2 English reference Magnolia Officialis [21century bilingual dictionary of science and technology]
Cortex magnoliae officinalis [landau Chinese-English dictionary]
Magnolia hypoleuca [Landau Chinese-English Dictionary]
Magnolia bark [Xiangya Medical Dictionary]
Magnoliae cortex [Xiangya medical dictionary]
Magnoliae officinalis,cortex [Xiangya medical dictionary]
Officinal magnolia bark [Xiangya Medical Dictionary]
Cortex Magnoliae Officinalis [Chinese Medicine Terminology Examination Committee. Chinese Medicine Terminology (2004)]
Officinal magnolia bark [Chinese Medicine Terminology Examination Committee. Chinese Medicine Terminology (2004)]
3 Overview of Magnolia Officinalis
Magnolia officinalis is the name of traditional Chinese medicine, and it is published in Shennong Herbal Classic. Is the dried dry bark, root bark and branch bark of Magnolia officinalis Rehd. et Wils. or magnolia officinalis Rehd. et wils. var. Biloba Rehd. et wils. of Magnoliaceae [1].
Pharmacopoeia of the People's Republic of China (20 10 edition) records the pharmacopoeia standard of this Chinese medicine.
4 Latin name Cortex Magnoliae Officinalis (Latin) (Terminology of Traditional Chinese Medicine (2004))
5 English name officinal magnolia bark (Terminology of Traditional Chinese Medicine (2004))
Twolobed Officinal Magnolia Bark
6 Magnolia officinalis's alias is heavy skin, red park and oil park.
Thick skin, heavy skin, Chuanpu, Magnolia officinalis [2].
7. The sources of Magnolia officinalis Rehd. et Wils. of Magnoliaceae or Magnolia Officinalis Rehd. et wils. var. Biloba Rehd. et wils. are dried dry bark, root bark and branch bark [1].
Magnolia officinalis is the bark or root bark of Magnolia officinalis Rehd．et Wils. or Magnolia officinalis M. Officinalis Rehd. Etwils. var. Biloba (Rehd. Etwils.) Cheng of Magnoliaceae [2].
Magnolia officinalis is the skin of magnolia officinalis Rehd. etwils.var.bilobarehd.etwils. of Magnoliaceae. Cortex Magnoliae M.officinalis is used as medicine.
8 Origin Magnolia Officinalis mainly produced in Sichuan, Hubei, Zhejiang, Guizhou and Hunan [2].
Deciduous tree in original plant form with light brown bark. Leaves alternate, leathery, narrowly obovate,15 ~ 30cm long and 8 ~17cm wide, with a notch at the top or 2 obtuse shallow lobes, wedge-shaped base, lateral veins15 ~ 25 pairs, grayish green below, and hairy when young; Petiole has white hairs. The flowers are white and fragrant; Tepals 9 ~12; Stamens and carpels are numerous. Aggregate fruit is cylindrical and oval, with a length of11~16cm; Wood, with a short point. The flowering period is from April to May, and the fruiting period is from September to1October.
I like to be born on the fertile sandy loam which is cool, moist and acidic.
10 origin Magnolia officinalis is produced in Fujian, Zhejiang, Anhui, Jiangxi and Hunan.
1 1 harvesting and primary processing: peel off the root bark and branch bark in the shade from April to June; After the dried skin is slightly boiled in boiling water, it is piled in a damp place, and when the inner surface turns purple or brown, it is steamed to be soft, taken out, rolled into a tube and dried.
12 pharmacognosy: the dry skin is in the shape of double drum and single drum, with a thickness of 2 ~ 8 mm; The outer surface is brown-gray, rough, sometimes scaly, easy to peel off, with many lenticels, and the rough skin is yellow-brown after scraping; The inner surface is purple-brown, marked with oil marks; Hard, not easy to break; The outer side of the section is grayish brown, the inner layer is purplish brown or brown, oily, and some can see most bright small crystals. The branch bark and root bark are single tube-shaped, and some root barks are curved. It is fragrant, spicy and slightly bitter.
13 the taste of Magnolia officinalis is bitter, pungent and warm; Into the spleen, stomach, large intestine meridian [2].
