1, Hua decree poisoning (double coumarin) poisoning. Such as: rodenticide ketone, rat enemy

①. Symptoms: anticoagulant rodenticides, the most common, leading to chronic poisoning. Bleeding is the biggest feature, but there is often a 2-5 day incubation period before the appearance of this symptom, mainly manifested as extreme depression, elevated body temperature, loss of appetite, anemia, weakness, internal and external hemorrhage, external hemorrhage manifested as nosebleeds, vomiting blood, hematuria, bloody stools or black feces. Internal hemorrhage occurs in the chest and abdominal cavity due to respiratory distress; occurs in the brain, spine, neurological symptoms; occurs in the joints, claudication, but also can be seen in the joint cavity hemorrhage, subcutaneous and submucosal hemorrhage, subcutaneous hemorrhage can cause dermatitis and skin necrosis, severe bleeding from the nostrils, the rectum, and other natural orifices, the poisoning of a large number of people, can be in the stomach, the appearance of typical hemorrhagic symptoms and death. Chronic poisoning can be manifested as anemia, edema, heart failure, spasm and paralysis can occur in the final stage. Jaundice can occur when the disease is very long.

②. Treatment: early emesis, blood replenishment for acute poisoning, vitamin K supplementation; for subacute poisoning, subcutaneous injection of vitamin K until the clotting time is normalized, and then change to oral vitamin K1, 15-30 mg, twice a day for 4-6 days. Severe cases require transfusion of fresh whole blood 10-20 ml/kg body weight, the first half should be fast, the second half 20 drops/minute. Warfarin and rat poisonings sometimes take up to a month, and barbiturate sedation or mild anesthesia should be applied to assist treatment. Note: insurance, as long as the suspicion of such poisoning, should be immediately oral vitamin k1.

(2), organophosphorus compounds pesticide poisoning. Such as: trichlorfon, Rogaine, dichlorvos, trisulfoton, malathion, etc.

①. Symptoms: initial excitement, muscle spasms, light tremors, heavy convulsions, muscle clonus of the limbs, the sick dog frequently stepped, lying down horizontally to do swimming movements. The pupils are narrowed and become linear in severe cases. There is a lot of salivation, tearing, abdominal pain, loud bowel sounds, constant diarrhea, and even fecal incontinence. In the late stage of severe disease, the bowel sounds are weakened or even disappear. Sweat dripping all over the body, especially severe on the chest, perineum and around the scrotum. Body temperature rises, respiration is obviously difficult, heartbeat is rapid, pulse is weak, conjunctiva is cyanotic, and finally death is caused by asphyxia. When the amount of poisoning is relatively light, the blood may be drawn after 12-24 hours.

②. TREATMENT: atropine sulfate is given slowly intravenously at a dosage of 0.05 mg/kg body weight. After an interval of 6 hours, subcutaneous or intramuscular injection of atropine sulfate at a dosage of 0.15 mg/kg body weight. The drug may be discontinued when the dog's mouth is dry, pupils are dilated, breathing is steady, and the heart rate is rapid. In severe cases, it is best to use atropine in conjunction with iododefodine and chlorodefodine. Iodophosphatidine (Pym) and chlorophosphatidine (Chlorophos) are cholinesterase revitalizers, but have poor efficacy in the pesticide poisonings mentioned above and must be used in conjunction with atropine. The dosage of iodophosphamide is 20 mg/kg body weight per dose, intravenously, and repeated over 12 hours if necessary. Chlorophosphamide dosage is 20 mg/kg body weight per dose. Difluprednate crosses the blood-brain barrier and acts like atropine at a dosage of 15-30 mg/kg body weight per dose. However, individual dogs are allergic to iodophosphatidine and chlorophosphatidine and care should be taken. In addition, benadryl can also be, 1-4mg/kg, oral, 3 times a day, mainly for the occurrence of muscle spasm, tremor cases.

3, organic fluoride poisoning

①. Symptoms: dogs drink water contaminated by organic fluorine compounds, or eat rats poisoned by fluoroacetamide, causing central nervous system excitation. Restlessness, vomiting, dyspnea, arrhythmia, increased defecation, running wildly and barking, paroxysmal or tonic muscle spasms, foaming at the mouth, and finally showing coma and panting, and dying of respiratory depression and cardiac failure during convulsions.

②. Treatment: acetamide (desflurane) can prolong the incubation period of poisoning and reduce the symptoms of the onset. The dosage is 0.1 mg/kg body weight each time. The first dosage is half of the whole day's amount, and the remaining half is divided into 4 parts and injected every 2 hours. Always administer early and in sufficient doses. If used in conjunction with chlorpromazine and barbiturate tranquilizers, it may reduce central nervous system excitability. It may be combined with emesis and gastric lavage, and the sick dog may be allowed to eat raw egg whites to protect the mucosa of the digestive tract. Intravenous calcium gluconate 5-10 ml is also beneficial.

