Category fruit category

Evodia rutaecarpa with different names (Herbs and Plants Convenient Prescription) and Zuo Li (Records of Ji Wu in Nanning).

The source is immature fruit of rutaceae plant Evodia rutaecarpa.

Plant morphology Evodia rutaecarpa, also known as: chili pepper, smelly chili pepper tree, qi chili pepper, Qu Yaozi, tea spicy.

Evergreen shrubs or small trees, 2.5 ~ 5 meters high. Young branches, leaf axes and petioles are densely yellow-brown villous. Singular pinnate compound leaves, opposite; 2 ~ 4 pairs of leaflets, oval to oval, 5 ~15cm long, 2.5 ~ 6cm wide, short and acute at the apex, with little tapering, wedge-shaped to round at the base, entire, with few inconspicuous round serrations, densely covered with yellowish villous on both sides, thick paper or paper, with oil spots. Flowers unisexual, dioecious, cymes, occasionally conical, terminal; Floral axis has 2 bracts at the base, and the upper bracts are scaly; Flowers are small, yellowish white. Sepals 5, broadly ovoid, with yellowish pubescence on the outside; Petals 5, oblong, densely white villous inside; Male flowers have 5 stamens, longer than petals, anthers are basifixed, oval, filaments are hairy, degenerated ovary is slightly triangular, hairy, and the apex is 4 ~ 5-lobed; The female flower is large, with 5 staminodes, scales, and 5 carpels. The style is thick and short, the stigma is head-shaped, the capsule is oblate, about 3 mm long, about 6 mm in diameter, purple when ripe, with glandular spots on the surface, and each carpel has seeds 1 piece, which is oval, black and shiny. The flowering period is from June to August. The fruiting period is 9 ~10 month.

Wild in mountains, roadsides or sparse forests. Distributed in Changkang River Basin, South China and Shaanxi.

The roots (roots of Evodia rutaecarpa) and leaves (leaves of Evodia rutaecarpa) of this plant are also used for medicine, and each of them is detailed.

Collected in August ~10 month, harvested when the fruit is dark green and the carpel has not been separated. Take it off and dry it in the sun to remove impurities. In case of rain, dry it with a slight fire kang.

The dried fruit of medicinal materials is pentagonal oblate, with a diameter of 2 ~ 5 mm and a height of about1.5 ~ 3 mm. The surface is green or greenish brown, rough, with fine wrinkles and mane eyes (oil chamber); The top is flat, there are pits and five cracks in the middle, sometimes there are protruding stigmas in the center of the cracks, and there are calyxes and fruit stalks at the base. The fruit stalks are square and round, 3 mm long, brown and green, and densely hairy. In transverse section, the ovary has 5 cells, and each cell has pale yellow seeds1~ 2. The seeds are oily, hard and fragile. Strong aroma, bitter and slightly spicy taste. It is better to be green and full.

Location: Guizhou, Guangxi, Hunan, Yunnan, Shaanxi, Zhejiang, Sichuan and other places.

In addition to the above varieties, there are immature fruits of Shi Hu and Evodia pubescens, which are also used equally.

The volatile oil contained in the fruit of Evodia rutaecarpa is evodiamine, basilene, evolactone, evolactone alcohol, etc. Also contains evocative acid. It also contains alkaloids: evodiamine, rutaecarpine, evodiamine, hydroxyevodiamine and evodiamine. Evodiamine is converted into isoevodiamine after being treated with hydrochloric acid and ethanol. It also contains two neutral nitrogen-free substances: evodiamine and evodiamine. It also contains evodiamine.

Shi Hu fruit contains evodiamine, evodiamine, rutaecarpine and hydroxyevodiamine. It also contains unsaturated ketones, temporarily called Shi Hu A, volatile oil, anthocyanins and steroids.

Pharmacological action ① the effect of expelling octopus

The ethanol extract of Evodia rutaecarpa has a significant effect on ascaris suum in vitro. It is also effective for earthworms and leeches.

