? Category:Symptoms

? Allergic cough is also known as allergic bronchitis or cough variant asthma, the clinical features of allergic cough is: more than two months of unexplained chronic cough, cough paroxysmal irritating dry cough, or a small amount of white foamy sputum; in the inhalation of smoke or paint, dichlorvos and other chemical odors can be exacerbated; application of a variety of antibiotics is ineffective, no obvious abnormalities in the radiographs or CT examinations. 40% of the patients can be combined with symptoms of allergic rhinitis, sneezing, runny nose, etc. Many foreign doctors call it an allergic rhinitis, which is the symptoms of allergy. 40% of patients can be combined with sneezing, runny nose and other symptoms of allergic rhinitis, many foreign doctors call it allergic rhinobronchitis.

Overview

Allergic cough, also known as atopic cough (AC), is a chronic dry cough lasting 8 weeks or more, with clear atopic factors, including elevated peripheral blood eosinophil counts, total serum IgE, and specific IgE antibodies, etc. However, lung function and airway reactivity tests are normal in these patients. Airway reactivity tests were normal, and most of the patients could be accompanied by sputum eosinophilia, which was ineffective to bronchodilators and responded well to histamine and glucocorticoid therapy. From the results of the examination, patients with allergic cough in the treatment, in the application of antihistamine drug therapy, should be aimed at the solution of elevated total serum IgE, the current anti-allergy probiotic compositions to obtain a patent anti-allergy lactobacilli, which is characterized by reducing the generation of serum IgE antibodies, has been shown that Jinfuming has the function of stimulating and regulating natural and acquired immunity.

The main triggers

The triggers of allergic cough are factors that trigger an acute attack of allergic cough and aggravate the symptoms of allergic cough on top of the allergic cough disease that the patient already suffers from.

I. Psychosocial factors

The relationship between psychosocial factors and allergic cough is also clinically important, and most allergic cough management guidelines or allergic cough management manuals pay greater attention to psychosocial factors. Studies have demonstrated that lower levels of patient education, poor adherence, and inadequate health care are associated with mortality and prevalence of allergic cough. Most authors now believe that psychosocial factors are closely related to the onset of allergic cough, and Lehrer et al. suggest that psychiatric, psychological, emotional, and personality factors should be taken into account in studies of allergic cough.

Certain studies have demonstrated that wheezing episodes can be induced in the majority of patients with allergic cough due to certain psychosomatic stresses and changes in emotional factors, which are more pronounced in adult patients, such as anxiety, anger, nervousness, panic, depression, anger, and worry, all of which can be triggers for allergic cough episodes. In addition, poor socioeconomic status (e.g., inability to afford inhaled glucocorticosteroids) and inadequate health care (e.g., lack of appropriate anti-inflammatory medications or nebulizing devices, inability to master certain allergic cough self-management techniques, and lack of guidance from a physician specializing in allergic cough or anaphylactic reactions) can seriously affect the stability of the allergic cough.

Social and familial factors such as stress from overwork, career setbacks, financial constraints, poor social and health care, and other illnesses, as well as worry and frustration due to family breakups, marital failures, or romantic breakups, can all be triggers for anaphylactic cough.

Second, climatic factors

Cold air, changes in air humidity, high and low barometric pressure can trigger an attack of allergic cough. In areas with large temperature differences, high humidity or low air pressure, the incidence of allergic cough increases significantly, and when patients with allergic cough in these areas go to areas with a dry climate and high air pressure, the allergic cough can often be relieved. The mechanism of cold air-induced allergic cough is that cold air can lead to heat loss in the airway, resulting in the release of mediators from mast cells, directly or indirectly inducing airway inflammation, causing allergic cough episodes, and the temperature is too high or too low is an unfavorable factor for allergic cough.

Based on the phenomenon that allergic cough sufferers often feel their symptoms worsen during thunderstorms, the results of a six-year survey by Robert et al. on the occurrence of thunderstorms and children's emergency hospital admissions for allergic cough confirmed the existence of "thunderstorm allergic cough". It was found that children were 15 per cent more likely to be hospitalized for allergic cough during thunderstorms. It has been suggested that an increase in airborne pollen concentration is the cause of "thunderstorm allergic cough", but Robert's study confirms that "thunderstorm allergic cough" is associated with an increase in the concentration of airborne fungal spores in thunderstorms and not with changes in the concentration of airborne pollen. However, Robert's study confirmed that the occurrence of "thunderstorm allergic cough" is related to the increase of airborne fungal spore concentration in thunderstorms, but not to the change of airborne pollen concentration. During thunderstorms, the concentration of airborne fungal spores nearly doubles.

