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Scutellaria baicalensis has inhibitory effects on both cellular immunity and humoral immunity. Intraperitoneal injection of aquatica decoction into mice for 7 consecutive days can reduce the lymphocyte value, the Ea and Et rosette formation rate, the antibody serum titer, and the positive rate of acridine orange fluorescence staining of intracellular DNA and RNA. .
It also has an inhibitory effect on non-specific immune function. The water decoction of Trichosanthes striata has an inhibitory effect on the phagocytosis function of mouse peritoneal macrophages, reduces the activity of serum lysozyme, and reduces the weight of the thymus and spleen.
Anti-inflammatory.
The decoction of Xitong Pills can significantly inhibit the swelling of formaldehyde-induced and egg white-induced arthritis when administered to rats. Daphne glycolic acid, daphne glycolic acid, and daphne glycolic acid all have anti-inflammatory effects. ? The diterpenoids contained in Trichoderma striata L. can be significantly inhibited in swelling of the soles of the feet if administered to rats.
Dilate blood vessels and lower blood pressure.
This product has the effect of dilating blood vessels. The extract can significantly relax the blood vessels of rabbit ears with preserved nerves, and block the vasoconstrictive reaction caused by stimulating nerves.
This product has antihypertensive effect. After intraperitoneal injection of water decoction into cats, the blood pressure gradually dropped after 10 minutes, which lasted for 1.5 hours. Diterpenoids such as adenosine glycolic acid are its active ingredients.
Improve microcirculation and anti-thrombosis.
Trichosanthes miltiorrhiza solution has a promoting effect on the blood flow recovery of mesenteric microcirculation in mice, which is equivalent to Salvia miltiorrhiza injection. ? Intravenous injection into rabbits can significantly inhibit thrombosis. Significantly reduce the wet weight of thrombus.
Others.
(1) Darutoside has obvious anti-early pregnancy effect in rats.
(2) Antibacterial and antimalarial. In in vitro tests, wormwood has inhibitory effects on Candida albicans and Staphylococcus aureus. The water decoction has obvious inhibitory effect on murine Plasmodium.
Identification application.
Both Wutong and this product can treat rheumatic arthralgia, rubella eczema, and skin itching. However, Fungi is good at dispelling rheumatism in the muscles and bones, and can cure stroke paralysis; while Wutong can also calm liver yang and treat dizziness and headache caused by liver yang.
(3) Meridian tropism of the nature and flavor of wormwood
Bitter and cold nature and flavor.
① "Tang Materia Medica": "Bitter, cold, slightly toxic."
② "Ben Jing Feng Yuan": "Bitter, slightly pungent, cold, slightly toxic."
Returns to the liver, spleen and kidney meridians.
① "Lei Gong Pao Pharmaceutical Properties": "Enter the liver and kidney meridians."
② "Compendium of Materia Medica": "Start into the Shaoyang meridian of the hands and feet."
③ "Compendium of Materia Medica": "Enter the heart and spleen meridians."
Compatible application of Trichosanthes lucidum
With Pittosporum bark, it has the functions of dispelling wind, dehumidification, and clearing air. Benefits blood vessels and lowers blood pressure. It can treat rheumatic arthralgia, weak muscles and bones, joint pain, numbness of limbs, hemiplegia or sequelae of polio.
With Clematis, the effect is even greater. It can cure rheumatism, muscle and bone pain, numbness of limbs, etc.
Combined with Wutong, the effect of dispelling rheumatism and promoting blood circulation is enhanced. It can cure rheumatic arthralgia and numbness.
Recipe preparations
Fungus Powder ("Compilation of Living People's Prescriptions"): Any amount of Fungi grass, remove the stems and take the leaves, dry them in the sun, and age them with wine Mix thoroughly, steam and dry in the sun, mix and steam again, do the same nine times, dry in the sun, turn into fine powder, store and drink, make honey pills, swallow 12 to 15 grams in the morning with warm wine. It can be used to treat paralysis caused by wind, cold, and dampness, resulting in blood clots, numbness in the limbs, soreness in the waist and knees, and coal in the stool. Regardless of gout, painful numbness, damp phlegm, or wind-heat, it is suitable to take it for a long time to prevent strokes. Fistula disease.
Xitong Pills ("Collection of Health Preservation Experiences"): 500 grams of Indus sycamore (flowers, leaves, stems, and seeds. Chopped and dried, fried, and ground into powder), Fungi (fried, Momozi) 240 grams. The two flavors are mixed together and the honey pill is as big as a tung seed. Take 12 grams of boiled soup in the morning and evening, or use 60 grams of Wutong alone. Decoct the soup and drink it, drink it with wine, take ten doses in a row, and the pain will cause scabies, or decoction the soup and wash your hands and feet. Avoid eating pork liver, sheep blood, tomatoes, etc. Treat rheumatism, or excessive drinking and wind, internal dampness and external pathogens, which spread to the limbs and veins, causing congestion and discomfort.
As a result, the two feet are sore and painful, unable to walk, or the hands are tied and unable to lift up. People who work hard often suffer from this disease, which looks like wind paralysis.