② Antibacterial effect

Evodia rutaecarpa decoction (100%) has a strong inhibitory effect on Vibrio cholerae (agar trenching plate method). 10% aqueous solution has inhibitory effect on dermatophytes floccosum in vitro; 1:3 aqueous extract has different degrees of inhibition on 1 1 species of dermatophytes such as Cyclobalanopsis Oduanensis.

③ Central function

A large number of Evodia rutaecarpa have an exciting effect on the central nervous system, and can cause visual impairment and illusion. The ethanol extract of Evodia rutaecarpa produced in Japan has analgesic effect, which was proved by rabbit dental pulp electrokinetic method. 10% ethanol extract has analgesic effect by intravenous injection of 0.1~ 0.5 ml/kg. The analgesic effect of intravenous injection of 0.2 ml is almost the same as that of antipyrine or aminopyrine (1%2 ml each). But in cold, it is stronger than these two drugs. 0. 1% isoevodiamine hydrochloride 0.1~ 0.5 ml/kg, which also has analgesic effect on rabbits; 1~ 2ml/kg can slightly increase the body temperature of rabbits. 0.5 ~ 2.0 ml of 10% ethanol extract of Evodia can also raise the body temperature of rabbits. An alkaloid was proposed from another EvodiaxanthoxyloidesF.Muell, a plant of Evodia rutaecarpa. Its hydrochloride has sedative and hypnotic effects on mice, but it can reduce the body temperature of rats, and it can also resist the convulsion caused by camphor and so on.

④ Other functions

0.5 ~ 10% ethanol extract of Evodia, injected into rabbits, had a short and slight increase in blood pressure, slightly excited breathing and increased carotid blood flow. 0. 1% isoevodiamine hydrochloride (0.2 ~ 0.5 ml/kg) was injected intravenously, but the blood pressure of rabbits did not change significantly, and their breathing increased slightly. The effect of 0.02 ~ 0.1%on isolated frog heart is not obvious, and the perfusion of frog lower limbs is generally not obvious, which expands first and then contracts; For the isolated rabbit intestine, there was a brief excitement at first and then paralysis; It has an exciting effect on rabbit palace in vitro. Evoxine has low toxicity, and its lethal dose to mice is 705 mg/kg by subcutaneous injection and 135 mg/kg by intravenous injection. The components of Evodia rutaecarpa, such as evodiamine, evodiamine, rutaecarpine, have similar effects of analgesia, raising body temperature and slightly affecting respiration and blood pressure. Rutine, the decomposition product of rutaecarpine, has a strong uterine contraction effect. Evodiamine has anti-columbiask effect in mice.

Alkaloids obtained from E.xanthoxyJoides are similar to artemisinine, which can enhance the action of adrenaline, improve the excitability of spinal cord reflex, relax the smooth muscle of small intestine and improve the tension of striated muscle, and are similar to ephedrine in some aspects.

Processing and roasting Evodia rutaecarpa: decoct Glycyrrhiza uralensis Fisch., remove residues to get soup, add clean Evodia rutaecarpa, soak until the soup is completely absorbed, and bake it with low fire. (Every Evodia rutaecarpa 100 kg, 6 kg of licorice is used)

① Herbal Tongxuan: "Evodia rutaecarpa, soak the strong juice in salty soup, and bake the water."

2 "Materia Medica Seeking Truth": "Evodia rutaecarpa Chen Zheliang, soak the bitter juice for use. "Stir-fry Coptis chinensis with water to stop vomiting, saline to treat hernia and vinegar to treat blood."

Sex tastes bitter, warm and poisonous.

① Classic: "pungent and warm."

(2) Bielu: "Big fever, little poison."

③ The Theory of Medicinal Properties: "Bitter and pungent in taste, hot and toxic."

Meridian tropism enters the liver and stomach meridians.

① Herbal Decoction: "Entering the meridians of Taiyin, Shaoyin and Jueyin."

② Explanations of the nature of Leigong's processed drugs: "Entering the liver, spleen, stomach, large intestine and kidney meridians."

It is mainly used for warming the middle warmer, relieving pain, regulating qi, eliminating dampness, treating vomiting, acid regurgitation, headache due to stranguria, abdominal distention and pain, abdominal pain during menstruation, diarrhea in the fifth watch, hypertension, beriberi, hernia, aphtha and ulcer, toothache, eczema, and impetigo.

