phenomenon.

What is alkaline phosphatase

Alkaline phosphatase is an enzyme that is widely distributed in human liver, bones, intestines, kidneys, placenta and other tissues and is excreted out of the bile through the liver. . This enzyme is not a single enzyme but a group of isoenzymes.

Alkaline phosphatase is an indicator of liver function test. When the liver is damaged or damaged, it enters the blood through lymphatic channels and liver sinusoids. At the same time, due to intrahepatic bile duct bile excretion disorder, it refluxes into the blood and causes Causes a significant increase in serum alkaline phosphatase. What is the normal value of alkaline phosphatase?

The normal value of alkaline phosphatase in women: 1-12 years old, less than 500U/L; older than 15 years old, 40-150U/L.

Normal alkaline phosphatase values ??for males: less than 500U/L for 1-12 years old; less than 750U/L for 12-15 years old; 40-150U/L for older than 15 years old. What to do if children have high alkaline phosphatase

High alkaline phosphatase in children is mostly a sign of calcium deficiency. For example, if only the blood and bone alkaline phosphatase index is high, there are also high blood phosphorus and blood calcium. or low, the possibility of calcium deficiency should be considered and combined with the child's physical examination. It is recommended that the baby be checked for trace elements. If the baby is diagnosed with calcium deficiency, vitamin D and calcium supplements should be supplemented under the guidance of a doctor and reviewed regularly. Iron deficiency should also be supplemented with iron supplements based on the results of the physical examination. Take your baby to bask in the sun more often and add more calcium-rich foods.