Recipe for treating back sores ("Qiankun Business Secret"): Divide wormwood, five-leaf clover (i.e. five-leaf clover), wild safflower (i.e. thistle), and garlic into equal parts. Beat it to pieces, add a bowl of hot wine, twist the juice and drink it to get the sweating effect.
The prescription for treating carbuncle, swollen poison, and all malignant sores ("Qiankun Business Secret Yun") is 30 grams of wormwood (picked during the Dragon Boat Festival), 30 grams of frankincense, and 15 grams of alum (burned). For the end. Take 6 grams each time, mix it with hot wine, and for those with severe poisoning, take three times in a row to achieve wonderful sweating.
Huosong Pills ("Effective Prescriptions of World Medical Practitioners"): When Huo Feng lacks grass, it is made into powder, vinegar paste pills, Wu Zi Da. Take 30 pills each time with white soup. Cure gastrointestinal diarrhea.
Cure various diseases such as stomach upset and spleen problems. Recipe for abdominal pain and diarrhea ("One Hundred and One Selection Prescriptions"): Take a small amount of chopped green onion (i.e. Huofucao flower) with wrinkled noodles, bake it into fine powder, and boil the honey batter into pills, as big as sycamore seeds. Take 50 pills each time, delivered from the soup, at any time.
Polygonum multiflorum and longevity pill ("Shi Bu Zhai Medical Book"): Polygonum multiflorum, Ligustrum lucidum, Eclipta, Eucommia ulmoides, Cuscuta, Eucommia ulmoides, Achyranthes bidentata, mulberry leaves, silver flowers, rehmannia root, mulberry , golden cherry, black fat and hemp. Indications: Yin deficiency and blood deficiency, soreness and weakness of waist and knees, dizziness and dark eyes, tinnitus, insomnia, premature graying of beard and hair.
Recipe for treating intestinal wind and blood ("Fang Yong Zhengzong"): This product is made by steaming it with wine. Refined honey pills. Take 9 grams each time with white soup.
The attached recipe of Trichosanthes lucidum
Treats paralysis caused by wind, cold, and dampness, resulting in coagulation of blood vessels, numbness of limbs, soreness of waist and knees, dryness and constipation in the stool, regardless of Gout, painful paralysis, dampness and phlegm, wind-heat, suitable for long-term use to prevent stroke, impotence and paralysis: No matter how much or small the grass is, remove the stems and take the leaves, dry them in the sun, mix them with old wine, steam them and dry them in the sun, mix them and steam them again , follow the method nine times. Dry it in the sun and make it into fine powder. Store it and drink it as honey pills. Take four or five qian in the morning with warm wine and swallow it. ("Huoren Prescription Collection" Xipu Powder)
Treats rheumatism, or addiction to drinking and wind, internal dampness and external evils, which spread to the veins of the limbs, causing congestion and discomfort, resulting in Feet are sore and painful, unable to walk, or hands are tied and unable to lift up. People who work hard often suffer from this disease, which looks like wind paralysis: Indus sycamore (flowers, leaves, stems, and seeds can be cut into pieces and dried in the sun One kilogram, stir-fried, ground into pieces), eight taels of water chestnuts (fried, ground into pieces). The two flavors are mixed together and the honey pill is as big as a tung seed. Take boiled boiled soup in the morning and evening for four qian, or just use two liang of smelly sycamore, decoct the soup and drink it, drink it with wine, and take ten doses in succession. Avoid eating pork liver, sheep blood, tomatoes, etc. ("Collection of Health Preservation Experiences" Xitong Pills)
To treat wind and weak feet: Xiantong Herba (take the red stems in May, dry them in the shade, steam them with clean leaves and honey wine for nine times and dry them in the sun) one pound, Angelica sinensis , one liang each of peony and hot rehmannia root, six qian of Chuanwu (made from black beans), one liang each of Qianghuo and Fangfeng. For the end, honey pills. Take two qian each time, drink it with warm wine. ("Zhang's Medical Tong" Xichu Pills)
Treatment of stroke symptoms such as deviation of the mouth and eyes, paralysis of the hands and feet, astringent speech, drooling at the corners of the mouth, strong muscle and bone spasms, weakness of the waist and feet: Xipu (steamed with wine, Sun-dried nine times) three pounds, two pieces of akidonia, eight liang each of ginseng, astragalus, wolfberry, Sichuan bark, Atractylodes rhizome, and Angelica sinensis, four liang each of Xanthium fructus, Chuanxiong, Wei Lingxian, and Pinellia ternata (all the above medicine, but stir-fry with wine), two liang of agarwood (without fire). ***The thirteen flavors are all in fine powder, and the refined honey pills are as big as sycamore seeds. Take three qian each morning and evening, and give it white soup. ("Fangmai Zhengzong")
To treat malaria: one or two wormwood (dried). Take one dose a day, decoct it twice, and take it for three days. ("Selected Exhibition·Infectious Diseases")
To treat acute jaundice-type infectious hepatitis: five qian of goldenrod, one qian of mountain gardenia, and two rusty nails. Depending on the condition, an appropriate amount of Pseudomonas trifoliate can be added. Add 800 ml of water and cook to 300 ml. One dose per day, decoction twice. ("Selected Collection of the Whole Exhibition·Infectious Diseases")
To treat back sores: Trichoderma striata, five-leaf clover (i.e., five-clawed dragon), wild safflower (i.e., thistle), and garlic are divided into equal parts. Beat it to pieces, add a bowl of hot wine, twist the juice and drink it to get the sweating effect. ("The Secret of Qiankun Business")
To treat carbuncle, swollen and poisonous sores, and all malignant sores: one tael of wormwood (picked during the Dragon Boat Festival), one tael of frankincense, and half a tael of alum (burned). For the end. Take two qian for each dose, mix it with hot wine, and for those with severe poisoning, take three doses in a row to achieve wonderful sweating.