① The Classic: "Regulating the middle warmer to lower the qi, relieving pain, coughing up cold and heat, removing dampness and blood stasis, expelling common cold, and dredging meridians."

② Bielu: "Treating phlegm cold, abdominal cramps, all coldness will not disappear, middle evil, heart and abdominal pain, reversing qi and benefiting five internal organs."

(3) The Theory of Medicinal Properties: "Main heart diseases, accumulation of cold, stagnation of qi under the heart, and heartburn; Cure cholera, turn tendons, cold air in the stomach, vomiting and diarrhea, abdominal pain and invincible ninja; "Cure the obstinacy all over the body, keep eating cold, and help the large intestine to support qi."

(4) The Addendum of Materia Medica: "Kill the evil insect poison, and the teeth will disappear."

⑤ "Rihuazi Materia Medica": "Spleen and joints. Treat abdominal pain, kidney qi, beriberi, edema and postpartum hemorrhage. "

⑥ Wang Haogu: "Treat fullness and obstruction of chest, obstruction of pharynx and diaphragm, moistening liver and drying spleen."

⑦ "Compendium": "Open stagnation and relieve stagnation. Treat acid swallowing, phlegm and saliva headache, abdominal pain, hernia, bloody dysentery and aphtha. "

Usage and dosage for oral administration: decoction, 0.5 ~ 2 yuan; Or into the pill, scattered. External use: steaming and ironing, grinding, dressing or frying and washing.

It is advisable to avoid people with yin deficiency and excessive fire.

① Notes on Materia Medica Classics: "I really do it. "Evil Danshen, Xiaoshi, chalk, fear of purple Shi Ying."

(2) "Herbal Medicine": "People with intestinal deficiency and diarrhea are especially taboo."

(3) Compendium: "Breathing, burning with fire, fainting eyes and getting sore."

(4) "Herbal Classics": "Vomiting and swallowing acid is not suitable for people with stomach fire; Cough against qi, which is not caused by exogenous pathogenic wind-cold and cold phlegm retention in water, should not be used; Abdominal pain is not suitable for those with blood deficiency and fire; Red and white diarrhea, due to summer evil into the stomach, rather than wine and food cold, stagnation and scale accumulation should not be used; Small intestinal hernia is not suitable for those who do not suddenly feel cold evil and have the first or second onset; Cholera turns tendons, which is caused by spleen and stomach weakness and summer heat, rather than cold and dampness, which is not suitable for those who commit gastrointestinal diseases; "All syndromes of yin deficiency and those with heat in the internal organs but no cold are taboo in the law."

Prescription 1: Treat the kidney qi rising on the throat, and the kidney qi builds up from the abdomen, but it can't vomit, or it can't breathe until it is dozens of times: Evodia rutaecarpa (fried with vinegar), orange peel and aconite root (peeled) one or two each. For the end, batter pills are big. Take seventy pills per ginger soup. ("Rencuntang Classic Prescriptions")

(2) Treating vinegar, every vinegar gas is like vinegar: cornus is combined. Three cups of water, fried for seven minutes, and taken immediately. Even if it is strong, it must be strong. ("Ministry of War Hand Sacrifice")

③ For those who have swallowed acid and stomach deficiency and cold, Evodia rutaecarpa (soaked in soup for seven times, baked) and dried ginger (processed) are equally divided. For the end, soup costs one yuan. ("Shenghuifang")

④ Treatment of liver fire: Coptidis Rhizoma, Fructus Evodiae, one or two or half two. The top is the end, water pills or steamed cake pills. Take fifty pills in white soup. (Zuo Jinwan, a Hui Ling Wan in Danxi Heart Method)

⑤ Patients with vomiting, chest fullness, dry vomiting and salivation, and headache: one liter of Evodia rutaecarpa, three ounces of ginseng, six ounces of ginger and twelve jujubes. Serve four flavors, five liters of water, three liters of boiling water, seven times of warm clothing, and three times a day. ("synopsis of the golden chamber" Wuzhuyu decoction)