Exercise and hyperventilation

Exercise-induced allergic cough is a common clinical occurrence, and for most patients with allergic cough, exercise is only a predisposing factor, whereas for patients with locomotor allergic cough, exercise may be the causative factor. Virtually all patients with allergic cough and some patients with allergic rhinitis may experience wheezing after a certain amount of exercise. The mechanism is related to the hyperventilation caused by excessive exercise, which results in excessive heat loss from the airways and a cooler airway environment, thereby inducing the release of inflammatory mediators from mast cells and leading to airway inflammation. Hyperventilation due to laughing and crying in children with allergic cough also often induces wheezing symptoms.

How to treat

In pediatric allergic cough, antimicrobials and cough suppressants have no significant effect, while asthma medications and antiallergics can stop the cough. Ketotifenol and salbutamol (salbutamol) should be chosen for treatment. The cough usually disappears within two to five days after treatment, but in some cases the cough disappears only after two weeks to a month or more after taking the medicine. Children with long-term coughing damage to the respiratory mucosa, damage to the mucosal tissues of the repair needs a process, the children in the removal of bronchospasm drugs and anti-allergic drugs after a longer period of time, the drug can play a role.

In addition, according to the World Health Organization's global asthma standardized treatment program, should be used stepwise, according to the severity of symptoms graded treatment. At the same time advocate the use of inhaled hormones, dilate the bronchial tubes, take anti-inflammatory, desensitizing drugs for combination therapy. Specific practices include:

1, in the alternation of seasons, sudden changes in temperature, parents should try to do a good job for the child to keep warm, to avoid cold, cold and flu.

2. Avoid foods that cause allergic symptoms, such as seafood, cold drinks and carbonated beverages.

3. Don't keep pets and flowers at home, don't lay carpet, and avoid children's contact with pollen, dust mites, fumes, paints and so on.

4, do not let the child hold long fluffy toys to sleep.

5, in the bathroom or basement, should use dehumidifiers and air filters, and regularly replace the filter.

6. Bedding should be dried often.

Allergic cough herbal prescription

Allergic cough children with paroxysmal, irritating dry cough at night, no obvious signs of upper respiratory tract infection and fever. Chinese medicine believes that it belongs to the lung qi deficiency, the treatment is advocated "urgent to treat the symptoms, slow to fix the root".

Treatment of the symptoms of the prescription:

Ephedra, tangerine red, licorice, Suzi 5 grams each, almonds, mulberry white, Poria, winter flowers, Ziyuan 6 grams each, Sagittarius 4 grams.

Dosage:

Decoction in water, 2 posts a day, to the extent that the condition is relieved.

Solid root prescription:

Astragalus, Codonopsis, Radix Rehmanniae Praeparata, Rhizoma Atractylodis Macrocephalae, Poria cocos 6 grams each, Sang Bai, Schisandrae chinensis, Fructus Schisandrae chinensis, Ziyuan Yuan 5 grams each, Radix et Rhizoma Glycyrrhizae Praeparata 3 grams.

Dosage: water decoction, 1 post per day, for 4 weeks

Folding etiology treatment

Allergic cough is a polygenic autosomal dominant disease, the pathogenesis of which is based on the atopic qualities also known as allergic children. A predominantly Th2 response to allergens during the fetal period has been found to be important in avoiding immune rejection between mother and child. The type of immune response to allergens after birth determines whether or not an allergic disease develops: a healthy child is tolerant to allergens and avoids Th2 responses, whereas a child with recurrent allergic symptoms such as allergic cough, asthma, rhinitis, eczema, atopic dermatitis, urticaria, food allergies, drug allergies and other allergic symptoms can be sensitized to allergens and induced to show an over-activated Th2 response.

