qīng fēng téng
2 English ReferenceSinomenium acutum Rhed. et Wils. Wils. [Landau Chinese-English Dictionary]
caulis sinomenii [Xiangya Medical Dictionary]
orientvine stem [Xiangya Medical Dictionary]
sinomenii,caulis [Xiangya Medical Dictionary]
Sinomenium acutum [Sinomenium acutum,Caulis]. Sinomenium acutum [Xiangya Medical Dictionary]
orientavine [21st Century Bilingual Dictionary of Science and Technology]
Caulis Sinomenii(La) [Nomenclature Review Committee of Chinese Medicine. Chinese Medicine Nomenclature (2004)]
orientvine vine [Chinese Medicine Nomenclature Validation Committee. Chinese Medicine Nomenclature (2004)]
3 OverviewOrivine vine is the name of a traditional Chinese medicine (TCM), which can be found in the Journal of Traditional Chinese Medicine (中藥志). It is the dried vine stem of Sinomenium acutum (Thunb.) Rehd. et Wils. and Sinomenium acutum (Thunb.) Rehd. et Wils. var. cinereum Rehd. et Wils. of the plant family Fangji [1].
The Pharmacopoeia of the People's Republic of China (2010 edition) contains pharmacopoeial standards for this herb.
4 Latin nameCaulis Sinomenii (La) (Nomenclature of Traditional Chinese Medicine (2004))
5 English nameorientvine vine (Nomenclature of Traditional Chinese Medicine (2004))
6 Alias of Qingfengteng (青风藤)Qingfengteng (清清藤), Fengfengteng (寻風藤), Qingjiao Er (青绳儿), Bone Chasing (追骨風), and Dafengteng (大风藤)[2].
7 SourceQingfengteng is the stem and vine of Sinomenium acutum (Thunb.) Rehd. et Wils. or S. acutum (Thunb.) Rehd. et Wils. var. cinereum Rehd. et Wils. in the family of Fangji [2].
8 OriginQingfengteng is mainly produced in Hubei, Jiangsu, Zhejiang and other places [2].
9 Flavor and MeridianQingfengteng is bitter and pungent in taste, and flat in nature; it belongs to the liver and spleen meridians[2].
10 Functions and IndicationsQingfengteng has the effect of dispelling wind, removing dampness and relieving pain, treating rheumatism and paralysis, crane's knee wind, calendar wind, paralysis of the limbs, itching, oedema, swelling and pain in the feet, sciatica, trigeminal neuralgia [2].
11 Qingfengteng dosageDecoction: 9 ~ 15g [2].
12 Chemical constituents of Cymbopogon flexuosusCymbopogon flexuosus stems and roots contain alkaloids such as chikungunin alkaloids, bataglinine, 8,14 dihydropolypodophyllinine, cymbopogonine, isocymbopogonine, tudorine, scavenging alkaloids (Sinoacutine), bis-cymbopogonine, as well as butyric acid resins such as syringaresinol, β-sitosterol, and leguminous stanol[2].
13 Pharmacological effects of Cymbopogon flexuosusCymbopogon alkaloids have analgesic, sedative, analgesic, antihypertensive, and anti-inflammatory effects in a variety of animals, but also have significant histamine-releasing side effects[2]. Oral administration to dogs and monkeys often results in mild gastrointestinal adverse effects[2].
14 Qingfengteng Pharmacopoeia Standard 14.1 NameQingfengteng
Qingfengteng
SINOMENII CAULIS
14.2 SourceThis product is the plant of the family of preventive medicine, Qingfengteng, Sinomenium acuturn (Thunb.) Rehd.et Wils. and hairy Qingfengteng. Sinamenium acutum (Thunb.) Rehd. et Wils. var. cinereum Rehd. et Wils. is the dried vine stem. Harvested in late fall and early winter, tied or cut into long pieces, sun-dried.
14.3 PropertiesThe product is long cylindrical, often slightly curved, 20-70cm or longer, 0.5-2cm in diameter, the surface greenish brown to brown, some gray-brown, with fine longitudinal lines and lenticels. The nodes are slightly expanded. There are branches. Light, hard and brittle, easy to break, uneven section, gray-yellow or light gray-brown, narrow cortex, xylem rays arranged in a radial pattern, pith yellowish white or yellowish brown. Gas slightly, taste bitter.