⑥ Curing head wind: Evodia rutaecarpa three liters. Five liters of water, three liters of boiled water, and cotton hair. Root. ("Dry Golden Wing")

⑦ Cure phlegm, headache, cold back, vomiting sour juice, lying on the pillow for several days and not eating, once every ten days: Evodia rutaecarpa (soaked in soup for seven times) and Poria cocos. At the end, honey pills make a great child. Fifty pills per hot water, (Zhu's Collection of Folk Prescriptions)

⑧ Treating spleen diarrhea for many years, there are many elderly people, which is called water and soil assimilation: Evodia rutaecarpa San Qian. Soak, decoct the juice, add a little salt, and take it orally. Covering cornus can warm the bladder, and the waterway is clear, and the large intestine is self-solidified. Although other drugs are hot, they cannot be decomposed into turbidity. ("Rencuntang Classic Prescriptions")

⑨ Treat spleen with moisture, which leads to excessive diarrhea, delayed rice grains and stabbing pain in navel and abdomen; Children with malnutrition and diarrhea can also be treated: Coptis chinensis (removing beard), Evodia rutaecarpa (removing stem and frying) and Paeonia lactiflora. The top is fine powder, and the batter is pills, such as buttonwood. Take 20 pills each time, drink it with thick fried rice, and take it three times a day. ("Bureau Prescription" Wuji Pill)

Attending to treat beriberi, drowsiness and abdominal distension: six liters of Evodia rutaecarpa and two papaya (cut). To serve two flavors, take three liters of water in a bucket, boil three liters, and take three servings. If you walk for ten miles, take one serving, or vomit, or sweat, or benefit, or feel hot and stuffy, that is. ("Qian Jin Fang" Su Changshi cornus Tang)

⑾ To treat beriberi pain, if people feel rheumatism, foot pain is unbearable, and tendons and veins are swollen, they should be taken: seven areca nuts, one or two dried tangerine peel, one or two papaya, one San Qian for Evodia rutaecarpa, one for Perilla leaf, one half for Platycodon grandiflorum (reed removed) and one half for ginger (and peel). Fine-cut, water-fried, the next day at five o'clock, divided into three or five clothes, just cold clothes. A little warm clothing is also available in winter. ("The Criterion of Syndrome Treatment" Jiming Powder)

⑿ Treatment of hernia of small intestine in recent years, pain due to falling, pain due to pinching under the umbilicus, resulting in frowsty disorder, swelling and hardness of the external kidney, growing day by day, and wet itching in the underworld leading to sores: 1 kg of Evodia rutaecarpa (with branches removed) (soaked in wine for four purposes, soaked in vinegar for four purposes, soaked in soup for four purposes, soaked in urine for four purposes, soaked for one night each, and dried together), Alisma orientale (with the same baking). The top is fine powder, and the batter balls cooked with wine are as big as buttonwood. Take 50 pills each time, and swallow them with salt soup or wine before eating. ("The Bureau" kills Dan)

(13) Treatment of renal contraction in children (caused by neonatal cold): Evodia rutaecarpa, sulfur 50/50. Grind and coat the belly with garlic, and still smoke it with Fructus Cnidii. ("Shenghuifang")

[14] Treatment of aphtha and malnutrition: At the end of cornus, vinegar is applied to the heart. It also treats sore throat. ("Simple Prescription of Lakeside Collection")

⒂ Treatment of toothache: cornus decocted wine and gargled it. ("Dietotherapy Materia Medica")

⒃ Treating eczema: fry Evodia rutaecarpa for one or two, cuttlefish bone for seven dollars, and sulfur for two dollars. * * * Grind into fine powder for later use. Dry powder is sprinkled on patients with exudation from eczema; If there is no exudate, use castor oil or pig's plate oil to melt and spread it, once every other day, and wrap it with gauze after application. (Selected Works of the Whole Exhibition Dermatology)

⒄ Treatment of wet itching and sores under the yin: 1 liter of Evodia rutaecarpa, 3 liters of water, boiling for three or five times, removing me to wash the sores. Treat all kinds of sores. (Ancient and Modern Records of Folk Prescriptions)

⒅ Stroke (oblique mouth, unable to speak). Use one liter of cornus, three liters of ginger and five programs of sake, and fry for several times. After cooling, take half a liter each time. Take it three times a day. Slight sweat will heal.