("Secrets of Qiankun Business")
To treat spider bites, dog bites, and other insect bites: wormwood, mash it and apply it to the affected area. ("Secret Prescriptions of Traditional Chinese Medicine in Guizhou Province")
To treat gastrointestinal diarrhea: Huomeicao, in powder form, vinegar paste pills, Wuzi Da. Take 30 pills each time with white soup. ("Huokan Wan" in "Shiyi Dexiao Prescription")
To treat various diseases of the stomach and spleen, abdominal pain and diarrhea: Wrinkle ground green onion (i.e. Huomei grass flowers), not too much, roasted, for Finely mince and boil the batter with honey into balls, as big as sycamore seeds. Take fifty pills and white soup every time, no matter the time. ("One Hundred and One Prescriptions")
Epistaxis: 100 grams of wormwood, 50 grams of Agrimony, and 20 grams of Rehmannia glutinosa. Decoction in water and take twice in the morning and evening for 5 days.
Suppurative arthritis: 100 grams of wormwood, 50 grams of white fresh bark, 30 grams of cork, and 20 grams of Achyranthes bidentata. Add about 2000 ml of water to the medicine, boil it for 20 minutes, fumigate and wash the affected area for one hour, twice a day, one dose a day.
Vitiligo: 150 grams of wormwood, grind into fine powder, and make pills with honey. 9 grams each time, taken in two portions, with rice wine or boiled water on an empty stomach.
Rheumatoid arthritis: 30 grams of wormwood, 20 grams of pittosporum bark, and 30 grams of honeysuckle. Decoction in water, one dose daily.
Acute jaundice hepatitis: 15 grams each of wormwood and artemisia, and 10 grams of gardenia. Take one dose per day, decoction in water.
Numbness of limbs: 15 grams of wormwood, 15 grams of papaya, 10 grams of saposhnikovia, 10 grams of Acanthopanax bark, and 3 grams of safflower. Take one dose per day, decoction in water.
Hypertension: 30 grams of Rhizoctonia striata, 10 grams of Gastrodia elata, and 15 grams of Uncaria. Decoction in water and take twice. One dose per day, 30 days as a course of treatment.
Prostatitis: 30 grams of wormwood, 20 grams of litchi core, 10 grams each of Ligusticum chuanxiong and Achyranthes bidentata. Put the medicine into a medicine jar, add an appropriate amount of water, soak for 5-10 minutes, decoct in water to extract the juice, and pour it into a bathtub for a sitz bath. Twice a day, 20-30 minutes each time, one dose a day for 2-3 months.
Anal itching: 12 grams each of wormwood, purslane, lithospermum, Houttuynia cordata, and kochia chinensis, 15 grams of cnidium monnieri, 9 grams of white asparagus, and 10 grams of alumen. Decoction the juice and take a sitz bath, twice a day, 20 minutes each time, one dose a day.
Side effects of Trichosanthes lucidum
Adverse reactions
(1) Traditional literature
"Compendium of Materia Medica": Slightly toxic. [Shizhenri] "If you take it raw and pound the juice, it will make people vomit. So it is slightly poisonous. Nine steaming and nine exposures will nourish people and remove paralysis, so it is non-toxic. When it is raw, it is cold in nature, and when it is cooked, it is warm in nature."
(2) Toxicology test
LD50: The LD50 of intravenous injection of water decoction and alcohol precipitate into mice is 45.54g/kg-+-1.44g/kg. The maximum tolerated dose of intraperitoneal injection in mice is 400 times that of humans.
It shows that the toxicity is very small.
(3) Clinical observation
Non-toxic. There is no obvious discomfort when taking it as a decoction in water within the normal dosage. Excessive dosage may cause reactions such as nausea and loose stools. The so-called minor poison, Li Shizhen has pointed out, is the digestive tract discomfort caused by excessive dosage. Therefore, when using in large doses, it is advisable to use more stomach-friendly medicine to reduce gastric discomfort.
Note
People with insufficient Yin blood should not take it.
"Tang Materia Medica": "Too much will make people vomit."
"Compendium of Materia Medica": "All patients suffer from paralysis of the limbs, pain between bones, weakness in the waist and knees, due to swelling. , kidney deficiency, insufficient yin and blood, not caused by rheumatism, should not take it. "
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