Capsaicin is an extremely pungent vanillylamide alkaloids, with a variety of complex physiological and pharmacological activities, containing P substances on some of the sensory nervous system, cardiovascular, pulmonary function, thermoregulation, gastrointestinal function has a significant impact on the anti-inflammatory and analgesic, promote fat metabolism, lachrymation and other effects, of which the more prominent is its unique long-acting analgesic effect. Capsicum extract alkaloids in the main component of capsaicin, but also contains a small amount of dihydrocapsaicin, lower dihydrocapsaicin, high capsaicin, high dihydrocapsaicin, etc., these derivatives also have similar capsaicin the same effect. Capsaicin is widely used in the treatment of arthritis, muscle pain, back pain, sports sprains and post-herpetic neuralgia. Currently, it is mainly used as a topical pain reliever, drug treatment analgesic, antipruritic, stomachic and anti-dieting agent, heart disease preventive drug, weight loss drug, pesticide, as well as for military purposes. The use of the alkali is very wide, the market outlook is very good. According to market research, the current international market price of capsaicin is 4,000 U.S. dollars per kilogram. Global annual production of capsaicinoids is only about 10 tons, the international market needs more than 50 tons per year, the market gap of about 40 tons; China's annual production of capsaicinoids is only about 1 ton, the market gap is very large.
For the extraction of capsaicinoid production methods, belong to the confidentiality of the production company, I do not have the relevant information for the time being.
Capsaicinoids are mainly used in the following fields or industries:
1. Topical pharmaceutical preparations (such as ointment containing capsaicinoids, gel, post, spray)
Capsaicinoids are made into topical dosage forms, mainly used for wind-cold pain, so that the local blood vessels of the skin reflex dilation, to promote the exuberance of the local circulation, so it has the effect of removing stasis and swelling, and facilitating blood circulation, so it has the effect of removing stasis and swelling, and facilitating blood circulation, so it has the effect of removing stasis and swelling, and facilitating blood circulation. Therefore, it has the effect of removing stasis and swelling and facilitating joints; it is also used in the treatment of diabetic complications, i.e. diabetic neuralgia; it is also used in the treatment of various skin diseases, such as pruritus.
Capsicum has a long history of application as a medicine, Chinese medicine believes that chili can "warm the cold, stomach and food". Capsaicin and ointment for analgesia has been included in the cause, Japan, Germany, Canada and other countries Pharmacopoeia, foreign countries in the early nineties of the last century, there has been capsaicin compound capsule, a single or compound ointment and other preparations, and as OTC drugs for sale, the current domestic is the light of the Bioengineering Co., Ltd. and its scientific research units are committed to the high-purity capsaicin in the field of burns, cancer pain, postoperative analgesia, research; western medicine two new drugs. Ltd. and its scientific research units are working on the research of high-purity capsaicin in the field of burns, cancer pain, postoperative analgesia, etc.; western medicine, the second class of new drugs capsaicin capsules and injections have made a breakthrough, has completed the preclinical research, is expected to replace the existing addictive other drugs, which will make a revolutionary achievement in the pain. 2. Detoxification, strong analgesic preparations
Scientific research has found that the high purity of capsaicin made of analgesic injections is a broad-spectrum efficient analgesic new drugs, due to extensive trauma, cancer, such as the late stage of severe pain especially powerful analgesic effect; and made of capsaicin detoxification injections for almost all addictions have a detoxification effect.
3. Food additive industry (flavor enhancers)
Capsicum (vegetarian) can stimulate the oral mucosa, reflexively strengthen the gastric motility, enhance the activity of digestive enzymes, which has the effect of regulating taste, promoting appetite and improving digestion.
Capsaicin in the form of low concentration products such as chili essence, chorizine as a food additive, has been widely used in the food industry. Mixed with chili red pigment, it can be used as hot pot base, cold dishes, casual food, convenience food, fast food, microwave oven food and other flavoring materials, to play the color, aroma and taste of the effect, the application is very common. Currently used as additives in the food industry, such as chili essence, chili, are low purity chili alkali products, impurities, heavy odor, low price, low economic benefits.
4. Industrial auxiliaries
Mainly used in the production of biological paint to prevent shells, algae in ships, warships and contact with seawater part of the parasites; or the production of pest control, rodent-resistant biological cables to prevent termites, rodents on the fiber optic cables, cables bite.
In the field of light industry, capsaicin can be used as a biological antifouling agent, applied to anti-fouling coatings for ships, coated on ships and offshore buildings in contact with seawater, to prevent algae, shellfish, mollusks, and other marine organisms from adhering to the replacement of organotin antifouling coatings products, so that it can be achieved to prevent the gathering of aquatic organisms in the hull of the ship. The use of synthetic capsaicin animal avoidance properties, can also be used for cable sheathing plastic functional additives, the preparation of anti-termite, anti-rodent function of the cable, fiber optic cable material.
5. Cosmetic weight loss
Capsicum (vegetarian) can improve fat metabolism, people in the eating chili pepper (vegetarian) after the production of heat, is the body fat in the "burning", so you can consume the body's excess fat, control body weight, in order to achieve the purpose of weight loss.
6. Making police equipment
Such as military, police on the explosion-proof, chaotic use of tear gas spray, female self-defense equipment.
Capsaicin has a good tear gas effect, and no toxic side effects, so it can be used in the military as the main raw material for the manufacture of tear gas canisters, tear gas guns and defense weapons in the United States, Japan and Southeast Asia and other countries have been widely used. Chorine can trigger a strong physiological reaction in the human body, causing coughing, vomiting, tearing, disorientation and erythema. It is thus used as a personal defense weapon and a tool to subdue lawbreakers.
7. In the field of bio-pesticides
The product as a new type of green pesticide has a good touch, repellent effect on crop pest control can achieve high efficacy, long-lasting and degradable characteristics, is a new type of environmentally friendly raw materials for bio-pesticides.
8. Agriculture, capsaicin can be used as pest repellent biopesticides, is the production of a new type of green environmentally friendly biopesticides "hot pepper power" of the main ingredients. Capsaicin made of microemulsion is a new type of plant source environmentally friendly bio-pesticides, pests, with high efficacy, long duration, good safety, no pollution of the environment and other characteristics, is an ideal pollution-free pesticides.
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