14 Efficacy of Magnolia Officinalis and Indication Magnolia Officinalis has the efficacy of eliminating dampness, eliminating phlegm, and removing fullness due to lower qi, and can be used for treating damp stagnation, abdominal distension, constipation, phlegm retention, asthma and cough.
Magnolia Officinalis has the effects of warming the middle warmer and lowering the qi, eliminating dampness and eliminating phlegm, and treating abdominal distension and pain, vomiting, diarrhea, food retention, phlegm and cough and asthma [2].
Magnolia officinalis is a commonly used medicine for regulating qi in ophthalmology, which has the effects of promoting qi circulation, eliminating dampness, lowering adverse qi and relieving asthma. It is used for white eye swelling and redness, nodule uplift, cloud shifting, and colored vision caused by unfavorable qi movement and stagnant water and dampness. It is often combined with Coicis Semen, Faxia and Talc, such as Sanren Decoction.
15 Usage and dosage of Magnolia Officinalis: 3 ~ 9g [2].
16 Magnolia officinalis contains magnolol and honokiol.
Both bark of Magnolia officinalis and Magnolia officinalis contain magnolol and Honokiol. Magnolia officinalis also contains magnolol, magnololignans A ~ I, terpineol dimethyl ether, magnoliacurine and so on. It also contains volatile oil, including eucalyptol and syringone [2].
Magnolia officinalis has inhibitory effects on central nervous system and isolated toad heart [2].
Magnolia officinalis decoction can excite rabbit intestinal tract and bronchial smooth muscle [2].
The water extract of Magnolia Officinalis can resist inflammation [2].
Magnolia officinalis has inhibitory effect on Staphylococcus aureus, Escherichia coli and some skin fungi, and has the effect of expelling ascaris suum [2].
Alkaloids have the effect of relaxing muscles like curare and lowering blood pressure [2].
The alcohol extract of Magnolia officinalis and magnolol have inhibitory effects on experimental gastric ulcer [2].
17 Pharmacopoeia Standard of Magnolia Officinalis 17. 1 Name of Magnolia Officinalis
Houpo
MAGNOLIAE OFFICMALIS CORTEX
17.2 source this product is the dried dry bark, root bark and branch bark of Magnolia officinalis Rehd.et Wils. or magnolia officinalis Rehd. et wils. var. bilobarehd. et wils. of Magnoliaceae. Peeling from April to June, and directly drying the root bark and branch bark in the shade; After the dried skin is slightly boiled in boiling water, it is piled in a damp place, and when the inner surface turns purple or brown, it is steamed to be soft, taken out, rolled into a tube and dried.
17.3 dry skin? It is drum-shaped or double-drum-shaped, with a length of 30 ~ 35 cm and a thickness of 0.2 ~ 0.7 cm, which is commonly called "simplicity"; One end of the dry leather near the root is spread out like a bell mouth, with a length of13 ~ 25 cm and a thickness of 0.3 ~ 0.8 cm, which is commonly called "boot barrel park". The outer surface is gray-brown or gray-brown, rough, sometimes scaly, easy to peel off, with obvious oval lenticels and longitudinal wrinkles, and the rough skin is yellow-brown. The inner surface is purple-brown or dark purple-brown, smooth, with fine longitudinal stripes, and marked with oil marks. Hard, not easy to break, granular in cross section, gray-brown in outer layer, purple-brown or brown in inner layer, oily, and some small bright stars can be seen. It is fragrant, spicy and slightly bitter.
Root bark (root bark) Single-tube or irregular block; Some bend like chicken intestines, which is called "chicken intestines are simple". Hard, easy to break, fibrous section.
Branch skin (branch park)? It is a single tube, with a length of10 ~ 20 cm and a thickness of 0.1~ 0.2 cm. Brittle, easy to break, and fibrous in section.
17.4 Identification (1) Cross section of this product: cork layer is 10 cells; Some can see the cortex. There are stone cell bands outside the cortex, and most oil cells and stone cell groups are scattered inside. Phloem ray width1~ 3 rows of cells; Many fibers are in bundles; There are also oil cells scattered.