Secondly, in the Th2 immune response dominant immune response such as after exposure to allergens is more likely to produce high levels of sensitizing antibodies IgE tendency, this is the most important allergic cough susceptibility factors, but also allergic cough recurrence of the root cause of the disease. Some parents may say that their children were never allergic when they were young, but since kindergarten they are prone to coughing and have been identified as having an allergic cough. In fact, usually this Th2 dominated immune atopic body requires a period of sensitization before it can be manifested, and therefore most of the allergic coughs occurring after 1 year of life or in school-age children are gradually manifested, and some even develop in adulthood.

At present, the specific mechanism of the tolerance pathway of allergens in normal children and the tolerance defects in children with allergic cough is unclear. Recent studies have shown that children's immune tolerance to allergens is mediated by the secretion of IL-10 and IFN to regulate the T-cells, inducing a Th1-type immune response. This strengthens the immune defense function of children with allergic cough and improves the children's ability to adapt to the environment.

Treatment of allergic cough

1, the use of jinfuming, five bacteria combined to stimulate immune cells to produce interferon IFN, IL-10 and other cytokines, to reduce IgE, so that the development of the TH1 type of the immune system is complete.

2. Enhance the intestinal barrier function by regulating the ratio of bacterial flora, reduce the release of inflammatory mediators, and inhibit the over-activation of TH2 immune cells in peripheral blood.

The causes of allergic cough and allergic asthma are similar. The causes of allergy are numerous and complex, but they include two main aspects, namely, the constitution of the patient with allergic cough and environmental factors. The patient's constitution includes subjective conditions such as "genetic quality", immune status, mental and psychological status, endocrine and health status, which are important factors in the patient's susceptibility to allergic cough. Environmental factors, including allergens, irritant gases, viral infections, area of residence, conditions of the room, occupational factors, climate, medications, exercise (hyperventilation), food and food additives, dietary habits, social factors and even economic conditions may be even more important causes of the development of allergic cough. The increasing trend in the incidence of allergic cough is also related to the susceptibility of patients due to their allergic constitution and environmental factors. [2]

Oxygen for Health

In 400 A.D., the ancient Greek medical sage Hippocratic said, "The patient's instincts are the patient's doctor, and the patient's best doctor is himself," and he emphasized the power of the human body itself. Modern medical research shows that the human body has an immune system, nervous system and endocrine system based on the body's self-healing system, human life is relying on this natural self-healing power, to be able to survive and reproduce in the ever-changing nature. When the natural self-healing power of the human body declines, there are diseases and aging, so increasing the natural self-healing power of the human body is the key to repairing diseases. Negative ions is through the enhancement of human self-healing power, clinical experiments have proved that negative oxygen ions through the respiratory tract into the human body, can improve the lung capacity. Some people have experimented, in the glass mask inhalation air negative oxygen ions 30min, can make the lungs absorb the amount of oxygen increased by 20%, while the amount of carbon dioxide discharge can be increased by 14. 5%, so the negative oxygen ions have to improve and increase the function of lungs, respiratory, bronchial diseases, etc. has a significant auxiliary therapeutic effect.

By increasing the concentration of negative oxygen ions indoors can effectively remove all types of indoor bacteria and viruses and harmful gases, scientific experiments have proved that: when the concentration of negative ions in the indoor air reaches 20,000 per cubic centimeter or so, the dust particles in the air will be reduced by more than 98%. For lung particles PM2...5 below and finer ultrafine particles excellent effect, airborne bacteria, viruses, dust mites and other sources of disease transmission is almost zero. [3] ?

Diet

Radish and honey drink (treatment of cough --- for a long time)

Ingredients: white radish 5 slices, 3 slices of ginger, 3 jujube, 30 grams of honey.

Preparation: Radish, ginger, jujube with the right amount of water and boil for about 30 minutes, remove the slag, add honey, and then boil. Warm and serve. 1 to 2 times a day.