14.4 Identification(1) cross-section of the product: the outermost layer of the epidermis is covered with a thick cuticle, or cork layer. Cortex scattered fibers and stone cells. Fiber bundles in the column sheaths are crescent-shaped, often with 2-5 columns of stone cells on the inner side, and extend tangentially to the rays of the stone cells in the group connected to form a ring. The vascular cambium is externally tough. The bast rays are broadened outward, and conical or branched stone cells are seen; most of the bast cells are decadent, and some of them have one to three scattered fibers. Xylem ducts single scattered or several tangentially connected. Medullary cells with slightly thicker walls and conspicuous pores. Thin-walled cells contain starch grains and calcium oxalate needle crystals.
Powder yellow-brown or gray-brown. The epidermal cells are yellow or yellowish brown, orbicular or square in cross-section, 24-78 μm in diameter, and covered with cuticle. The stone cells are yellowish or yellow, square, pike, ellipsoid or irregular, with thick walls and obvious pore grooves. Cortical fibers yellowish or yellowish, 27-70 μm in diameter, with extremely thick walls and narrow lumen. Calcium oxalate needle crystals were fine and present in the thin-walled Maillard cells.
(2) Take 2g of powder, add 25ml of ethanol, heat and reflux for 1 hour, filtration, filtrate evaporation, residue with 1ml of ethanol to dissolve, as a test solution. Take alkaloids as control, add ethanol to make a solution containing 1mg per 1ml, as the control solution. According to the thin layer chromatography (Appendix VIB) test, absorb the above two solutions of 5μl, respectively, point in the same silica gel G thin layer plate, with toluene, ethyl acetate, methanol, water (2:4:2:1) 10 ℃ below the upper layer of the solution as the unfolding agent, placed in concentrated ammonia pre-saturated for 20 minutes of the unfolding cylinder to unfold, take out, air-drying, and sprayed in turn with bismuth iodide potassium test solution and sodium nitrite ethanol test solution. In the chromatogram of the test product, in the corresponding position with the chromatogram of the control product, the same color spots.
14.5 Check 14.5.1 MoistureNot more than 13.0% (Appendix IXH first method).
14.5.2 Total ashnot more than 6.0% (Appendix IX K).
14.6 Determination of contentDetermined by high performance liquid chromatography (Appendix VID).
14.6.1 Chromatographic conditions and system suitability testOctadecylsilane-bonded silica gel as filler; methanol-phosphate buffer (0.005 mol/L disodium hydrogen phosphate solution, 0.005 mol/L sodium dihydrogen phosphate adjusted pH to 8.0, and then adjusted pH to 9.0 with 1% triethylamine) (55:45) as the mobile phase; detection wavelength of 262nm. The theoretical plate count should be not less than 1500 according to the peak of alkaloids.
14.6.2 Preparation of control solutionTake the appropriate amount of alkaloids, weigh it precisely, and add methanol to make a solution containing 0.5 mg per 1 ml, that is, obtained.
14.6.3 Preparation of test solutionTake about 0.5g of powder (sieved), weigh it precisely, put it in a stoppered conical flask, add 20ml of 70% ethanol, stopper it tightly, weigh it, ultrasonic treatment (250W, 20kHz) for 20 minutes, let it cool down, then weigh it, and make up for the loss of weight with 70% ethanol, shake it well, filter it, and take the filtrate. The filtrate, that is obtained.
14.6.4 DeterminationPrecisely suck up 5μl each of the control solution and test solution, inject into the liquid chromatograph, measurement, that is, obtained.
This product contains not less than 0.50% of cycloheximide (C19H23NO4) calculated as dried product.
14.7 Qingfengteng tablets 14.7.1 ConcoctionRemove impurities, slightly soaked, moistened, cut into thick slices, dried.
The product is in the form of thick slices of round shape. The outer surface is greenish brown to brown, some grayish brown, with longitudinal lines, some visible lenticels. The cut surface is gray-yellow to light gray-yellow, the skin part is narrow, the wood part has obvious radial texture, which has most of the small holes, the pith is yellowish white to brownish yellow. Gas slightly, bitter taste.
14.7.2 InspectionMoisture is the same as the herb, not more than 9.0%.
14.7.3 Identification(except cross-section) Same as the herb.
14.7.4 Inspection(total ash) Same as the herb.
14.7.5 Determination of contentSame as the herb.
14.7.6 Flavor and attributionBitter, pungent, flat. Attributes to liver and spleen meridians.
14.7.7 Functions and IndicationsDispelling wind-dampness, clearing the channels, and facilitating urination. It is used in treating rheumatism and paralysis, swelling of joints and paralytic itching.
14.7.8 Method of use and dosage6~12g.
14.7.9 StorageIn a dry place.
14.8 Provenance