Powder brown. There are many fibers, the diameter is15 ~ 32 μ m, the wall is very thick, some are wavy or serrated on one side, lignified, and the holes and grooves are not obvious. The stone cells are square, oval, oval or irregularly branched, with a diameter of11~ 65μ m, and sometimes striations can be seen. Oil cells are oval or quasi-round, with a diameter of 50 ~ 85 μ m and yellow-brown oil.
(2) Take 0.5g of this product powder, add 5ml of methanol, tightly plug it, shake it for 30min, filter it, and take the filtrate as the test solution. In addition, magnolol reference substance and honokiol reference substance were taken, and methanol was added to prepare a mixed solution containing 1m 1 mg each, which was used as the reference solution. According to the test of thin-layer chromatography (Appendix VI B), absorb 5μl of each of the above two solutions, respectively spot them on the same silica gel G thin-layer plate, use toluene-methanol (17:1) as the developing agent, unfold, take out, air dry, spray with1%vanillin sulfuric acid solution, spray with/kloc-0. In the chromatogram of the test sample, spots with the same color appear in the position corresponding to the chromatogram of the control sample.
17.5 inspection 17.5. 1 moisture shall not exceed15.0% (appendix ⅸ h second method).
17.5.2 the total ash content shall not exceed 7.0% (appendix ⅸ k).
17.5.3 the acid-insoluble ash content shall not exceed 3.0% (appendix ⅸ k).
The content of 17.6 was determined by high performance liquid chromatography (Appendix VID).
17.6. 1 chromatographic conditions and system applicability test with octadecylsilane bonded silica gel as filler; Methanol-water (78: 22) was used as mobile phase; The detection wavelength is 294nm. The theoretical plate number should be not less than 3800 calculated by magnolol peak.
17.6.2 preparation of reference solution take appropriate amount of magnolol reference substance and honokiol reference substance, accurately weigh them, and add methanol to prepare solutions containing 40μg of honokiol and 24μg of honokiol per 1ml, respectively.
17.6.3 Preparation of test solution Take about 0.2g of this product powder (passed through the No.3 sieve), weigh it accurately, put it in a conical flask with a stopper, add 25ml of methanol accurately, shake it evenly, plug it tightly, soak it for 24 hours, filter it, accurately measure 5ml of continuous filtrate, put it in a 25ml volumetric flask, add methanol to the scale and shake it evenly.
17.6.4 determination method, respectively, accurately absorb 4μl of the above two reference solutions and 3 ~ 5 μ l of the test solution, inject them into a liquid chromatograph, and determine to obtain the product.
Calculated as a dry product, the total amount of magnolol (C 18H 18O2) and honokiol (C 18H 18O2) in this product shall not be less than 2.0%.
17.7 pieces of magnolia officinalis 17.7. 1 processing 17.7. 1. 1 magnolia officinalis scraped off the rough skin, washed, moistened, shredded and dried.
This product is in the shape of curved silk strip or single or double drum. The outer surface is grayish brown, and sometimes oval lenticels or longitudinal wrinkles can be seen. The inner surface is purple-brown or dark purple-brown, smooth, with fine longitudinal stripes, and marked with oil marks. The cut surface is granular and oily, and some small bright stars can be seen. It is fragrant, spicy and slightly bitter.
The total ash content is the same as that of medicinal materials, and shall not exceed 5.0%.
17.7.1.1.1The content is the same as that of the medicinal materials.
17.7.10.2 ginger magnolia officinalis, take magnolia officinalis shreds, and fry them according to the ginger juice frying method (appendix ⅡD).
This product is shaped like magnolia silk, with grayish brown surface and occasional focal spots. Slightly ginger and spicy.
The total ash content is the same as that of medicinal materials, and shall not exceed 5.0%.
17.7.1.2.1content determination is the same as that of the traditional Chinese medicine, containing magnolol (C 18H 18O2) and magnolol (C 18H 18O2).
17.7.2 Sexual taste and bitter, pungent and warm meridian tropism. Enter spleen, stomach, lung and large intestine meridian. Function and indication
Eliminate dampness and phlegm, and remove fullness with lower qi. It can be used for damp-stagnation injury, epigastric vomiting and diarrhea, food stagnation and qi stagnation, abdominal distension and constipation, phlegm retention, asthma and cough.
17.7.3 Usage and dosage 3 ~10g.
17.7.4 Store in a ventilated and dry place.
17.8 Source