(4), amphetamine-type rodenticide poisoning

Symptoms: accidental ingestion of this white, odorless crystalline powder, causing increased pulmonary capillary permeability, plasma into the lung tissue in large quantities, resulting in pulmonary edema. Sick dogs vomiting, foaming at the mouth, followed by diarrhea, coughing, dyspnea, depression, cyanosis of the mucous membranes, nostrils out of the foamy blood-colored mucus. Due to respiratory distress dogs mostly take a sitting position, weak pulse rate, low temperature, 12 hours later, may die due to hypoxia. There is no specific antidote for this drug, can be used to induce vomiting, gastric lavage, diaphoresis, rehydration, diuresis.

(5), chlorinated hydrocarbon pesticide poisoning. Such as: dichlorvos, six six six, TDE, chlordane endosulfan and other pesticides

①. Symptoms: extreme excitement, mania, head and neck first tremor, and then spread to the whole body, salivation, do not eat or eat less, diarrhea. In severe cases, the mucous membrane is red, fidgety, paroxysmal generalized spasm occurs from time to time, and there is white foam at the corner of the mouth. Auditory, tactile manifestations of allergy, if the poison is taken by mouth, vomiting, elevated body temperature, once on the ground, the limbs paddle, was horny, is the point of difference with other poisonings.

②. Treatment: available cleaning method and gastric lavage, followed by saline laxatives for diarrhea. The administration of tranquilizers can symptomatically treat the dog's over-excitement. As the dog is dehydrated and does not eat, intravenous fluids should be given. Those poisoned via the skin should be washed locally with plenty of warm soapy water, and those poisoned via the mouth should be instilled with activated charcoal and artificial salt. Vomiting is not allowed! It can lead to myoclonic spasms. To control over-excitation, diazepam and pentobarbital are commonly used, but in the absence of convulsions, pentobarbital must not be applied, only diazepam.

(6), zinc phosphide rodenticide poisoning, gray powdery commonly used rodenticides

①. Symptoms: symptoms usually appear within 15 minutes to 4 hours, causing abdominal pain, non-feeding, vomiting, coma and drowsiness, suffocation, diarrhea, blood in stool. Vomit contains black blood, phosphorescence visible in the dark, and an acetylene odor. Dyskinesia, barking, elevated body temperature and acidosis, and finally struggling limbs and sensory hypersensitivity until muscle spasms and death due to lack of oxygen.

②. Treatment: 0.2-0.5% copper sulfate solution 10-30 ml can be instilled to induce vomiting. Gastric lavage can be 0.02% potassium permanganate solution, followed by 15 grams of sodium sulfate diarrhea. Intravenous hypertonic glucose solution is used to protect the liver. Early can also apply 5% sodium bicarbonate gastric lavage, oral 5% sodium bicarbonate to increase the gastric pH value, to prevent the release of zinc phosphide. 24 hours of fasting to reduce gastric acid secretion.

(7), carbamate poisoning. Such as: carbofuran, methomyl, carbaryl, furadan, co-killer, mix-killer, etc.

①. Symptoms: similar to organophosphorus poisoning, but its duration is shorter;

②. Treatment: and organophosphorus treatment is basically the same, should be injected as soon as possible atropine sulfate, if necessary, can be repeated.

(8) Arsenide (i.e. arsenic) poisoning

①. Symptoms: severe abdominal pain, muscle tremors, salivation, vomiting, hobbling, diarrhea, thirst, hind limb paralysis, swelling of the oral mucosa, the gums become dark black, and in severe cases, the oral mucosa can be seen to be ulcerated and detached. Individual dogs are in a state of excitement, convulsions, sweating, coldness at the end of the body, and paralysis of some parts of the muscles. Male dogs can be seen pubic colonization, destruction of cells and severe pathogenicity. In chronic cases, encapsulated worms are formed in the brain, muscles, retina, lungs, liver and kidneys. Toxoplasma gondii in addition to infection through the digestive tract, but also through the nose, eyes, respiratory tract and skin, embryos and other ways to invade carnivores and omnivores; sick dogs and carriers of meat, viscera, blood, exudate (such as ascites), feces, milk and aborted fetuses, placenta and other things with toxoplasma gondii; a variety of insects can also spread this disease.

(1) Symptoms: generally no symptoms; severe infection with fever, cough, anorexia, weakness, eye and nasal discharge, and even hemorrhagic dysentery, vomiting, paralysis, abortion or preterm delivery of pregnant bitches, very similar to the symptoms of distemper and infectious hepatitis;

(2) Diagnosis: take the tissues, body fluids for smears, slides and staining to find the Toxoplasma gondii, or 10-fold diluted diseased material, intraperitoneal inoculation of mice. Serological examination of specific antibodies can confirm the diagnosis;

(3) prevention and treatment: the effect of treatment with sulfonamide 6 methoxypyrimidine is good, but to be used at the beginning of the disease; the late stage of the disease, although the symptoms can be made to disappear, but can not inhibit Toxoplasma toxoplasmosis into an encysted type, thus becoming a carrier. Prevention is by separating cats and dogs or limiting exposure, and controlling wildlife, especially rodents.

Don't know the specifics of your dog, the disease of poisoning I have written, to see if it can help your dog, I hope it will soon recover!