Functions: Radish is pungent, sweet, cool, has the effect of clearing away heat and generating fluids, cooling the blood and stopping bleeding, resolving phlegm and relieving cough. Its alcohol extract has strong antibacterial effect on gram-positive bacteria. Ginger is commonly used to dispel wind-cold, stop vomiting and lowering of qi, and jujube is often used to harmonize the stomach, nourish blood and harmonize medicines. Honey moistens the dryness and relieves cough, this drink can play the role of the cold to promote the lungs, wind and cough. [1]

Western medicine catalog

1, anti-inflammatory drugs:

① glucocorticoid prednisone budesonide

② anti-leukotriene, zalustat, zileuton

③ inflammatory mediators blocking drugs, cromoglycate, ketotifen

④ inflammatory mediators antagonists, fexofenadine

2, bronchodilators:< /p>

2, bronchodilator: <

① β2 agonists, terbutaline, salmeterol

② xanthines, aminophylline

③ anticholinergics, ipratropium atropine

3, the most commonly used trade names such as:

? Shunrnin, Pramipexole, Aizen, Merrill Lynch, Ciclosporin, Sisumet, Keratan, Schizoprofen, Finagan, Mucosolvan, and so on.

Chinese medicine catalog

Treatment: clearing away heat and removing toxins, strengthening the spleen and drying dampness, tonifying the kidneys and Qi, relieving cough and resolving phlegm, etc.

Pediatric Baibu Cough Syrup, Chuanbei Pei Pa Koa Syrup, Chuanbei Xue Pear Cream, Xiao Qinglong Combination, Syrup for Eliminating Cough and Panting, Pediatric Cough and Panting Pellets, Xiao Qinglong Pellets, Ku Ben Cough and Panting Tablets, etc.

Pediatric allergic cough cough medicine

From the pediatric physiology, cough is a protective reflex, play a role in cleaning the respiratory tract to make it open, as long as the phlegm is discharged, the cough will often be relieved. The reason why cough medicine can stop coughing is because it can act on the cough reflex. However, due to the immaturity of the child's respiratory system, the cough reflex is poor, coupled with the narrow lumen of the bronchial tubes, blood vessels, cilia movement is poor, sputum is not easy to discharge. If you take too much cough medicine such as Cough Bichen, Cough Mephen, Fructus Schisandrae, etc., it is easy to cause a lot of phlegm to be retained in the respiratory tract, resulting in tracheal obstruction, chest tightness, dyspnea, accelerated pulse, and other phenomena, and even secondary bacterial infections.

Treatment of pediatric allergic cough

Allergic cough is a relatively serious type of allergic disease in children, easy to combine with bronchitis, pneumonia and other diseases, eighty percent of the children onset of disease before the age of five years, the treatment of the best in the age of five to seven years, as long as the correct desensitization treatment, most of the children's condition can be controlled, allergic to improve the body, to achieve the purpose of the root cause of the disease.

The treatment of pediatric allergic cough should avoid the abuse of antibiotics and hormones. You can find the allergens by looking for the allergens and desensitize the treatment. In terms of medication, anti-allergy drugs should be used, such as paracetamol, ketotifen, etc., and bronchodilators such as salbutamol and aminophylline can also be used. Parents should be fully aware of pediatric allergic cough, to avoid excessive abuse of cold medicines for babies and cause other adverse reactions. Desensitization

Desensitization therapy is most suitable for allergic rhinitis or allergic asthma caused by inhalation allergens, because inhalation allergens are dispersed everywhere and are difficult to avoid, so the use of desensitization therapy is a kind of important measures to prevent asthma flare-ups. Among them, desensitization therapy is divided into three ways: desensitization injection, sublingual and desensitization patch.

1. Sublingual desensitization

In 2001, the WHO published a white paper stating that sublingual desensitization can completely replace traditional hypodermic therapy. Sublingual desensitization is currently reserved for patients allergic to dust mites and house dust mites. It is safer to use and patients are compliant. The method of administration is to use different maintenance doses depending on age. Drops are taken under the tongue for 1-3 minutes at relatively fixed times of the day and are easy to use. The incremental phase of the dose is divided into 1, 2 and 3. Maintenance doses are divided into No. 4 and No. 5. Generally, No. 4 is used for maintenance for those under 14 years of age and No. 5 for those over 14 years of age.

