Its curative effect on bacillary dysentery is better than chloramphenicol and furazolidone. Andrographis paniculata extract has strong antibacterial activity against coagulase-negative staphylococcus. Andrographolide can obviously inhibit the secretion of Pseudomonas aeruginosa, the activities of extracellular proteolytic enzymes and elastase, and inhibit the production of virulence factors of Pseudomonas aeruginosa, thus achieving the anti-infection effect.