Pet-name ruby itchy all over. Use one liter of cornus, add five liters of wine, boil it to one and a half liters, scrub it with warm water, and the itching will stop.

⒇ The winter and the moon are cold. Use Evodia rutaecarpa five money to decoct soup, and sweat as the degree.

(2 1) Vomiting, chest fullness and headache. Take one liter of cornus, twenty dates, one or two ginger and one or two ginseng, and add five liters of water to make three liters. Take seven times each time, twice a day. This recipe is called "Wuzhuyu Decoction".

(22) cold pain in the heart. Boil Evodia rutaecarpa with three liters of wine and take it three times.

(23) Small intestinal hernia (falling pain, swollen and hard testicles, wet and itchy). Use a catty of Evodia rutaecarpa (stem removed) and divide it into four parts. Soak in wine, vinegar, boiling water and toilet. After a night, take them out and bake them, add two taels of Alisma orientalis, grind them into powder, and mix them with wine and powder to make balls as big as wuzi. Take 50 pills each time, hollow clothes, salt soup or wine. This prescription is called "Desperate Dan", also known as "Star Fight Pill".

(24) Women are cold in the shade and will not get pregnant for a long time. Use 1 liter of Evodia rutaecarpa and 1 liter of Sichuan pepper, grind them into powder, and add honey to make balls as big as marbles. The wrapped cotton meat is included in the * * *, so that the uterus can be conceived.

(25) Stomach qi deficiency and cold, acid water in the mouth. Soak Evodia rutaecarpa in boiling water for seven times, take it out and bake it, add dried ginger (cannon) and divide it into powder. Every time you take a fee, hot soup is served.

(26) Turn the tendons into the abdomen. Use cornus (stir-fry) two ounces, add two bowls of wine, fry into a bowl, and take it twice. Diarrhea is the cure.

(27) the old man has been leaking water for many years. Soak Evodia rutaecarpa in San Qian, take it out, add water, and take it after adding a little salt.

(28) Red-white dysentery (dampness of spleen and stomach, diarrhea and abdominal pain, indigestion of rice). Stir-fry one or two of Evodia rutaecarpa, Coptis chinensis and Paeonia lactiflora, and add steamed cakes to make balls, which are as big as wuzi. Take 20 or 30 pills each time, and send rice soup. This prescription is called "Wuji Pill". Another recipe: stir-fry Chuanhuanglian No.2 Canyon and Evodia rutaecarpa (Tang Qin for seven times) together, grind them into powder respectively, and make them into balls with corn rice, if they are as big as wuzi, and store them for later use. Take thirty pills each time. For dysentery, take Huanglian Pill with licorice soup; White dysentery, take cornus pills with dried ginger soup; For red and white dysentery, take 15 pills each, and send rice soup. This prescription is called "Flexible Pill". Another recipe: use two ounces of Evodia rutaecarpa and two ounces of coptis chinensis, stir-fry them together, and each is the end. Use two or two pieces of paraquat, add rice and Rhizoma Coptidis to make balls; Two taels of white peony powder, rice and cornus were added to make balls, each as big as a wuzi, and stored for later use. Take fifty pills each time. Red dysentery, take Lianshuang pills with ebony soup; White dysentery, take Zhushao Pill with rice soup; Red and white dysentery, take 25 pills each. This prescription is called "Erse Pill".

(29) Abdominal mass. Mash it with a liter of cornus, cook it with wine, take out the pressed piece in the soft cloth, stir-fry it when it is cold, and then iron it. If the block moves, the ironing will also move until the accumulated block is eliminated.

(30) Tooth pain. Wash with cornus fried wine.

(3 1) rubella. Rub it with cornus Fried Wine.

(32) carbuncle and back. Pouring one liter of Evodia rutaecarpa into powder, adding bitter wine, coating and sticking it on the affected area.

(33) Strange diseases of cold and heat (chills and fever persist, and after a few days, the limbs are as hard as stones, and when they are knocked up, they sound like bronze, and they are getting thinner and thinner). Divide cornus and Radix Aucklandiae into equal parts, and decoct them to stimulate the oral administration.