2. Desensitization patch

Hospitals use "injection desensitization", which is made of allergens into a certain concentration of the leaching solution, and gradually increasing the dose and concentration of the method, repeatedly injecting patients with artificially prepared specific antigens, so as to achieve the gradual induction of the patient to tolerate the antigens without allergic reaction method. "Nano Desensitization Therapy" is based on the principle of "injection desensitization", changing the route of drug delivery and entering the body through percutaneous infiltration. Tio2 (titanium dioxide) nano-microcrystals are added into the packaged dry powder of various allergens with far-infrared washer, and Tio2 (titanium dioxide) nano-microcrystals, catalyzed by light and far-infrared rays, can effectively decompose organic substances in the dry powder of allergens and produce free small-molecule antigens, while Tio2 (titanium dioxide) nano-microcrystals, under photocatalyst, can decompose the hair skin cuticle proteins and enlarge the gap between the skin cuticles, which helps to promote small-molecule antigens and increase the size of the skin cuticle. At the same time, Tio2 (titanium dioxide) nanocrystals can decompose the skin stratum corneum protein under photocatalysis, making the epithelial tissue larger, which is conducive to promoting the continuous penetration of small molecule antigens into the body. The body in the long-term continuous stimulation of these antigens gradually produce immune tolerance, on re-exposure to allergens do not produce a reaction, to achieve the purpose of complete desensitization of the body.

Hazard

It is because of the recurrence of allergic cough and difficult to cure, the cough is very easy to cause other lesions, can spread the tracheal lesions to the neighboring bronchial tubes, combined with the whole respiratory tract infections, so that the condition is aggravated, the emergence of sticky sputum, nasal mucus, asthma, rhinitis and other combined symptoms. In addition, persistent and severe coughing also seriously affects daily rest, affects people's mood, especially easy to consume physical strength, and can cause the destruction of the elastic tissue of the alveolar wall, inducing emphysema and other chronic respiratory diseases, and the infected germs, if not cleared in time, will also cause different degrees of kidney damage. Therefore, the control of allergic cough is focused on prevention, and when it becomes serious and then treated, it is much more difficult.

In the prevention and treatment of allergic cough, it is common for patients to report that a large number of antibiotics to eliminate respiratory infections may be better initially, but more often than not, resistance is also easy to develop, and the therapeutic effect is not obvious, and the treatment of bronchodilators can relieve coughing episodes, which is also a basic condition required for the diagnosis of allergic cough. In clinical practice, cough variant asthma is often misdiagnosed as bronchitis and recurrent respiratory infections. In some typical cases, due to unclear diagnosis, antibiotics have been used to treat bacterial infections, and because of the unsatisfactory treatment, the application of antibiotics has been continuously upgraded, which affects the physical and mental health of the patients and imposes an economic burden on the families. Therefore, the search for a safe and thorough treatment for the eradication of allergic cough has become an urgent need for many patients!

Drawbacks of traditional treatment

In the issue of combating allergic cough, it is common for patients to reflect that the use of a large number of antibiotics to eliminate respiratory infections may initially be better, but with more use of antibiotics is also prone to drug resistance, and its therapeutic effect is not obvious, and the treatment of bronchodilators can lead to the relief of coughing episodes, which is also the basic conditions required to diagnose anaphylactic cough. In clinical practice, cough variant asthma is often misdiagnosed as bronchitis and recurrent respiratory infections. In some typical cases, due to unclear diagnosis, antibiotics have been used to treat bacterial infections, and because of unsatisfactory treatment, the application of antibiotics has been continuously escalated, which affects the physical and mental health of the patients and imposes an economic burden on their families. Therefore, the search for a safe and complete cure for allergic cough has become an urgent need for many patients!

Prevention

1, when the outdoor ambient temperature drops to 25 to 26 ℃, dust mites, mold and other allergens are more, at this time should pay attention to avoid allergens;

2, in the alternation of the seasons, sudden changes in temperature, parents should try to do a good job for the children to prevent the cold warmth of the preparations, to avoid catching a cold, a cold;

3, to avoid eating food that can cause allergic symptoms, such as Seafood, etc.

4, avoid three cold: cold drinks, cold wind, air conditioning is too cold;

5, avoid three: laughing, shouting, crying;

6, appropriate exercise. Children should avoid strenuous exercise in a dry and cold environment. Such as the ban on ice and snow in sustained strenuous exercise. And warm environment, high humidity or intermittent exercise should be encouraged. When engaging in sports, in order not to feel chest tightness, shortness of breath, physical discomfort as a principle, there are symptoms should stop exercise, strengthen the rest.