Pain in liver area is a common symptom of advanced stage of liver cancer, and the incidence rate is more than 50%. Pain in liver area is usually located in the right rib or under the raphe, and the nature of pain is mainly intermittent or persistent hidden pain, or dull pain or stabbing pain can also occur. For some time before the pain, patients may feel discomfort in the right upper abdomen. The reason for the pain is mainly due to the rapid growth of the tumor, compression of the hepatic peritoneum, resulting in tugging pain, but also due to the necrotic material of the tumor to stimulate the hepatic peritoneum.