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Cholinergic urticaria symptoms
Cholinergic urticaria is a kind of rash that people often say. When you are heated, nervous, eating hot food or drink, or after exercise, your body temperature rises slightly. The heated blood flow stimulates the brain's thermoregulatory center, excites cholinergic nerves and releases acetylcholine. If you are allergic to this chemical, you may have an allergic reaction.

This allergic reaction has no rash, only acupuncture and severe itching, and red air masses of about 2 mm can also appear on the skin near the trunk and limbs (except armpits, palms and soles). This kind of wind mass comes quickly and leaves no trace. Ordinary people may have mild cholinergic urticaria in adolescence. Generally, after stopping exercise or calming down, the symptoms can subside, so it is not easy to attract attention. The whole process can last for months to years, and those who have frequent attacks should go to dermatology for treatment in time. After treatment with antihistamines and anticholinergic drugs, the condition can be alleviated or alleviated.

Mental stress, body heat or exercise often induce skin lesions. The biggest clinical feature of the disease is that the damage of wheal is quite small, about 1 ~ 3 mm, and the surrounding area is flushed and extremely itchy, often accompanied by symptoms such as headache, dizziness, salivation and sweating. Sometimes you can see a satellite-like wind mass. 1: 5000 acetylcholine intradermal test can be positive, that is, there is strong erythema. This type of palmoplantar is usually not involved, and the disease may recur for months or years.

Six suggestions for patients with cholinergic urticaria.

1, pay attention to diet and avoid irritation. The incidence of urticaria has a certain relationship with diet, and some foods may be the cause. For example, fish, shrimp, seafood, canned food containing artificial additives such as artificial pigments, preservatives and yeast, pickled food and beverages can all induce urticaria. In addition, irritating foods such as too hot and sour will also reduce the digestive function of the gastrointestinal tract, making food residues stay in the intestine for too long, thus producing peptones and peptides, increasing the probability of human allergies.

2. Pay attention to hygiene and avoid bad stimulation. People with a history of urticaria should pay attention to keeping indoor and outdoor clean, and keep fewer pets such as cats and dogs at home. Avoid inhaling pollen, dust, etc. Avoid wind, cold, heat, dampness, dryness, fire and insect poison. Adapt the law of life to the changes in the external environment. Drinking, heating, emotional excitement, exertion, etc. It will aggravate skin vasodilation and stimulate or aggravate urticaria. Rubber gloves, hair dyes, soaps and detergents, chemical fibers and wool clothes may be bad stimuli for patients with allergies or urticaria and should be avoided. People suffering from cold urticaria should not go to the beach or take a cold bath. Keep warm in winter. Cholinergic urticaria should keep the body cool and avoid sweating. According to related research, the positive rate of IgE in blood and skin test of smokers is significantly higher than that of non-smokers, and the allergic phenomena caused by passive smokers such as their children are also relatively increasing. Therefore, patients with urticaria should quit smoking.

3, pay attention to allergies caused by drug factors. Clinically, some drugs can cause urticaria, such as penicillin, tetracycline, chloramphenicol, streptomycin, sulfonamides, polymyxin and other antibiotics, analgin, aspirin and other antipyretic and analgesic drugs. Some Chinese patent medicines, such as Ganmaoqing and Niuhuang Jiedu tablets, can also cause allergies and urticaria. When you are taking a variety of drugs and suspect that urticaria is caused by one of them, the simplest and most effective way is to stop taking them in time.

4. Actively treat the original disease. Urticaria is not only an independent disease, but also a skin manifestation of some diseases. There are many diseases that can cause urticaria, such as infectious diseases: parasitic infections such as intestinal roundworm and pinworm; Bacterial infection, such as dental caries, alveolar abscess, tonsillitis, otitis media, sinusitis, etc. Hepatitis B virus infection; Fungal infections such as tinea manus and pedis. In addition, diabetes, hyperthyroidism, menstrual disorders and even potential tumors in the body may cause urticaria. Therefore, effective diagnosis and treatment of the primary disease will help to eliminate urticaria.

5. Keep a healthy mind and improve your body resistance. The attack and aggravation of chronic urticaria are related to people's emotional or psychological stress. Traditional Chinese medicine has the theory of "indifferent to nothingness, safe from illness" in the prevention and treatment of diseases. It is believed that keeping a pure heart and lacking desires can make the human body run harmoniously with blood vessels unobstructed and healthy qi abundant. Over time, urticaria will naturally disappear invisibly.

6, anti-allergic probiotics. Xinminkang anti-allergic probiotics can participate in IgE-mediated immune allergic reaction. It is determined that human dendritic cells can produce organic acids, free fatty acids, hydrogen peroxide and bacteriocin after co-culture with anti-allergic probiotics, thus inhibiting the growth of other harmful bacteria. After "biological hypoxia", aerobic pathogens are greatly reduced. Probiotics can colonize mucosa, skin and other surfaces or cells, forming a biological barrier, which can hinder the colonization of pathogenic microorganisms and play a role in occupying space, grabbing nutrition and mutual benefit. The anti-allergic probiotic Xinmin Kang can also affect the nonspecific immune function of the body, thus naturally killing the activity of NK cells, enhancing the secretion of immunoglobulin IgA, and improving the skin appearance or cell barrier function. Can effectively treat various types of allergies, including urticaria, allergic rhinitis, conjunctivitis, atopic dermatitis, allergic asthma, food, pollen and other allergic symptoms.

7. Cholinergic urticaria: In addition to routine antihistamines, atropine, propofol and reserpine are often added, and the effect is satisfactory.