The effect of Evodia rutaecarpa is to warm middle warmer, dispel cold, lower qi and relieve depression. In recent years, it has been practiced in clinic, and this product is also used to treat pinworm disease. Clinical practice believes that Evodia rutaecarpa has obvious analgesic and antiemetic effects.

Clinical application ① Treatment of hypertension

Grind Evodia rutaecarpa, take 0.6 ~12 each time, and apply vinegar to the soles of feet (preferably before going to bed, wrapped with cloth). Generally, after applying12 ~ 24 hours, the blood pressure began to drop, and the symptoms were relieved. Apply 1 time for mild symptoms, and 2 ~ 3 times for severe symptoms will show antihypertensive effect.

② Treatment of dyspepsia.

Take 2.5 ~ 3g of Evodia rutaecarpa powder, mix it with 5 ~ 6ml of vinegar, heat it to about 40℃, spread it on two layers of square gauze (about 0.5cm thick), and take 4 twists. Stick it on the navel and fix it with adhesive tape. 12 hour replacement 1 time. After treatment, 20 cases were cured 18 cases, improved 1 case and ineffective 1 case. Preliminary observation shows that this method has the functions of regulating gastrointestinal function, warming the interior to remove cold, relieving pain and helping digestion. It has a good effect on diarrhea caused by gastric dysfunction, and it can have a synergistic effect on diarrhea caused by bacterial infection with antibiotics.

③ Treating eczema and neurodermatitis.

Grinding Evodia rutaecarpa into powder, and mixing with vaseline into 30% (A) and 20% (B) ointments; Then take 30% Evodia rutaecarpa ointment and the same amount of zinc oxide ointment and mix them evenly to prepare compound Evodia rutaecarpa ointment (type C). For subacute and general chronic eczema, and scrotal eczema in subacute or early stage, use ointment B; For chronic scrotal eczema for many years, a ointment was used; Infantile eczema is treated with ointment C. Topically apply the medicine twice a day. For neurodermatitis, first apply ointment A, then cooperate with hot hair dryer, once a day 1 time, 20 minutes each time, and then stick it firmly with a piece of adhesive tape slightly larger than the skin lesion. According to the observation of 82 cases of eczema and neurodermatitis, the curative effect is good for early eczema and subacute eczema, and the cure time is short for 3 days; For general chronic eczema, the shortest cure time is 10 day; It is ineffective for chronic eczema with lichenoid transformation for many years; Infantile eczema 1 1 case, except for two cases that were ineffective, all were clinically cured within 7 ~15 days; The initial effect of scrotal eczema is obvious, but it is ineffective for those who have been ill for many years and are close to lichenoid transformation. Neurodermatitis 19 cases, all of which are mild and localized patients, are more effective than those who are simply coated with drugs. Four cases of localized neurodermatitis10 were treated with 10% Evodia rutaecarpa paste and then fumigated with moxa for 20 minutes. Results 4 cases were cured, 7 cases were significantly improved and 3 cases were improved. Cured cases are generally treated for 4 ~ 6 times. This method has remarkable antipruritic effect.

④ Treating yellow sores.

Grind Evodia rutaecarpa with vaseline to prepare 10% ointment, and apply it locally,1~ 2 times a day. Wash the affected area with warm water before rubbing the medicine: treatment 12 cases, usually recovered after 4 ~ 6 times.

⑤ Treat oral ulcer.

Mashing Evodia rutaecarpa, sieving, mixing fine powder with proper amount of good vinegar to make paste, applying it on gauze, applying it on bilateral Yongquan points, and taking it off after 24 hours. Dosage: 0.5 ~ 2 RMB for 1 under, 2 ~ 3 RMB for1~ 5 years old, 3 ~ 4 RMB for 6 ~ 15 years old, and 4 ~ 5 RMB for1over. 256 cases were treated and 247 cases were cured. General application 1 time is effective.

Remind you: Evodia rutaecarpa, a Chinese herbal medicine, comes from the Internet. Please follow the doctor's advice before using it.